Related papers: Cyclic jetting enables microbubble-mediated drug d…
Systemic drug administration often causes off-target effects limiting the efficacy of advanced therapies. Targeted drug delivery approaches increase local drug concentrations at the diseased site while minimizing systemic drug exposure. We…
This paper investigates the relationship between the contact angle of a spherical bubble attached to a tube submerged in a container and the jet speed induced by an impulsive acceleration at its base. While it has been well established that…
Illuminating a water solution with a focused continuous wave laser produces a strong local heating of the liquid that leads to the nucleation of bubbles, also known as thermocavitation. During the growth of the bubble, the surrounding…
Ultrasound is known to enhance surface bubble growth and removal in catalytic and microfluidic applications, yet the contributions of rectified diffusion and microstreaming phenomena towards mass transfer remain unclear. We quantify the…
Drug delivery to the brain is limited by the blood-brain barrier (BBB). We developed a capacitive micromachined ultrasonic transducer (CMUT)-based transcranial focused ultrasound system capable of both delivering therapy via BBB opening and…
Focused ultrasound stimulated microbubbles have been shown to be capable of inducing blood flow shutdown and necrosis in a range of tissue types in an approach termed antivascular ultrasound or mechanical ablation. In oncology, this…
Jets and outflows from young stellar objects are proposed candidates to drive supersonic turbulence in molecular clouds. Here, we present the results from multi-dimensional jet simulations where we investigate in detail the energy and…
Understanding the shell rheology of ultrasound contrast agent microbubbles is vital for anticipating their bioeffects in clinical practice. Past studies using sophisticated acoustic and optical techniques have made enormous progress in this…
Ultrasound-matter interactions underpin numerous biomedical and soft-matter applications, yet simulating these phenomena is challenging due to the large separation of viscous and sonic time scales. Continuum methods capture large-scale wave…
In-body communication is an upcoming field with significant implications for medical diagnostics and therapeutic interventions. Microbubbles have gained attention due to their distinct physical properties, making them promising candidates…
Ultrasound offers promising applications in biology and chemistry, but quantifying local ultrasound conditions remains challenging due to the lack of non-invasive measurement tools. We introduce antibubbles as novel optical reporters of…
The influence of initial shape imperfections on the post-buckling and translational behavior of encapsulated microbubbles is investigated subject to acoustic excitation in an unbounded flow. Bifurcation analysis reveals that imperfections…
This study experimentally and numerically investigates the dynamics of a high-speed liquid jet generated from the interaction of two tandem cavitation bubbles, termed bubble 1 and bubble 2, depending on their generation sequence. In our…
Acoustic microstreaming has several industrial, therapeutic, and biomedical applications - Acoustic cleaning, micromixing, microfluid transport, hemolysis, sonoporation. The acoustic microstreaming due to the oscillation of ultrasound…
A popular method to induce synthetic propulsion at the microscale is to use the forces created by surface-produced gas bubbles inside the asymmetric body of a catalytic swimmer (referred to in the literature as microrocket). Gas bubbles…
An analytical theory is developed that describes acoustic microstreaming produced by the interaction of an oscillating gas bubble with a viscoelastic particle. The bubble is assumed to undergo axisymmetric oscillation modes, which can…
Jetting dynamics from bursting bubbles play a key role in mediating mass and momentum transport across the air-liquid interface. In marine environments, this phenomenon has drawn considerable attention due to its role in releasing…
On-demand controlled drug delivery is essential for the treatment of a wide range of chronic diseases. As the drug is released at the time when required, its efficacy is boosted and the side effects are minimized. However, so far, drug…
The benefits of ultrasound are its ease-of-use and its ability to precisely deliver energy in opaque and complex media. However, most materials responsive to ultrasound show a weak response, requiring the use of high powers, which are…
High speed microfluidic jets can be generated by a thermocavitation process: from the evaporation of the liquid inside a microfluidic channel, a rapidly expanding bubble is formed and generates a jet through a flow focusing effect. Here, we…