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Depression is one of the most prevalent and debilitating mental health conditions worldwide, frequently underdiagnosed and undertreated. The proliferation of social media platforms provides a rich source of naturalistic linguistic signals…

Computation and Language · Computer Science 2026-04-23 Giorgia Gulino , Manuel Petrucci

Depression is one of the leading causes of disability worldwide, posing a severe burden on individuals, healthcare systems, and society at large. Recent advancements in Large Language Models (LLMs) have shown promise in addressing mental…

Computation and Language · Computer Science 2025-02-11 Shiyu Teng , Jiaqing Liu , Rahul Kumar Jain , Shurong Chai , Ruibo Hou , Tomoko Tateyama , Lanfen Lin , Yen-wei Chen

Large language models (LLMs) have demonstrated capabilities across diverse domains, yet their performance on rare disease diagnosis from narrative medical cases remains underexplored. We introduce a novel dataset of 176 symptom-diagnosis…

Computation and Language · Computer Science 2025-11-17 Arsh Gupta , Ajay Narayanan Sridhar , Bonam Mingole , Amulya Yadav

Large language models (LLMs) are becoming increasingly relevant as a potential tool for healthcare, aiding communication between clinicians, researchers, and patients. However, traditional evaluations of LLMs on medical exam questions do…

Computation and Language · Computer Science 2023-09-19 Rojin Ziaei , Samuel Schmidgall

With the significant expansion of the context window in Large Language Models (LLMs), these models are theoretically capable of processing millions of tokens in a single pass. However, research indicates a significant gap between this…

Computation and Language · Computer Science 2026-02-25 Nima Esmi , Maryam Nezhad-Moghaddam , Fatemeh Borhani , Asadollah Shahbahrami , Amin Daemdoost , Georgi Gaydadjiev

Large language models (LLMs) show promise for supporting clinicians in diagnostic communication by generating explanations and guidance for patients. Yet their ability to produce outputs that are both understandable and empathetic remains…

Computation and Language · Computer Science 2025-11-04 Jianzhou Yao , Shunchang Liu , Guillaume Drui , Rikard Pettersson , Alessandro Blasimme , Sara Kijewski

This study investigates whether large language models (LLMs) exhibit cross-linguistic differences in mental health evaluations. Focusing on Chinese and English, we examine two widely used models, GPT-4o and Qwen3, to assess whether prompt…

Computation and Language · Computer Science 2026-03-10 Jiayi Xu , Xiyang Hu

The emergence of Small Language Models (SLMs) as privacy-preserving alternatives for sensitive applications raises a fundamental question about their inherent understanding capabilities compared to Large Language Models (LLMs). This paper…

Computation and Language · Computer Science 2025-07-15 Hong Jia , Shiya Fu , Feng Xia , Vassilis Kostakos , Ting Dang

The increasing prevalence of mental disorders globally highlights the urgent need for effective digital screening methods that can be used in multilingual contexts. Most existing studies, however, focus on English data, overlooking critical…

Computation and Language · Computer Science 2026-01-27 Ana-Maria Bucur , Marcos Zampieri , Tharindu Ranasinghe , Fabio Crestani

Prior clinical psychology research shows that Western individuals with depression tend to report psychological symptoms, while Eastern individuals report somatic ones. We test whether Large Language Models (LLMs), which are increasingly…

Computation and Language · Computer Science 2025-08-06 Shintaro Sakai , Jisun An , Migyeong Kang , Haewoon Kwak

Large language models (LLMs) chatbots like ChatGPT are increasingly used for mental health support. They offer accessible, therapeutic support but also raise concerns about misinformation, over-reliance, and risks in high-stakes contexts of…

Computers and Society · Computer Science 2025-12-09 Lingyao Li , Xiaoshan Huang , Renkai Ma , Ben Zefeng Zhang , Haolun Wu , Fan Yang , Chen Chen

Mental health is increasingly critical in contemporary healthcare, with psychotherapy demanding dynamic, context-sensitive interactions that traditional NLP methods struggle to capture. Large Language Models (LLMs) offer significant…

Computation and Language · Computer Science 2025-06-30 Hongbin Na , Yining Hua , Zimu Wang , Tao Shen , Beibei Yu , Lilin Wang , Wei Wang , John Torous , Ling Chen

Depression remains widely underdiagnosed and undertreated because stigma and subjective symptom ratings hinder reliable screening. To address this challenge, we propose a coarse-to-fine, multi-stage framework that leverages large language…

Artificial Intelligence · Computer Science 2026-04-14 Shiyu Teng , Jiaqing Liu , Hao Sun , Yu Li , Shurong Chai , Ruibo Hou , Tomoko Tateyama , Lanfen Lin , Yen-Wei Chen

Advances in large language models (LLMs) have enabled a wide range of applications. However, depression prediction is hindered by the lack of large-scale, high-quality, and rigorously annotated datasets. This study introduces DepressLLM,…

Computation and Language · Computer Science 2025-08-13 Sehwan Moon , Aram Lee , Jeong Eun Kim , Hee-Ju Kang , Il-Seon Shin , Sung-Wan Kim , Jae-Min Kim , Min Jhon , Ju-Wan Kim

Large Language Models (LLMs) have fundamentally transformed approaches to Natural Language Processing (NLP) tasks across diverse domains. In healthcare, accurate and cost-efficient text classification is crucial, whether for clinical notes…

Computation and Language · Computer Science 2026-02-16 Hajar Sakai , Sarah S. Lam

Psychological support hotlines provide critical support for individuals experiencing mental health emergencies, yet current assessments largely rely on human operators whose judgments may vary with professional experience and are…

Computation and Language · Computer Science 2026-05-12 Terumi Chiba , Yang Luo , Ziyun Cui , Yongsheng Tong , Chao Zhang

The advent of large language models (LLMs) has significantly advanced various fields, including natural language processing and automated dialogue systems. This paper explores the application of LLMs in psychological counseling, addressing…

Computation and Language · Computer Science 2024-06-21 Wenjie Li , Tianyu Sun , Kun Qian , Wenhong Wang

The proliferation of Large Language Models (LLMs) in high-stakes applications such as medical (self-)diagnosis and preliminary triage raises significant ethical and practical concerns about the effectiveness, appropriateness, and possible…

Computers and Society · Computer Science 2025-06-18 Bonam Mingole , Aditya Majumdar , Firdaus Ahmed Choudhury , Jennifer L. Kraschnewski , Shyam S. Sundar , Amulya Yadav

Large language models (LLMs) have offered new opportunities for emotional support, and recent work has shown that they can produce empathic responses to people in distress. However, long-term mental well-being requires emotional…

Computation and Language · Computer Science 2024-08-09 Hongli Zhan , Allen Zheng , Yoon Kyung Lee , Jina Suh , Junyi Jessy Li , Desmond C. Ong

Large language models (LLMs) are increasingly being used in a zero-shot fashion to assess mental health conditions, yet we have limited knowledge on what factors affect their accuracy. In this study, we utilize a clinical dataset of natural…

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