Related papers: Cyclic jetting enables microbubble-mediated drug d…
Mechanisms for non-invasive target drug delivery using microbubbles and ultrasound have attracted growing interest. Microbubbles can be loaded with a therapeutic payload and tracked via ultrasound imaging to selectively release their…
Acoustic droplet vaporization denotes the phase-change of micron- and sub-micron-sized droplets upon the application of high-amplitude ultrasound. The asymmetric collapse of the incepted vapor bubbles within the droplets can give rise to…
Microbubbles - used as contrast agents in ultrasound imaging - are important tools in biomedical research, having been used together with ultrasound to develop significant diagnostic and therapeutic techniques. It has been suggested that…
The dynamics of cavitation bubbles in the vicinity of a solid cylinder or fibre are seen in water treatment, demolition and/or cleaning of composite materials, as well as bio-medical scenarios such as ultrasound-induced bubbles near the…
Ultrasound contrast agents have been recently utilized in therapeutical implementations for targeted delivery of pharmaceutical substances. Radial pulsations of the encapsulated microbubbles under the action of an ultrasound field are…
We demonstrate that the permeability of the cell wall of microalga $\textit{C. reinhardtii}$ can be enhanced in controlled microstreaming flow conditions using single bubbles adherent to a wall and driven by ultrasound near their resonance…
Wall-attached bubbles can produce repeated jets under gentle ultrasound stimulation through the Faraday instability. We identify three distinct jetting regimes defined by the jetting frequency and the bubble surface topology. We demonstrate…
Powered by acoustics, existing therapeutic and diagnostic procedures will become less invasive and new methods will become available that have never been available before. Acoustically driven microrobot navigation based on microbubbles is a…
Contrast microbubbles (contrast agents) were initially developed to increase the contrast of the image in ultrasound imaging. These microbubbles consist of a gas core encapsulated by a layer of protein or lipid to stabilize them against…
Understanding how substrate-attached bubbles respond to ultrasound is important for applications from industrial cleaning to biomedical therapy. Under ultrasonic excitation, bubbles can deform through Faraday instability and periodically…
Microbubbles excited by acoustic fields inside water oscillate, and generate acoustic radiation forces and drag-induced acoustic streaming. These forces can be harnessed in various biomedical applications such as targeted drug delivery and…
Stiff and dense fibrin networks in chronic blood clots impede drug penetration and distribution into the clot core, limiting the efficacy of thrombolytic therapies. Acoustic cavitation of microbubbles is a promising strategy to enhance drug…
Controlled drug delivery (CDD), the controlled release and delivery of therapeutic drugs inside the human body, is a promising approach to increase the efficacy of drug administration and reduce harmful side effects to the body. CDD has…
Injecting with needles causes fear, pain and contamination risks. Billions of injections every year also cause environmental burden in terms of material consumption and waste. Controlled microfluidic-jet injection systems offer a…
Ultrasound contrast agents have been recently utilized in therapeutical implementations for targeted delivery of pharmaceutical substances. Radial pulsations of a cluster of encapsulated microbubbles under the action of an ultrasound field…
This paper considers the scenario of a targeted drug delivery system, which consists of deploying a number of biological nanomachines close to a biological target (e.g. a tumor), able to deliver drug molecules in the diseased area. Suitably…
Ultrasound-driven microbubbles are increasingly being investigated for both molecular imaging and therapeutic applications. To be effective, these bubbles must be brought into close proximity or direct contact with the target site.…
Mesoporous silica nanoparticles have been reported as suitable drug carriers, but their successful delivery to target tissues following systemic administration remains a challenge. In the present work, ultrasound-induced inertial cavitation…
Ultrasound-driven microbubbles rectify oscillatory motion into strong steady streaming flow [1, 2]. In this fluid dynamics video, we show size-dependent trapping, focusing and sorting of microparticles, utilizing the interaction between…
The development of needle-free drug injection systems is of great importance to global healthcare. However, in spite of its great potential and research history over many decades, these systems are not commonly used. One of the main…