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With large volumes of health care data comes the research area of computational phenotyping, making use of techniques such as machine learning to describe illnesses and other clinical concepts from the data itself. The "traditional"…

Machine Learning · Statistics 2016-12-30 Chris Hodapp

Subsampling is one of the popular methods to balance statistical efficiency and computational efficiency in the big data era. Most approaches aim at selecting informative or representative sample points to achieve good overall information…

Methodology · Statistics 2024-07-10 Haolin Chen , Holger Dette , Jun Yu

The alignment of biological sequences such as DNA, RNA, and proteins, is one of the basic tools that allow to detect evolutionary patterns, as well as functional/structural characterizations between homologous sequences in different…

Quantitative Methods · Quantitative Biology 2023-05-01 Louise Budzynski , Andrea Pagnani

In recent years the importance of finding a meaningful pattern from huge datasets has become more challenging. Data miners try to adopt innovative methods to face this problem by applying feature selection methods. In this paper we propose…

Machine Learning · Computer Science 2014-03-11 Mehdi Naseriparsa , Amir-masoud Bidgoli , Touraj Varaee

Fine-tuning large language models (LLMs) with limited data poses a practical challenge in low-resource languages, specialized domains, and constrained deployment settings. While pre-trained LLMs provide strong foundations, effective…

Computation and Language · Computer Science 2025-10-29 Marton Szep , Daniel Rueckert , Rüdiger von Eisenhart-Rothe , Florian Hinterwimmer

We investigate Learning from Label Proportions (LLP), a partial information setting where examples in a training set are grouped into bags, and only aggregate label values in each bag are available. Despite the partial observability, the…

Machine Learning · Computer Science 2025-06-02 Robert Busa-Fekete , Travis Dick , Claudio Gentile , Haim Kaplan , Tomer Koren , Uri Stemmer

Background: Single-cell RNA sequencing (scRNA-seq) yields valuable insights about gene expression and gives critical information about complex tissue cellular composition. In the analysis of single-cell RNA sequencing, the annotations of…

Genomics · Quantitative Biology 2023-03-29 Xiaowen Cao , Li Xing , Elham Majd , Hua He , Junhua Gu , Xuekui Zhang

Supervised learning from training data with imbalanced class sizes, a commonly encountered scenario in real applications such as anomaly/fraud detection, has long been considered a significant challenge in machine learning. Motivated by…

Machine Learning · Computer Science 2019-05-27 Yunru Liu , Tingran Gao , Haizhao Yang

We cover how to determine a sufficiently large sample size for a $K$-armed randomized experiment in order to estimate conditional counterfactual expectations in data-driven subgroups. The sub-groups can be output by any feature space…

Machine Learning · Computer Science 2024-03-08 Gabriel Ruiz

Supervised learning-based segmentation methods typically require a large number of annotated training data to generalize well at test time. In medical applications, curating such datasets is not a favourable option because acquiring a large…

Image and Video Processing · Electrical Eng. & Systems 2020-11-20 Krishna Chaitanya , Neerav Karani , Christian F. Baumgartner , Ertunc Erdil , Anton Becker , Olivio Donati , Ender Konukoglu

Feature matching and finding correspondences between endoscopic images is a key step in many clinical applications such as patient follow-up and generation of panoramic image from clinical sequences for fast anomalies localization.…

Computer Vision and Pattern Recognition · Computer Science 2022-08-25 Manel Farhat , Houda Chaabouni-Chouayakh , Achraf Ben-Hamadou

This paper targets the question of predicting machine learning classification model performance, when taking into account the number of training examples per class and not just the overall number of training examples. This leads to the a…

Machine Learning · Computer Science 2024-03-12 Thomas Mühlenstädt , Jelena Frtunikj

Self-supervised learning (SSL) has proven vital in speech and audio-related applications. The paradigm trains a general model on unlabeled data that can later be used to solve specific downstream tasks. This type of model is costly to train…

As the size and richness of available datasets grow larger, the opportunities for solving increasingly challenging problems with algorithms learning directly from data grow at the same pace. Consequently, the capability of learning…

Machine Learning · Computer Science 2019-12-13 Raffaello Camoriano

Leverage score sampling provides an appealing way to perform approximate computations for large matrices. Indeed, it allows to derive faithful approximations with a complexity adapted to the problem at hand. Yet, performing leverage scores…

Machine Learning · Statistics 2019-01-25 Alessandro Rudi , Daniele Calandriello , Luigi Carratino , Lorenzo Rosasco

Subsampling methods aim to select a subsample as a surrogate for the observed sample. As a powerful technique for large-scale data analysis, various subsampling methods are developed for more effective coefficient estimation and model…

Methodology · Statistics 2021-05-05 Tao Li , Cheng Meng

Biomedical researchers usually study the effects of certain exposures on disease risks among a well-defined population. To achieve this goal, the gold standard is to design a trial with an appropriate sample from that population. Due to the…

Applications · Statistics 2019-11-18 Cheng Zheng , Sayan Dasgupta , Yuxiang Xie , Asad Haris , Ying Qing Chen

Purpose: The aim of this work is to develop a neural network training framework for continual training of small amounts of medical imaging data and create heuristics to assess training in the absence of a hold-out validation or test set.…

Image and Video Processing · Electrical Eng. & Systems 2023-09-27 Sohaib Naim , Brian Caffo , Haris I Sair , Craig K Jones

Deep learning owes its success to three key factors: scale of data, enhanced models to learn representations from data, and scale of computation. This book chapter presented the importance of the data-driven approach to learn good…

Computer Vision and Pattern Recognition · Computer Science 2017-08-01 Chun-Nan Chou , Chuen-Kai Shie , Fu-Chieh Chang , Jocelyn Chang , Edward Y. Chang

Deep learning demands a huge amount of well-labeled data to train the network parameters. How to use the least amount of labeled data to obtain the desired classification accuracy is of great practical significance, because for many…

Machine Learning · Computer Science 2019-12-20 Xiao Han , Zihao Wang , Enmei Tu , Gunnam Suryanarayana , Jie Yang