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The rapid digitization of real-world data presents an unprecedented opportunity to optimize healthcare delivery and accelerate biomedical discovery. However, these data are often found in unstructured forms such as clinical notes in…

We propose RareGraph-Synth, a knowledge-guided, continuous-time diffusion framework that generates realistic yet privacy-preserving synthetic electronic-health-record (EHR) trajectories for ultra-rare diseases. RareGraph-Synth unifies five…

Machine Learning · Computer Science 2025-10-09 Khartik Uppalapati , Shakeel Abdulkareem , Bora Yimenicioglu

We present an empirical evaluation of fMRI data augmentation via synthesis. For synthesis we use generative mod-els trained on real neuroimaging data to produce novel task-dependent functional brain images. Analyzed generative mod-els…

Computer Vision and Pattern Recognition · Computer Science 2019-07-16 Peiye Zhuang , Alexander G. Schwing , Sanmi Koyejo

Benchmarking anomaly detection approaches for multivariate time series is a challenging task due to a lack of high-quality datasets. Current publicly available datasets are too small, not diverse and feature trivial anomalies, which hinders…

Machine Learning · Computer Science 2025-11-13 Lucas Correia , Jan-Christoph Goos , Thomas Bäck , Anna V. Kononova

This article describes techniques employed in the production of a synthetic dataset of driver telematics emulated from a similar real insurance dataset. The synthetic dataset generated has 100,000 policies that included observations about…

Machine Learning · Statistics 2021-02-02 Banghee So , Jean-Philippe Boucher , Emiliano A. Valdez

Sharing data from clinical studies can facilitate innovative data-driven research and ultimately lead to better public health. However, sharing biomedical data can put sensitive personal information at risk. This is usually solved by…

Due to the limited availability of anomaly examples, video anomaly detection is often seen as one-class classification (OCC) problem. A popular way to tackle this problem is by utilizing an autoencoder (AE) trained only on normal data. At…

Computer Vision and Pattern Recognition · Computer Science 2021-10-20 Marcella Astrid , Muhammad Zaigham Zaheer , Seung-Ik Lee

Many decisions in healthcare, business, and other policy domains are made without the support of rigorous evidence due to the cost and complexity of performing randomized experiments. Using observational data to answer causal questions is…

Machine Learning · Statistics 2017-11-02 Alejandro Schuler , Ken Jung , Robert Tibshirani , Trevor Hastie , Nigam Shah

Adversarial scenario generation is a cost-effective approach for safety assessment of autonomous driving systems. However, existing methods are often constrained to a single, fixed trade-off between competing objectives such as…

Artificial Intelligence · Computer Science 2026-05-06 Tong Nie , Yuewen Mei , Yihong Tang , Junlin He , Jie Sun , Haotian Shi , Wei Ma , Jian Sun

Time series (TS) data have consistently been in short supply, yet their demand remains high for training systems in prediction, modeling, classification, and various other applications. Synthesis can serve to expand the sample population,…

Signal Processing · Electrical Eng. & Systems 2024-04-23 Tracey K. M. Lee , H. W. Chan , K. H. Leo , Effie Chew , L. Zhao , Saeid Sanei

Variational autoencoders (VAEs) are deep probabilistic models that are used in scientific applications. Many works try to mitigate this problem from the probabilistic methods perspective by new inference techniques or training procedures.…

Machine Learning · Statistics 2024-12-24 Tim Z. Xiao , Johannes Zenn , Robert Bamler

Pretraining robust vision or multimodal foundation models (e.g., CLIP) relies on large-scale datasets that may be noisy, potentially misaligned, and have long-tail distributions. Previous works have shown promising results in augmenting…

Computer Vision and Pattern Recognition · Computer Science 2024-10-17 Qingqing Cao , Mahyar Najibi , Sachin Mehta

While generative models have shown great success in generating high-dimensional samples conditional on low-dimensional descriptors (learning e.g. stroke thickness in MNIST, hair color in CelebA, or speaker identity in Wavenet), their…

Machine Learning · Computer Science 2019-10-31 Mohammad Lotfollahi , Mohsen Naghipourfar , Fabian J. Theis , F. Alexander Wolf

Sharing medical data for machine learning model training purposes is often impossible due to the risk of disclosing identifying information about individual patients. Synthetic data produced by generative artificial intelligence (genAI)…

Machine Learning · Computer Science 2026-02-12 Rustam Zhumagambetov , Niklas Giesa , Sebastian D. Boie , Stefan Haufe

Population synthesis is concerned with the generation of synthetic yet realistic representations of populations. It is a fundamental problem in the modeling of transport where the synthetic populations of micro-agents represent a key input…

Machine Learning · Statistics 2019-07-19 Stanislav S. Borysov , Jeppe Rich , Francisco C. Pereira

We present a VAE architecture for encoding and generating high dimensional sequential data, such as video or audio. Our deep generative model learns a latent representation of the data which is split into a static and dynamic part, allowing…

Machine Learning · Computer Science 2018-06-13 Yingzhen Li , Stephan Mandt

Acquiring large quantities of data and annotations is known to be effective for developing high-performing deep learning models, but is difficult and expensive to do in the healthcare context. Adding synthetic training data using generative…

Image and Video Processing · Electrical Eng. & Systems 2023-10-06 Menghan Yu , Sourabh Kulhare , Courosh Mehanian , Charles B Delahunt , Daniel E Shea , Zohreh Laverriere , Ishan Shah , Matthew P Horning

Generating realistic training data for supervised learning remains a significant challenge in artificial intelligence, particularly in domains where large, expert-labeled datasets are scarce or costly to obtain. This is especially true for…

Machine Learning · Computer Science 2026-03-20 Yakir Yehuda , Kira Radinsky

Individual-level data (microdata) that characterizes a population, is essential for studying many real-world problems. However, acquiring such data is not straightforward due to cost and privacy constraints, and access is often limited to…

Machine Learning · Computer Science 2022-12-13 Angeela Acharya , Siddhartha Sikdar , Sanmay Das , Huzefa Rangwala

Data preprocessing is a critical part of time series data analysis. Data from connected medical devices often have missing or abnormal values during acquisition. Handling such situations requires additional assumptions and domain knowledge.…

Signal Processing · Electrical Eng. & Systems 2025-12-16 Ali AbuSaleh , Mehdi Rahim
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