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Mapping X-ray images, radiology reports, and other medical data as binary codes in the common space, which can assist clinicians to retrieve pathology-related data from heterogeneous modalities (i.e., hashing-based cross-modal medical data…

Machine Learning · Computer Science 2022-05-18 Yufeng Shi , Shuhuang Chen , Xinge You , Qinmu Peng , Weihua Ou , Yue Zhao

Multimodal Fusion Learning (MFL), leveraging disparate data from various imaging modalities (e.g., MRI, CT, SPECT), has shown great potential for addressing medical problems such as skin cancer and brain tumor prediction. However, existing…

Computer Vision and Pattern Recognition · Computer Science 2026-02-18 Joy Dhar , Nayyar Zaidi , Maryam Haghighat

Medical multimodal representation learning aims to integrate heterogeneous data into unified patient representations to support clinical outcome prediction. However, real-world medical datasets commonly contain systematic biases from…

Machine Learning · Computer Science 2026-05-19 Xiaoguang Zhu , Linxiao Gong , Lianlong Sun , Yang Liu , Haoyu Wang , Jing Liu

Accurately predicting molecular properties is a challenging but essential task in drug discovery. Recently, many mono-modal deep learning methods have been successfully applied to molecular property prediction. However, the inherent…

Machine Learning · Computer Science 2024-09-16 Xiaohua Lu , Liangxu Xie , Lei Xu , Rongzhi Mao , Shan Chang , Xiaojun Xu

Large language models applied to vast biological datasets have the potential to transform biology by uncovering disease mechanisms and accelerating drug development. However, current models are often siloed, trained separately on…

With the increasing availability of diverse data types, particularly images and time series data from medical experiments, there is a growing demand for techniques designed to combine various modalities of data effectively. Our motivation…

Image and Video Processing · Electrical Eng. & Systems 2024-05-27 Ali Rasekh , Reza Heidari , Amir Hosein Haji Mohammad Rezaie , Parsa Sharifi Sedeh , Zahra Ahmadi , Prasenjit Mitra , Wolfgang Nejdl

Multimodal deep learning utilizing imaging and diagnostic reports has made impressive progress in the field of medical imaging diagnostics, demonstrating a particularly strong capability for auxiliary diagnosis in cases where sufficient…

Computer Vision and Pattern Recognition · Computer Science 2024-08-21 Hao Yang , Hong-Yu Zhou , Cheng Li , Weijian Huang , Jiarun Liu , Yong Liang , Guangming Shi , Hairong Zheng , Qiegen Liu , Shanshan Wang

Multimodal machine learning (MML) is rapidly reshaping the way mental-health disorders are detected, characterized, and longitudinally monitored. Whereas early studies relied on isolated data streams -- such as speech, text, or wearable…

Machine Learning · Computer Science 2025-06-25 Zahraa Al Sahili , Ioannis Patras , Matthew Purver

The healthcare domain is characterized by heterogeneous data modalities, such as imaging and physiological data. In practice, the variety of medical data assists clinicians in decision-making. However, most of the current state-of-the-art…

Image and Video Processing · Electrical Eng. & Systems 2021-11-05 Nasir Hayat , Krzysztof J. Geras , Farah E. Shamout

Multimodal data modeling has emerged as a powerful approach in clinical research, enabling the integration of diverse data types such as imaging, genomics, wearable sensors, and electronic health records. Despite its potential to improve…

A key challenge in learning from multimodal biological data is missing modalities, where data from one or more modalities are absent for some patients. Existing approaches either exclude patients with missing modalities, impute missing…

Machine Learning · Computer Science 2026-05-19 Sina Tabakhi , Chen , Chen , Haiping Lu

Understanding brain disorders is crucial for accurate clinical diagnosis and treatment. Recent advances in Multimodal Large Language Models (MLLMs) offer a promising approach to interpreting medical images with the support of text…

Image and Video Processing · Electrical Eng. & Systems 2025-06-03 Jing Zhang , Xiaowei Yu , Yanjun Lyu , Lu Zhang , Tong Chen , Chao Cao , Yan Zhuang , Minheng Chen , Tianming Liu , Dajiang Zhu

Medical data poses a daunting challenge for AI algorithms: it exists in many different modalities, experiences frequent distribution shifts, and suffers from a scarcity of examples and labels. Recent advances, including transformers and…

Ophthalmologists typically require multimodal data sources to improve diagnostic accuracy in clinical decisions. However, due to medical device shortages, low-quality data and data privacy concerns, missing data modalities are common in…

Computer Vision and Pattern Recognition · Computer Science 2025-02-18 Chengzhi Liu , Zile Huang , Zhe Chen , Feilong Tang , Yu Tian , Zhongxing Xu , Zihong Luo , Yalin Zheng , Yanda Meng

Liver cancer is one of the most common cancers worldwide. Due to inconspicuous texture changes of liver tumor, contrast-enhanced computed tomography (CT) imaging is effective for the diagnosis of liver cancer. In this paper, we focus on…

Image and Video Processing · Electrical Eng. & Systems 2021-07-22 Yao Zhang , Jiawei Yang , Jiang Tian , Zhongchao Shi , Cheng Zhong , Yang Zhang , Zhiqiang He

Recent studies have made significant progress in developing large language models (LLMs) in the medical domain, which can answer expert-level questions and demonstrate the potential to assist clinicians in real-world clinical scenarios.…

Computation and Language · Computer Science 2025-04-18 Sangwook Kim , Soonyoung Lee , Jongseong Jang

In clinical practice, multi-modal magnetic resonance imaging (MRI) with different contrasts is usually acquired in a single study to assess different properties of the same region of interest in the human body. The whole acquisition process…

Image and Video Processing · Electrical Eng. & Systems 2022-04-05 Kai Xuan , Lei Xiang , Xiaoqian Huang , Lichi Zhang , Shu Liao , Dinggang Shen , Qian Wang

Automatic integration of whole slide images (WSIs) and gene expression profiles has demonstrated substantial potential in precision clinical diagnosis and cancer progression studies. However, most existing studies focus on individual gene…

Computer Vision and Pattern Recognition · Computer Science 2026-01-14 Junzhuo Liu , Xuemei Du , Daniel Reisenbuchler , Ye Chen , Markus Eckstein , Christian Matek , Friedrich Feuerhake , Dorit Merhof

The histopathological analysis of whole-slide images (WSIs) is fundamental to cancer diagnosis but is a time-consuming and expert-driven process. While deep learning methods show promising results, dominant patch-based methods artificially…

Image and Video Processing · Electrical Eng. & Systems 2025-10-08 Alexander Weers , Alexander H. Berger , Laurin Lux , Peter Schüffler , Daniel Rueckert , Johannes C. Paetzold

Multimodal large-scale pretraining has shown impressive performance for unstructured data such as language and image. However, a prevalent real-world scenario involves structured data types, tabular and time-series, along with unstructured…

Machine Learning · Computer Science 2024-04-25 Sayna Ebrahimi , Sercan O. Arik , Yihe Dong , Tomas Pfister
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