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miRNA and gene expression profiles have been proved useful for classifying cancer samples. Efficient classifiers have been recently sought and developed. A number of attempts to classify cancer samples using miRNA/gene expression profiles…

Computational Engineering, Finance, and Science · Computer Science 2014-01-21 Rania Ibrahim , Noha A. Yousri , Mohamed A. Ismail , Nagwa M. El-Makky

Traditionally, convolutional neural networks need large amounts of data labelled by humans to train. Self supervision has been proposed as a method of dealing with small amounts of labelled data. The aim of this study is to determine…

Image and Video Processing · Electrical Eng. & Systems 2020-11-23 Nicolas Ewen , Naimul Khan

An overarching goal in machine learning is to build a generalizable model with few samples. To this end, overparameterization has been the subject of immense interest to explain the generalization ability of deep nets even when the size of…

Machine Learning · Computer Science 2022-01-19 Yue Sun , Adhyyan Narang , Halil Ibrahim Gulluk , Samet Oymak , Maryam Fazel

Mini-batch stochastic gradient descent and variants thereof have become standard for large-scale empirical risk minimization like the training of neural networks. These methods are usually used with a constant batch size chosen by simple…

Machine Learning · Computer Science 2017-06-29 Lukas Balles , Javier Romero , Philipp Hennig

Finding the optimal learning rate for language model pretraining is a challenging task. This is not only because there is a complicated correlation between learning rate, batch size, number of training tokens, model size, and other…

Computation and Language · Computer Science 2024-09-13 Yikang Shen , Matthew Stallone , Mayank Mishra , Gaoyuan Zhang , Shawn Tan , Aditya Prasad , Adriana Meza Soria , David D. Cox , Rameswar Panda

Subsampling methods aim to select a subsample as a surrogate for the observed sample. Such methods have been used pervasively in large-scale data analytics, active learning, and privacy-preserving analysis in recent decades. Instead of…

Machine Learning · Statistics 2022-06-03 Jingyi Zhang , Cheng Meng , Jun Yu , Mengrui Zhang , Wenxuan Zhong , Ping Ma

Background: Understanding the relationship between the Omics and the phenotype is a central problem in precision medicine. The high dimensionality of metabolomics data challenges learning algorithms in terms of scalability and…

Big data sets must be carefully partitioned into statistically similar data subsets that can be used as representative samples for big data analysis tasks. In this paper, we propose the random sample partition (RSP) data model to represent…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-06-11 Salman Salloum , Yulin He , Joshua Zhexue Huang , Xiaoliang Zhang , Tamer Z. Emara , Chenghao Wei , Heping He

In a clinical trial, the random allocation aims to balance prognostic factors between arms, preventing true confounders. However, residual differences due to chance may introduce near-confounders. Adjusting on prognostic factors is…

Methodology · Statistics 2024-11-18 Joe de Keizer , Rémi Lenain , Raphaël Porcher , Sarah Zoha , Arthur Chatton , Yohann Foucher

Current 3D semi-supervised segmentation methods face significant challenges such as limited consideration of contextual information and the inability to generate reliable pseudo-labels for effective unsupervised data use. To address these…

Computer Vision and Pattern Recognition · Computer Science 2023-11-22 Sanaz Karimijafarbigloo , Reza Azad , Yury Velichko , Ulas Bagci , Dorit Merhof

Effective convolutional neural networks are trained on large sets of labeled data. However, creating large labeled datasets is a very costly and time-consuming task. Semi-supervised learning uses unlabeled data to train a model with higher…

Computer Vision and Pattern Recognition · Computer Science 2016-06-16 Mehdi Sajjadi , Mehran Javanmardi , Tolga Tasdizen

In biological research machine learning algorithms are part of nearly every analytical process. They are used to identify new insights into biological phenomena, interpret data, provide molecular diagnosis for diseases and develop…

Advances in data collecting technologies in genomics have significantly increased the need for tools designed to study the genetic basis of many diseases. Effective statistical methods should excel in both prediction accuracy and biomarker…

Methodology · Statistics 2025-11-13 Anthony-Alexander Christidis , Stefan Van Aelst , Ruben Zamar

The generative large language models (LLMs) are increasingly used for data augmentation tasks, where text samples are paraphrased (or generated anew) and then used for classifier fine-tuning. Existing works on augmentation leverage the…

Computation and Language · Computer Science 2024-10-15 Jan Cegin , Branislav Pecher , Jakub Simko , Ivan Srba , Maria Bielikova , Peter Brusilovsky

Almost every software system provides configuration options to tailor the system to the target platform and application scenario. Often, this configurability renders the analysis of every individual system configuration infeasible. To…

Software Engineering · Computer Science 2016-02-17 Flávio Medeiros , Christian Kästner , Márcio Ribeiro , Rohit Gheyi , Sven Apel

It has been found that stochastic algorithms often find good solutions much more rapidly than inherently-batch approaches. Indeed, a very useful rule of thumb is that often, when solving a machine learning problem, an iterative technique…

Machine Learning · Computer Science 2013-08-19 Andrew Cotter

Instruction tuning improves the ability of large language models (LLMs) to follow diverse human instructions, but achieving strong performance on specific target tasks remains challenging. A critical bottleneck is selecting the most…

Machine Learning · Computer Science 2025-05-19 Da Ma , Gonghu Shang , Zhi Chen , Libo Qin , Yijie Luo , Lei Pan , Shuai Fan , Lu Chen , Kai Yu

Supervised classifying of biological samples based on genetic information, (e.g. gene expression profiles) is an important problem in biostatistics. In order to find both accurate and interpretable classification rules variable selection is…

Methodology · Statistics 2012-08-09 Bernd Klaus

Motivation: Assigning RNA-seq reads to their transcript of origin is a fundamental task in transcript expression estimation. Where ambiguities in assignments exist due to transcripts sharing sequence, e.g. alternative isoforms or alleles,…

Quantitative Methods · Quantitative Biology 2015-07-01 James Hensman , Panagiotis Papastamoulis , Peter Glaus , Antti Honkela , Magnus Rattray

In today's modern era of Big data, computationally efficient and scalable methods are needed to support timely insights and informed decision making. One such method is sub-sampling, where a subset of the Big data is analysed and used as…

Methodology · Statistics 2022-09-07 Amalan Mahendran , Helen Thompson , James M. McGree
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