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Since the emergence of the ImageNet dataset, the pretraining and fine-tuning approach has become widely adopted in computer vision due to the ability of ImageNet-pretrained models to learn a wide variety of visual features. However, a…

Computer Vision and Pattern Recognition · Computer Science 2024-10-22 Pablo Meseguer , Rocío del Amor , Adrian Colomer , Valery Naranjo

Pretraining on large-scale, in-domain datasets grants histopathology foundation models (FM) the ability to learn task-agnostic data representations, enhancing transfer learning on downstream tasks. In computational pathology, automated…

Computer Vision and Pattern Recognition · Computer Science 2025-07-22 Pablo Meseguer , Rocío del Amor , Valery Naranjo

The role of artificial intelligence (AI) in pathology has evolved from aiding diagnostics to uncovering predictive morphological patterns in whole slide images (WSIs). Recently, foundation models (FMs) leveraging self-supervised…

Foundation models (FMs) have emerged as a transformative paradigm in medical image analysis, offering the potential to provide generalizable, task-agnostic solutions across a wide range of clinical tasks and imaging modalities. Their…

Computer Vision and Pattern Recognition · Computer Science 2025-11-04 Karma Phuntsho , Abdullah , Kyungmi Lee , Ickjai Lee , Euijoon Ahn

Recent advances in artificial intelligence (AI), in particular self-supervised learning of foundation models (FMs), are revolutionizing medical imaging and computational pathology (CPath). A constant challenge in the analysis of digital…

The field of computational pathology has recently seen rapid advances driven by the development of modern vision foundation models (FMs), typically trained on vast collections of pathology images. Recent studies demonstrate that increasing…

Computer Vision and Pattern Recognition · Computer Science 2025-04-08 Mikhail Karasikov , Joost van Doorn , Nicolas Känzig , Melis Erdal Cesur , Hugo Mark Horlings , Robert Berke , Fei Tang , Sebastian Otálora

Neuro-oncology poses unique challenges for machine learning due to heterogeneous data and tumor complexity, limiting the ability of foundation models (FMs) to generalize across cohorts. Existing FMs also perform poorly in predicting…

Computer Vision and Pattern Recognition · Computer Science 2025-09-22 Moinak Bhattacharya , Angelica P. Kurtz , Fabio M. Iwamoto , Prateek Prasanna , Gagandeep Singh

Driven by the recent advances in deep learning methods and, in particular, by the development of modern self-supervised learning algorithms, increased interest and efforts have been devoted to build foundation models (FMs) for medical…

Computer Vision and Pattern Recognition · Computer Science 2024-04-24 kaiko. ai , Nanne Aben , Edwin D. de Jong , Ioannis Gatopoulos , Nicolas Känzig , Mikhail Karasikov , Axel Lagré , Roman Moser , Joost van Doorn , Fei Tang

Foundation models (FMs) promise to generalize medical imaging, but their effectiveness varies. It remains unclear how pre-training domain (medical vs. general), paradigm (e.g., text-guided), and architecture influence embedding quality,…

Data driven approaches have the potential to make modeling complex, nonlinear physical phenomena significantly more computationally tractable. For example, computational modeling of fracture is a core challenge where machine learning…

Machine Learning · Computer Science 2025-10-01 Erfan Hamdi , Emma Lejeune

Pathology has played a crucial role in the diagnosis and evaluation of patient tissue samples obtained from surgeries and biopsies for many years. The advent of Whole Slide Scanners and the development of deep learning technologies have…

Computer Vision and Pattern Recognition · Computer Science 2024-08-07 Mieko Ochi , Daisuke Komura , Shumpei Ishikawa

Despite the promise of computational pathology foundation models, adapting them to specific clinical tasks remains challenging due to the complexity of whole-slide image (WSI) processing, the opacity of learned features, and the wide range…

Computer Vision and Pattern Recognition · Computer Science 2025-11-26 Abdul Rahman Diab , Emily E. Karn , Renchin Wu , Emily S. Ruiz , William Lotter

Vision foundation models trained on discretely sampled images achieve strong performance on classification benchmarks, yet whether their representations encode the continuous processes underlying their training data remains unclear. This…

Computer Vision and Pattern Recognition · Computer Science 2026-01-30 Pritika Vig , Ren-Chin Wu , William Lotter

Foundation models for computational pathology are expected to facilitate the development of high-performing, generalisable deep learning systems. However, in addition to biologically relevant features, current foundation models also capture…

Due to the increase in computational resources and accessibility of data, an increase in large, deep learning models trained on copious amounts of multi-modal data using self-supervised or semi-supervised learning have emerged. These…

Computer Vision and Pattern Recognition · Computer Science 2024-04-30 Madeline Chantry Schiappa , Shehreen Azad , Sachidanand VS , Yunhao Ge , Ondrej Miksik , Yogesh S. Rawat , Vibhav Vineet

Histopathology foundation models (HFMs), pretrained on large-scale cancer datasets, have advanced computational pathology. However, their applicability to non-cancerous chronic kidney disease remains underexplored, despite coexistence of…

Neural networks achieve state-of-the-art performance in many supervised learning tasks when the training data distribution matches the test data distribution. However, their performance drops significantly under domain (covariate) shift, a…

Computer Vision and Pattern Recognition · Computer Science 2024-09-13 Kerem Cekmeceli , Meva Himmetoglu , Guney I. Tombak , Anna Susmelj , Ertunc Erdil , Ender Konukoglu

Constructing a robust model that can effectively generalize to test samples under distribution shifts remains a significant challenge in the field of medical imaging. The foundational models for vision and language, pre-trained on extensive…

Remarkable strides in computational pathology have been made in the task-agnostic foundation model that advances the performance of a wide array of downstream clinical tasks. Despite the promising performance, there are still several…

Pathology foundation models (PFMs) have advanced rapidly in recent years and support training classifiers for a range of histopathology tasks. However, their robustness across hospitals remains limited: performance often degrades when…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Ben Vardi , Dana Schonberger , Yuval Friedmann , Zohar Yakhini , Iris Barshack , Alexander Loebel , Ariel Shamir