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This paper compares the effectiveness of traditional machine learning methods, encoder-based models, and large language models (LLMs) on the task of detecting depression and anxiety. Five Russian-language datasets were considered, each…

Computation and Language · Computer Science 2025-11-04 Gleb Kuzmin , Petr Strepetov , Maksim Stankevich , Natalia Chudova , Artem Shelmanov , Ivan Smirnov

The rapid evolution of Large Language Models (LLMs) is transforming AI, opening new opportunities in sensitive and high-impact areas such as Mental Health (MH). Yet, despite these advancements, recent evidence reveals that smaller-scale…

Computation and Language · Computer Science 2025-10-21 Federico Ravenda , Seyed Ali Bahrainian , Andrea Raballo , Antonietta Mira

Large language models (LLMs) are already being piloted for clinical use in hospital systems like NYU Langone, Dana-Farber and the NHS. A proposed deployment use case is psychotherapy, where a LLM-powered chatbot can treat a patient…

Computation and Language · Computer Science 2024-10-10 Saadia Gabriel , Isha Puri , Xuhai Xu , Matteo Malgaroli , Marzyeh Ghassemi

Large Language Models (LLMs) have shown promise in various domains, including healthcare, with significant potential to transform mental health applications by enabling scalable and accessible solutions. This study aims to provide a…

Artificial Intelligence · Computer Science 2025-11-25 Abdelrahman Hanafi , Mohammed Saad , Noureldin Zahran , Radwa J. Hanafy , Mohammed E. Fouda

Large language models (LLMs) are emerging as promising tools for mental health care, offering scalable support through their ability to generate human-like responses. However, the effectiveness of these models in clinical settings remains…

Artificial Intelligence · Computer Science 2024-08-22 Yining Hua , Hongbin Na , Zehan Li , Fenglin Liu , Xiao Fang , David Clifton , John Torous

In response to the increasing mental health challenges faced by college students, we sought to understand their perspectives on how AI applications, particularly Large Language Models (LLMs), can be leveraged to enhance their mental…

Human-Computer Interaction · Computer Science 2024-09-27 Owen Xingjian Zhang , Shuyao Zhou , Jiayi Geng , Yuhan Liu , Sunny Xun Liu

Mental health disorders are increasingly prevalent worldwide, creating an urgent need for innovative tools to support early diagnosis and intervention. This study explores the potential of Large Language Models (LLMs) in multimodal mental…

Computation and Language · Computer Science 2025-08-14 Abdelrahman A. Ali , Aya E. Fouda , Radwa J. Hanafy , Mohammed E. Fouda

Difficult-to-treat depression (DTD) has been proposed as a broader and more clinically comprehensive perspective on a person's depressive disorder where despite treatment, they continue to experience significant burden. We sought to develop…

Computation and Language · Computer Science 2024-02-13 Isabelle Lorge , Dan W. Joyce , Niall Taylor , Alejo Nevado-Holgado , Andrea Cipriani , Andrey Kormilitzin

Large language models (LLMs) have made significant progress in various domains, including healthcare. However, the specialized nature of clinical language understanding tasks presents unique challenges and limitations that warrant further…

Computation and Language · Computer Science 2023-08-01 Yuqing Wang , Yun Zhao , Linda Petzold

The growing demand for accessible mental health support, compounded by workforce shortages and logistical barriers, has led to increased interest in utilizing Large Language Models (LLMs) for scalable and real-time assistance. However,…

Human-Computer Interaction · Computer Science 2025-05-27 Ugur Kursuncu , Trilok Padhi , Gaurav Sinha , Abdulkadir Erol , Jaya Krishna Mandivarapu , Christopher R. Larrison

Mental health conditions affect hundreds of millions globally, yet early detection remains limited. While large language models (LLMs) have shown promise in mental health applications, their size and computational demands hinder practical…

Artificial Intelligence · Computer Science 2025-12-17 Tianyi Zhang , Xiangyuan Xue , Lingyan Ruan , Shiya Fu , Feng Xia , Simon D'Alfonso , Vassilis Kostakos , Ting Dang , Hong Jia

The past decade has been transformative for mental health research and practice. The ability to harness large repositories of data, whether from electronic health records (EHR), mobile devices, or social media, has revealed a potential for…

Computation and Language · Computer Science 2023-11-28 Munmun De Choudhury , Sachin R. Pendse , Neha Kumar

Large language models (LLM) have been successful in several natural language understanding tasks and could be relevant for natural language processing (NLP)-based mental health application research. In this work, we report the performance…

Computation and Language · Computer Science 2023-03-29 Bishal Lamichhane

We propose a clinical decision support system (CDSS) for mental health diagnosis that combines the strengths of large language models (LLMs) and constraint logic programming (CLP). Having a CDSS is important because of the high complexity…

Artificial Intelligence · Computer Science 2025-02-24 Brian Hyeongseok Kim , Chao Wang

Recent research leverages large language models (LLMs) for early mental health detection, such as depression, often optimized with machine-generated data. However, their detection may be subject to unknown weaknesses. Meanwhile, quality…

Computation and Language · Computer Science 2025-05-26 Zongru Shao , Xin Wang , Zhanyang Liu , Chenhan Wang , K. P. Subbalakshmi

Advances in large language models (LLMs) have empowered a variety of applications. However, there is still a significant gap in research when it comes to understanding and enhancing the capabilities of LLMs in the field of mental health. In…

Computation and Language · Computer Science 2024-01-30 Xuhai Xu , Bingsheng Yao , Yuanzhe Dong , Saadia Gabriel , Hong Yu , James Hendler , Marzyeh Ghassemi , Anind K. Dey , Dakuo Wang

The global mental health crisis is looming with a rapid increase in mental disorders, limited resources, and the social stigma of seeking treatment. As the field of artificial intelligence (AI) has witnessed significant advancements in…

Computation and Language · Computer Science 2023-11-27 Neo Christopher Chung , George Dyer , Lennart Brocki

Mental health support in colleges is vital in educating students by offering counseling services and organizing supportive events. However, evaluating its effectiveness faces challenges like data collection difficulties and lack of…

Computation and Language · Computer Science 2024-12-06 Palak Sood , Chengyang He , Divyanshu Gupta , Yue Ning , Ping Wang

Large language models (LLMs) are increasingly proposed for crisis preparedness and response, particularly for multilingual communication. However, their suitability for high-stakes crisis contexts remains insufficiently evaluated. This work…

Computation and Language · Computer Science 2026-02-17 Belu Ticona , Antonis Anastasopoulos

The current work investigates the capability of Large language models (LLMs) that are explicitly trained on large corpuses of medical knowledge (Med-PaLM 2) to predict psychiatric functioning from patient interviews and clinical…

Computation and Language · Computer Science 2023-08-04 Isaac R. Galatzer-Levy , Daniel McDuff , Vivek Natarajan , Alan Karthikesalingam , Matteo Malgaroli