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Recently, Multimodal Large Language Models (MLLMs) have gained significant attention for their remarkable ability to process and analyze non-textual data, such as images, videos, and audio. Notably, several adaptations of general-domain…

Computer Vision and Pattern Recognition · Computer Science 2025-03-07 Wenhui Zhu , Xin Li , Xiwen Chen , Peijie Qiu , Vamsi Krishna Vasa , Xuanzhao Dong , Yanxi Chen , Natasha Lepore , Oana Dumitrascu , Yi Su , Yalin Wang

Vision-language foundation models (VLMs) have shown great potential in feature transfer and generalization across a wide spectrum of medical-related downstream tasks. However, fine-tuning these models is resource-intensive due to their…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Ye Du , Nanxi Yu , Shujun Wang

Vision-Language Models (VLMs), exemplified by CLIP, have emerged as foundational for multimodal intelligence. However, their capacity for logical understanding remains significantly underexplored, resulting in critical ''logical…

Computer Vision and Pattern Recognition · Computer Science 2025-08-18 Yuchen Zhou , Jiayu Tang , Shuo Yang , Xiaoyan Xiao , Yuqin Dai , Wenhao Yang , Chao Gou , Xiaobo Xia , Tat-Seng Chua

Multimodal ophthalmic imaging-based diagnosis integrates color fundus image with optical coherence tomography (OCT) to provide a comprehensive view of ocular pathologies. However, the uneven global distribution of healthcare resources often…

Computer Vision and Pattern Recognition · Computer Science 2025-07-08 Qinkai Yu , Jianyang Xie , Yitian Zhao , Cheng Chen , Lijun Zhang , Liming Chen , Jun Cheng , Lu Liu , Yalin Zheng , Yanda Meng

The emergence of large language models (LLMs) has significantly influenced numerous fields, including healthcare, by enhancing the capabilities of automated systems to process and generate human-like text. However, despite their…

Information Retrieval · Computer Science 2025-04-23 Mohit Gupta , Akiko Aizawa , Rajiv Ratn Shah

Despite strong performance in medical question-answering, the clinical adoption of Large Language Models (LLMs) is critically hampered by their opaque 'black-box' reasoning, limiting clinician trust. This challenge is compounded by the…

Computer Vision and Pattern Recognition · Computer Science 2025-05-13 Chao Ding , Mouxiao Bian , Pengcheng Chen , Hongliang Zhang , Tianbin Li , Lihao Liu , Jiayuan Chen , Zhuoran Li , Yabei Zhong , Yongqi Liu , Haiqing Huang , Dongming Shan , Junjun He , Jie Xu

Clinical measurement of a patient's axial eye length is emerging as a crucial approach to track progression and monitor management of myopia. However, the preferred method for such measurements is swept-source OCT, whose cost prohibits…

Medical document analysis plays a crucial role in extracting essential clinical insights from unstructured healthcare records, supporting critical tasks such as differential diagnosis. Determining the most probable condition among…

Artificial Intelligence · Computer Science 2025-06-25 Lei Kang , Xuanshuo Fu , Oriol Ramos Terrades , Javier Vazquez-Corral , Ernest Valveny , Dimosthenis Karatzas

Automated data preparation is crucial for democratizing machine learning, yet existing reinforcement learning (RL) based approaches suffer from inefficient exploration in the vast space of possible preprocessing pipelines. We present…

Databases · Computer Science 2025-07-21 Jing Chang , Chang Liu , Jinbin Huang , Rui Mao , Jianbin Qin

Detecting microbial biomarkers used to predict disease phenotypes and clinical outcomes is crucial for disease early-stage screening and diagnosis. Most methods for biomarker identification are linear-based, which is very limited as…

Quantitative Methods · Quantitative Biology 2021-09-29 Jian Jiang

Liver cirrhosis is a major global health problem causing millions of deaths annually, and timely detection with aggressive treatment can significantly improve patients' quality of life. Modelling complex diseases from biomedical data is…

