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Current deep learning models are mostly task specific and lack a user-friendly interface to operate. We present Meta-EyeFM, a multi-function foundation model that integrates a large language model (LLM) with vision foundation models (VFMs)…

The rising prevalence of eye diseases poses a growing public health burden. Large language models (LLMs) offer a promising path to reduce documentation workload and support clinical decision-making. However, few have been tailored for…

Accurate and interpretable multi-disease diagnosis remains a critical challenge in medical research, particularly when leveraging heterogeneous multimodal medical data. Current approaches often rely on single-modal data, limiting their…

Image and Video Processing · Electrical Eng. & Systems 2025-06-25 Yuting Zhang , Kaishen Yuan , Hao Lu , Yutao Yue , Jintai Chen , Kaishun Wu

Multimodal large language models (MLLMs) have achieved impressive performance across various tasks such as image captioning and visual question answer(VQA); however, they often struggle to accurately interpret depth information inherent in…

Computer Vision and Pattern Recognition · Computer Science 2026-03-09 Hao Yang , Hongbo Zhang , Yanyan Zhao , Bing Qin

In the era of modern healthcare, swiftly generating medical question summaries is crucial for informed and timely patient care. Despite the increasing complexity and volume of medical data, existing studies have focused solely on text-based…

Artificial Intelligence · Computer Science 2023-12-20 Akash Ghosh , Arkadeep Acharya , Raghav Jain , Sriparna Saha , Aman Chadha , Setu Sinha

Recently, there has been a growing interest in Multimodal Large Language Models (MLLMs) due to their remarkable potential in various tasks integrating different modalities, such as image and text, as well as applications such as image…

Computer Vision and Pattern Recognition · Computer Science 2024-09-30 Jihen Amara , Birgitta König-Ries , Sheeba Samuel

Large vision-language models (LVLMs) demonstrate strong performance in dermatology; however, evaluating diagnostic reasoning for rare conditions remains largely unexplored. Existing benchmarks focus on common diseases and assess only final…

Computer Vision and Pattern Recognition · Computer Science 2026-03-20 Yang Liu , Jiyao Yang , Hongjin Zhao , Xiaoyong Li , Yanzhe Ji , Xingjian Li , Runmin Jiang , Tianyang Wang , Saeed Anwar , Dongwoo Kim , Yue Yao , Zhenyue Qin , Min Xu

Large language models (LLMs) have recently demonstrated their potential in clinical applications, providing valuable medical knowledge and advice. For example, a large dialog LLM like ChatGPT has successfully passed part of the US medical…

Computer Vision and Pattern Recognition · Computer Science 2023-02-15 Sheng Wang , Zihao Zhao , Xi Ouyang , Qian Wang , Dinggang Shen

We propose a clinical decision support system (CDSS) for mental health diagnosis that combines the strengths of large language models (LLMs) and constraint logic programming (CLP). Having a CDSS is important because of the high complexity…

Artificial Intelligence · Computer Science 2025-02-24 Brian Hyeongseok Kim , Chao Wang

Large multimodal language models (LMMs) have achieved significant success in general domains. However, due to the significant differences between medical images and text and general web content, the performance of LMMs in medical scenarios…

Computer Vision and Pattern Recognition · Computer Science 2023-06-23 Weihao Gao , Zhuo Deng , Zhiyuan Niu , Fuju Rong , Chucheng Chen , Zheng Gong , Wenze Zhang , Daimin Xiao , Fang Li , Zhenjie Cao , Zhaoyi Ma , Wenbin Wei , Lan Ma

Visual impairment represents a major global health challenge, with multimodal imaging providing complementary information that is essential for accurate ophthalmic diagnosis. This comprehensive survey systematically reviews the latest…

Image and Video Processing · Electrical Eng. & Systems 2025-08-07 Xiaoling Luo , Ruli Zheng , Qiaojian Zheng , Zibo Du , Shuo Yang , Meidan Ding , Qihao Xu , Chengliang Liu , Linlin Shen

The capability to process multiple images is crucial for Large Vision-Language Models (LVLMs) to develop a more thorough and nuanced understanding of a scene. Recent multi-image LVLMs have begun to address this need. However, their…

Computer Vision and Pattern Recognition · Computer Science 2024-08-07 Fanqing Meng , Jin Wang , Chuanhao Li , Quanfeng Lu , Hao Tian , Jiaqi Liao , Xizhou Zhu , Jifeng Dai , Yu Qiao , Ping Luo , Kaipeng Zhang , Wenqi Shao

Despite significant progress in Multi-modal Large Language Models (MLLMs), their clinical reasoning capacity for multi-modal diagnosis remains largely unexamined. Current benchmarks, mostly single-modality data, can't evaluate progressive…

Computer Vision and Pattern Recognition · Computer Science 2026-04-23 Gui Wang , Zehao Zhong , YongSong Zhou , Yudong Li , Ende Wu , Wooi Ping Cheah , Rong Qu , Jianfeng Ren , Linlin Shen

Medical vision language pre-training (VLP) has emerged as a frontier of research, enabling zero-shot pathological recognition by comparing the query image with the textual descriptions for each disease. Due to the complex semantics of…

Computer Vision and Pattern Recognition · Computer Science 2024-04-02 Vu Minh Hieu Phan , Yutong Xie , Yuankai Qi , Lingqiao Liu , Liyang Liu , Bowen Zhang , Zhibin Liao , Qi Wu , Minh-Son To , Johan W. Verjans

The advancement of Large Vision-Language Models (LVLMs) has propelled their application in the medical field. However, Medical LVLMs (Med-LVLMs) encounter factuality challenges due to modality misalignment, where the models prioritize…

Computer Vision and Pattern Recognition · Computer Science 2025-06-05 Kangyu Zhu , Peng Xia , Yun Li , Hongtu Zhu , Sheng Wang , Huaxiu Yao

Globally, there is a substantial unmet need to diagnose various diseases effectively. The complexity of the different disease mechanisms and underlying symptoms of the patient population presents massive challenges to developing the early…

Machine Learning · Computer Science 2022-01-03 Md Manjurul Ahsan , Zahed Siddique

The inability to interpret the model prediction in semantically and visually meaningful ways is a well-known shortcoming of most existing computer-aided diagnosis methods. In this paper, we propose MDNet to establish a direct multimodal…

Computer Vision and Pattern Recognition · Computer Science 2017-07-11 Zizhao Zhang , Yuanpu Xie , Fuyong Xing , Mason McGough , Lin Yang

In diagnostic reports, experts encode complex imaging data into clinically actionable information. They describe subtle pathological findings that are meaningful in their anatomical context. Reports follow relatively consistent structures,…

Computer Vision and Pattern Recognition · Computer Science 2026-04-16 Felicia Bader , Philipp Seeböck , Anastasia Bartashova , Ulrike Attenberger , Georg Langs

MLLMs have recently become a focal point in the field of artificial intelligence research. Building on the strong capabilities of LLMs, MLLMs are adept at addressing complex multi-modal tasks. With the release of GPT-4, MLLMs have gained…

Machine Learning · Computer Science 2025-05-01 Jiarui Ye , Hao Tang

This paper attacks an emerging challenge of multi-modal retinal disease recognition. Given a multi-modal case consisting of a color fundus photo (CFP) and an array of OCT B-scan images acquired during an eye examination, we aim to build a…

Computer Vision and Pattern Recognition · Computer Science 2021-09-28 Xirong Li , Yang Zhou , Jie Wang , Hailan Lin , Jianchun Zhao , Dayong Ding , Weihong Yu , Youxin Chen