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Large language models (LLMs) show promise for supporting clinicians in diagnostic communication by generating explanations and guidance for patients. Yet their ability to produce outputs that are both understandable and empathetic remains…

Computation and Language · Computer Science 2025-11-04 Jianzhou Yao , Shunchang Liu , Guillaume Drui , Rikard Pettersson , Alessandro Blasimme , Sara Kijewski

Doctors and patients alike increasingly use Large Language Models (LLMs) to diagnose clinical cases. However, unlike domains such as math or coding, where correctness can be objectively defined by the final answer, medical diagnosis…

Computation and Language · Computer Science 2025-05-21 Kevin Wu , Eric Wu , Rahul Thapa , Kevin Wei , Angela Zhang , Arvind Suresh , Jacqueline J. Tao , Min Woo Sun , Alejandro Lozano , James Zou

In healthcare intelligence, the ability to fuse heterogeneous, multi-intent information from diverse clinical sources is fundamental to building reliable decision-making systems. Large Language Model (LLM)-driven information interaction…

Computation and Language · Computer Science 2025-07-04 Dingkang Yang , Jinjie Wei , Mingcheng Li , Jiyao Liu , Lihao Liu , Ming Hu , Junjun He , Yakun Ju , Wei Zhou , Yang Liu , Lihua Zhang

Generalist vision language models (VLMs) have made significant strides in computer vision, but they fall short in specialized fields like healthcare, where expert knowledge is essential. In traditional computer vision tasks, creative or…

Machine Learning (ML) has garnered considerable attention from researchers and practitioners as a new and adaptable tool for disease diagnosis. With the advancement of ML and the proliferation of papers and research in this field, a…

Machine Learning · Computer Science 2022-01-11 Md Manjurul Ahsan , Zahed Siddique

Machine learning (ML) research has yielded powerful tools for training accurate prediction models despite complex multivariate associations (e.g. interactions and heterogeneity). In fields such as medicine, improved interpretability of ML…

Machine Learning · Computer Science 2021-04-28 Robert Zhang , Rachael Stolzenberg-Solomon , Shannon M. Lynch , Ryan J. Urbanowicz

The use of machine learning (ML) techniques in the biomedical field has become increasingly important, particularly with the large amounts of data generated by the aftermath of the COVID-19 pandemic. However, due to the complex nature of…

Machine Learning · Computer Science 2023-03-17 Anthony Onoja , Francesco Raimondi

Clinical reasoning refers to the cognitive process that physicians employ in evaluating and managing patients. This process typically involves suggesting necessary examinations, diagnosing patients' diseases, and deciding on appropriate…

Computation and Language · Computer Science 2024-06-11 Jiageng WU , Xian Wu , Jie Yang

Oral mucosal diseases such as leukoplakia, oral lichen planus, and recurrent aphthous ulcers exhibit diverse and overlapping visual features, making diagnosis challenging for non-specialists. While vision-language models (VLMs) have shown…

Quantitative Methods · Quantitative Biology 2025-10-17 Jia Zhang , Bodong Du , Yitong Miao , Dongwei Sun , Xiangyong Cao

With appropriate data selection and training techniques, Large Language Models (LLMs) have demonstrated exceptional success in various medical examinations and multiple-choice questions. However, the application of LLMs in medical dialogue…

Computation and Language · Computer Science 2024-03-12 Jiageng Wu , Xian Wu , Yefeng Zheng , Jie Yang

Multiparametric 3D brain MRI (mpMRI) is central to neuroradiology, but producing tumor location, appearance, size, and involvement of critical structures for neurosurgical planning remains challenging. We introduce mpLLM, a multimodal LLM…

Computer Vision and Pattern Recognition · Computer Science 2026-02-16 Arvind Murari Vepa , Yannan Yu , Jingru Gan , Anthony Cuturrufo , Michael F. Romano , Weikai Li , Fabien Scalzo , Wei Wang , Yizhou Sun

Open-source, multilingual medical large language models (LLMs) have the potential to serve linguistically diverse populations across different regions. Adapting generic LLMs for healthcare often requires continual pretraining, but this…

Computation and Language · Computer Science 2024-09-10 Meng Zhou , Surajsinh Parmar , Anubhav Bhatti

Despite the growing adoption of electronic health records, many processes still rely on paper documents, reflecting the heterogeneous real-world conditions in which healthcare is delivered. The manual transcription process is time-consuming…

Multimodal large language models (MLLMs) have demonstrated promise on publicly available dermatology benchmarks. However, benchmark performance may not generalize to real-world dermatologic decision-making. To quantify this…

Computer Vision and Pattern Recognition · Computer Science 2026-05-07 Roy Jiang , Hyunjae Kim , Zhenyue Qin , Morten Lee , Margaret MacGibeny , Ailish Hanly , Angela Sadlowski , Shanin Chowdhury , Xuguang Ai , Jeffrey Gehlhausen , Qingyu Chen

In the field of industrial inspection, Multimodal Large Language Models (MLLMs) have a high potential to renew the paradigms in practical applications due to their robust language capabilities and generalization abilities. However, despite…

Artificial Intelligence · Computer Science 2025-02-24 Xi Jiang , Jian Li , Hanqiu Deng , Yong Liu , Bin-Bin Gao , Yifeng Zhou , Jialin Li , Chengjie Wang , Feng Zheng

The convolutional-based methods provide good segmentation performance in the medical image segmentation task. However, those methods have the following challenges when dealing with the edges of the medical images: (1) Previous…

Image and Video Processing · Electrical Eng. & Systems 2022-08-24 Jinkai Lv , Yuyong Hu , Quanshui Fu , Zhiwang Zhang , Yuqiang Hu , Lin Lv , Guoqing Yang , Jinpeng Li , Yi Zhao

Visual spatial intelligence is critical for medical image interpretation, yet remains largely unexplored in Multimodal Large Language Models (MLLMs) for 3D imaging. This gap persists due to a systemic lack of datasets featuring structured…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Quoc-Huy Trinh , Xi Ding , Yang Liu , Zhenyue Qin , Xingjian Li , Gorkem Durak , Halil Ertugrul Aktas , Elif Keles , Ulas Bagci , Min Xu

Vision--language models (VLMs) show promise for clinical decision support in radiology because they enable joint reasoning over radiological images and clinical text, thereby leveraging complementary clinical information. However,…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Haozhe Luo , Shelley Zixin Shu , Ziyu Zhou , Robert Berke , Mauricio Reyes

Large annotated datasets are essential for training robust Computer-Aided Diagnosis (CAD) models for breast cancer detection or risk prediction. However, acquiring such datasets with fine-detailed annotation is both costly and…

Computer Vision and Pattern Recognition · Computer Science 2025-10-31 Shunjie-Fabian Zheng , Hyeonjun Lee , Thijs Kooi , Ali Diba

Large Language Models (LLMs) are revolutionizing medical diagnostics by enhancing both disease classification and clinical decision-making. In this study, we evaluate the performance of two LLM- based diagnostic tools, DeepSeek R1 and O3…

Computation and Language · Computer Science 2025-06-23 Gaurav Kumar Gupta , Pranal Pande , Nirajan Acharya , Aniket Kumar Singh , Suman Niroula
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