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Related papers: TrialSynth: Generation of Synthetic Sequential Cli…

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Clinical trials face mounting challenges: fragmented patient populations, slow enrollment, and unsustainable costs, particularly for late phase trials in oncology and rare diseases. While external control arms built from real-world data…

Machine Learning · Computer Science 2025-11-21 Perrine Chassat , Van Tuan Nguyen , Lucas Ducrot , Emilie Lanoy , Agathe Guilloux

Artificial Intelligence in healthcare is a new and exciting frontier and the possibilities are endless. With deep learning approaches beating human performances in many areas, the logical next step is to attempt their application in the…

Machine Learning · Computer Science 2018-08-21 Ally Salim

The limited data availability due to strict privacy regulations and significant resource demands severely constrains biomedical time-series AI development, which creates a critical gap between data requirements and accessibility. Synthetic…

Machine Learning · Computer Science 2025-11-25 Youngjoon Lee , Seongmin Cho , Yehhyun Jo , Jinu Gong , Hyunjoo Jenny Lee , Joonhyuk Kang

Accurate and comprehensive clinical documentation is crucial for delivering high-quality healthcare, facilitating effective communication among providers, and ensuring compliance with regulatory requirements. However, manual transcription…

Computation and Language · Computer Science 2024-06-12 Anjanava Biswas , Wrick Talukdar

Recent work in synthetic data generation in the time-series domain has focused on the use of Generative Adversarial Networks. We propose a novel architecture for synthetically generating time-series data with the use of Variational…

Machine Learning · Computer Science 2021-12-08 Abhyuday Desai , Cynthia Freeman , Zuhui Wang , Ian Beaver

In modern air traffic management, generating synthetic flight trajectories has emerged as a promising solution for addressing data scarcity, protecting sensitive information, and supporting large-scale analyses. In this paper, we propose a…

Machine Learning · Computer Science 2025-04-15 Abdulmajid Murad , Massimiliano Ruocco

Synthetic medical data which preserves privacy while maintaining utility can be used as an alternative to real medical data, which has privacy costs and resource constraints associated with it. At present, most models focus on generating…

Machine Learning · Computer Science 2019-11-28 Saloni Dash , Ritik Dutta , Isabelle Guyon , Adrien Pavao , Andrew Yale , Kristin P. Bennett

The widespread adoption of electronic health records and digital healthcare data has created a demand for data-driven insights to enhance patient outcomes, diagnostics, and treatments. However, using real patient data presents privacy and…

Machine Learning · Computer Science 2023-11-15 Aryan Jadon , Shashank Kumar

Synthetic data generation is of great interest in diverse applications, such as for privacy protection. Deep generative models, such as variational autoencoders (VAEs), are a popular approach for creating such synthetic datasets from…

Machine Learning · Statistics 2021-05-17 Kiana Farhadyar , Federico Bonofiglio , Daniela Zoeller , Harald Binder

Background: Heart failure (HF) research is constrained by limited access to large, shareable datasets due to privacy regulations and institutional barriers. Synthetic data generation offers a promising solution to overcome these challenges…

The generation of virtual populations (VPs) of anatomy is essential for conducting in silico trials of medical devices. Typically, the generated VP should capture sufficient variability while remaining plausible and should reflect the…

Image and Video Processing · Electrical Eng. & Systems 2023-07-31 Haoran Dou , Nishant Ravikumar , Alejandro F. Frangi

The increasing adoption of synthetic data in aviation research offers a promising solution to data scarcity and confidentiality challenges. This study investigates the potential of generative models to produce realistic synthetic flight…

Machine Learning · Computer Science 2026-04-24 Karim Aly , Alexei Sharpanskykh

The recent availability of electronic health records (EHRs) have provided enormous opportunities to develop artificial intelligence (AI) algorithms. However, patient privacy has become a major concern that limits data sharing across…

Machine Learning · Computer Science 2023-02-01 Jin Li , Benjamin J. Cairns , Jingsong Li , Tingting Zhu

Synthetic data generation plays a crucial role in medical research by mitigating privacy concerns and enabling large-scale patient data analysis. This study presents a beta-Variational Autoencoder Graph Convolutional Neural Network…

Machine Learning · Computer Science 2025-06-18 Francesco Fabbri , Martino Andrea Scarpolini , Angelo Iollo , Francesco Viola , Francesco Tudisco

Researchers require timely access to real-world longitudinal electronic health records (EHR) to develop, test, validate, and implement machine learning solutions that improve the quality and efficiency of healthcare. In contrast, health…

Machine Learning · Computer Science 2020-12-21 Siddharth Biswal , Soumya Ghosh , Jon Duke , Bradley Malin , Walter Stewart , Jimeng Sun

This paper presents a comprehensive systematic review of generative models (GANs, VAEs, DMs, and LLMs) used to synthesize various medical data types, including imaging (dermoscopic, mammographic, ultrasound, CT, MRI, and X-ray), text,…

Synthetic financial data provides a practical solution to the privacy, accessibility, and reproducibility challenges that often constrain empirical research in quantitative finance. This paper investigates the use of deep generative models,…

Statistical Finance · Quantitative Finance 2025-12-30 Christophe D. Hounwanou , Yae Ulrich Gaba

The usage of medical image data for the training of large-scale machine learning approaches is particularly challenging due to its scarce availability and the costly generation of data annotations, typically requiring the engagement of…

Computer Vision and Pattern Recognition · Computer Science 2024-06-26 Joshua Niemeijer , Jan Ehrhardt , Hristina Uzunova , Heinz Handels

To make medical datasets accessible without sharing sensitive patient information, we introduce a novel end-to-end approach for generative de-identification of dynamic medical imaging data. Until now, generative methods have faced…

Computer Vision and Pattern Recognition · Computer Science 2024-06-04 Hadrien Reynaud , Qingjie Meng , Mischa Dombrowski , Arijit Ghosh , Thomas Day , Alberto Gomez , Paul Leeson , Bernhard Kainz

Each year, hundreds of clinical trials are conducted to evaluate new medical interventions, but sharing patient records from these trials with other institutions can be challenging due to privacy concerns and federal regulations. To help…

Machine Learning · Computer Science 2025-02-19 Trisha Das , Zifeng Wang , Afrah Shafquat , Mandis Beigi , Jason Mezey , Jacob Aptekar , Jimeng Sun
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