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Paired image-text data with subtle variations in-between (e.g., people holding surfboards vs. people holding shovels) hold the promise of producing Vision-Language Models with proper compositional understanding. Synthesizing such training…

Computer Vision and Pattern Recognition · Computer Science 2025-04-01 Haoxin Li , Boyang Li

Recent advances in computational pathology have leveraged vision-language models to learn joint representations of Hematoxylin and Eosin (HE) images with spatial transcriptomic (ST) profiles. However, existing approaches typically align HE…

Learning causal structures from observational data remains a fundamental yet computationally intensive task, particularly in high-dimensional settings where existing methods face challenges such as the super-exponential growth of the search…

Machine Learning · Statistics 2026-02-12 Haixiang Sun , Pengchao Tian , Zihan Zhou , Jielei Zhang , Peiyi Li , Andrew L. Liu

Cross-modal medical image segmentation presents a significant challenge, as different imaging modalities produce images with varying resolutions, contrasts, and appearances of anatomical structures. We introduce compositionality as an…

Computer Vision and Pattern Recognition · Computer Science 2024-08-22 Aniek Eijpe , Valentina Corbetta , Kalina Chupetlovska , Regina Beets-Tan , Wilson Silva

Information extraction, e.g., attribute value extraction, has been extensively studied and formulated based only on text. However, many attributes can benefit from image-based extraction, like color, shape, pattern, among others. The visual…

Computation and Language · Computer Science 2023-06-05 Hejie Cui , Rongmei Lin , Nasser Zalmout , Chenwei Zhang , Jingbo Shang , Carl Yang , Xian Li

Time series visualization plays a crucial role in identifying patterns and extracting insights across various domains. However, as datasets continue to grow in size, visualizing them effectively becomes challenging. Downsampling, which…

Human-Computer Interaction · Computer Science 2023-04-04 Jonas Van Der Donckt , Jeroen Van Der Donckt , Michael Rademaker , Sofie Van Hoecke

Results: We present an application that enables the quantitative analysis of multichannel 5-D (x, y, z, t, channel) and large montage confocal fluorescence microscopy images. The image sequences show stem cells together with blood vessels,…

Contrastive learning methods in computer vision typically rely on augmented views of the same image or multimodal pretraining strategies that align paired modalities. However, these approaches often overlook semantic relationships between…

Computer Vision and Pattern Recognition · Computer Science 2026-05-11 Marta Hasny , Maxime Di Folco , Keno Bressem , Julia Schnabel

Spatially-resolved omics-data enable researchers to precisely distinguish cell types in tissue and explore their spatial interactions, enabling deep understanding of tissue functionality. To understand what causes or deteriorates a disease…

Analysts commonly investigate the data distributions derived from statistical aggregations of data that are represented by charts, such as histograms and binned scatterplots, to visualize and analyze a large-scale dataset. Aggregate queries…

Databases · Computer Science 2019-10-14 Honghui Mei , Wei Chen , Yating Wei , Yuanzhe Hu , Shuyue Zhou , Bingru Lin , Ying Zhao , Jiazhi Xia

Spatial transcriptomics (ST) provides essential spatial context by mapping gene expression within tissue, enabling detailed study of cellular heterogeneity and tissue organization. However, aligning ST data with histology images poses…

A new statistical model designed for regression analysis with a sparse design matrix is proposed. This new model utilizes the positions of the limited non-zero elements in the design matrix to decompose the regression model into…

Applications · Statistics 2022-01-17 Hsien-Wei Chen

Large amounts of data are available due to low-cost and high-capacity data storage equipments. We propose a data exploration/visualization method for tabular multi-dimensional, time-varying datasets to present selected items in their global…

Information Retrieval · Computer Science 2015-05-20 Nicolas Turenne

Spatial transcriptomics is a modern sequencing technology that allows the measurement of the activity of thousands of genes in a tissue sample and map where the activity is occurring. This technology has enabled the study of the so-called…

Methodology · Statistics 2022-09-15 Andrea Sottosanti , Davide Risso

Spatial transcriptomics (ST) technologies not only offer an unprecedented opportunity to interrogate intact biological samples in a spatially informed manner, but also set the stage for integration with other imaging-based modalities.…

Quantitative Methods · Quantitative Biology 2025-07-31 Levin M Moser , Ahmad Kamal Hamid , Esteban Miglietta , Nodar Gogoberidze , Beth A Cimini

Visual analytics have played an increasingly critical role in the Internet of Things, where massive visual signals have to be compressed and fed into machines. But facing such big data and constrained bandwidth capacity, existing…

Computer Vision and Pattern Recognition · Computer Science 2021-06-17 Yueyu Hu , Wenhan Yang , Haofeng Huang , Jiaying Liu

In recent years, data selection has emerged as a core issue for large-scale visual-language model pretraining, especially on noisy web-curated datasets. One widely adopted strategy assigns quality scores such as CLIP similarity for each…

Machine Learning · Computer Science 2024-02-06 Yiping Wang , Yifang Chen , Wendan Yan , Kevin Jamieson , Simon Shaolei Du

Point sets in 2D with multiple classes are a common type of data. A canonical visualization design for them are scatterplots, which do not scale to large collections of points. For these larger data sets, binned aggregation (or binning) is…

Human-Computer Interaction · Computer Science 2020-01-16 Florian Heimerl , Chih-Ching Chang , Alper Sarikaya , Michael Gleicher

Understanding how cellular morphology, gene expression, and spatial context jointly shape tissue function is a central challenge in biology. Image-based spatial transcriptomics technologies now provide high-resolution measurements of cell…

Quantitative Methods · Quantitative Biology 2026-02-17 Zhenglun Kong , Mufan Qiu , John Boesen , Xiang Lin , Sukwon Yun , Tianlong Chen , Manolis Kellis , Marinka Zitnik

Table structure recognition aims to extract the logical and physical structure of unstructured table images into a machine-readable format. The latest end-to-end image-to-text approaches simultaneously predict the two structures by two…

Computer Vision and Pattern Recognition · Computer Science 2023-03-21 Yongshuai Huang , Ning Lu , Dapeng Chen , Yibo Li , Zecheng Xie , Shenggao Zhu , Liangcai Gao , Wei Peng