Other Quantitative Biology · Quantitative Biology 2026-04-29 Xueyuan Huang , Yuheng Wang , Yuanzhi He , Siqi Gou , Lu Bai , Wenqian Wu , Peifeng Liu , Aijia Wang , Tianhui Fan , Ze Zhou , Jiayu Xu

Large Language Models (LLMs) are increasingly proposed for clinical decision support including multilingual diagnosis in low-resource settings. However, their reliability, calibration and safety characteristics remain insufficiently…

Computation and Language · Computer Science 2026-05-05 Danish Ali , Li Xiaojian , Sundas Iqbal , Farrukh Zaidi

The increasing global prevalence of mental disorders, such as depression and PTSD, requires objective and scalable diagnostic tools. Traditional clinical assessments often face limitations in accessibility, objectivity, and consistency.…

Audio and Speech Processing · Electrical Eng. & Systems 2025-04-03 Abdelrahaman A. Hassan , Abdelrahman A. Ali , Aya E. Fouda , Radwa J. Hanafy , Mohammed E. Fouda

The rapid development of multimodal large language models (MLLMs), such as GPT-4V, has led to significant advancements. However, these models still face challenges in medical multimodal capabilities due to limitations in the quantity and…

Computer Vision and Pattern Recognition · Computer Science 2024-10-01 Junying Chen , Chi Gui , Ruyi Ouyang , Anningzhe Gao , Shunian Chen , Guiming Hardy Chen , Xidong Wang , Ruifei Zhang , Zhenyang Cai , Ke Ji , Guangjun Yu , Xiang Wan , Benyou Wang

Recently computer-aided diagnosis has demonstrated promising performance, effectively alleviating the workload of clinicians. However, the inherent sample imbalance among different diseases leads algorithms biased to the majority…

Computer Vision and Pattern Recognition · Computer Science 2025-02-10 Li Pan , Yupei Zhang , Qiushi Yang , Tan Li , Zhen Chen

Optical emission spectroscopy of laser-produced plasmas, commonly known as laser-induced breakdown spectroscopy (LIBS), is an emerging analytical tool for rapid soil analysis. However, specific challenges with LIBS exist, such as matrix…

Signal Processing · Electrical Eng. & Systems 2022-08-17 Yingchao Huang , Sivanandan S. Harilal , Abdul Bais , Amina E. Hussein

With the rapid advancement of Multimodal Large Language Models (MLLMs), a variety of benchmarks have been introduced to evaluate their capabilities. While most evaluations have focused on complex tasks such as scientific comprehension and…

Computer Vision and Pattern Recognition · Computer Science 2024-12-24 Huan Liu , Lingyu Xiao , Jiangjiang Liu , Xiaofan Li , Ze Feng , Sen Yang , Jingdong Wang

Timely identification and accurate risk stratification of cardiovascular disease (CVD) remain essential for reducing global mortality. While existing prediction models primarily leverage structured data, unstructured clinical notes contain…

Computation and Language · Computer Science 2025-07-16 Haowei Yang , Ziyu Shen , Junli Shao , Luyao Men , Xinyue Han , Jing Dong

The variety of data in data lakes presents significant challenges for data analytics, as data scientists must simultaneously analyze multi-modal data, including structured, semi-structured, and unstructured data. While Large Language Models…

Databases · Computer Science 2025-05-19 Chao Zhang , Shaolei Zhang , Quehuan Liu , Sibei Chen , Tong Li , Ju Fan

We explore Multimodal Large Language Models (MLLMs), which integrate LLMs like GPT-4 to handle multimodal data, including text, images, audio, and more. MLLMs demonstrate capabilities such as generating image captions and answering…

Computation and Language · Computer Science 2025-01-09 Shezheng Song , Xiaopeng Li , Shasha Li , Shan Zhao , Jie Yu , Jun Ma , Xiaoguang Mao , Weimin Zhang