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Recent breakthroughs in self-supervised learning have enabled the use of large unlabeled datasets to train visual foundation models that can generalize to a variety of downstream tasks. While this training paradigm is well suited for the…

Foundation models (FMs) are transforming computational pathology by offering new ways to analyze histopathology images. However, FMs typically require weeks of training on large databases, making their creation a resource-intensive process.…

Image and Video Processing · Electrical Eng. & Systems 2026-01-27 Till Nicke , Daniela Schacherer , Jan Raphael Schäfer , Natalia Artysh , Antje Prasse , André Homeyer , Andrea Schenk , Henning Höfener , Johannes Lotz

Foundation models pretrained on large-scale pathology datasets have shown promising results across various diagnostic tasks. Here, we present a systematic evaluation of transfer learning strategies for brain tumor classification using these…

Image and Video Processing · Electrical Eng. & Systems 2025-04-09 Ken Enda , Yoshitaka Oda , Zen-ichi Tanei , Kenichi Satoh , Hiroaki Motegi , Terasaka Shunsuke , Shigeru Yamaguchi , Takahiro Ogawa , Wang Lei , Masumi Tsuda , Shinya Tanaka

Tissue phenotyping is a fundamental computational pathology (CPath) task in learning objective characterizations of histopathologic biomarkers in anatomic pathology. However, whole-slide imaging (WSI) poses a complex computer vision problem…

Foundation models for computational pathology are expected to facilitate the development of high-performing, generalisable deep learning systems. However, in addition to biologically relevant features, current foundation models also capture…

Recently, deep neural networks have greatly advanced histopathology image segmentation but usually require abundant annotated data. However, due to the gigapixel scale of whole slide images and pathologists' heavy daily workload, obtaining…

Computer Vision and Pattern Recognition · Computer Science 2023-03-13 Wentao Pan , Jiangpeng Yan , Hanbo Chen , Jiawei Yang , Zhe Xu , Xiu Li , Jianhua Yao

In recent years, a standard computational pathology workflow has emerged where whole slide images are cropped into tiles, these tiles are processed using a foundation model, and task-specific models are built using the resulting…

Computer Vision and Pattern Recognition · Computer Science 2026-02-26 Eric Zimmermann , Julian Viret , Michal Zelechowski , James Brian Hall , Neil Tenenholtz , Adam Casson , George Shaikovski , Eugene Vorontsov , Siqi Liu , Kristen A Severson

Foundation models are reshaping computational pathology by enabling transfer learning, where models pre-trained on vast datasets can be adapted for downstream diagnostic, prognostic, and therapeutic response tasks. Despite these advances,…

Masking strategies commonly employed in natural language processing are still underexplored in vision tasks such as concept learning, where conventional methods typically rely on full images. However, using masked images diversifies…

Computer Vision and Pattern Recognition · Computer Science 2025-11-14 Yuwei Sun , Lu Mi , Ippei Fujisawa , Ruiqiao Mei , Jimin Chen , Siyu Zhu , Ryota Kanai

Foundation models pretrained on large-scale datasets are revolutionizing the field of computational pathology (CPath). The generalization ability of foundation models is crucial for the success in various downstream clinical tasks. However,…

Foundation models are trained on massive amounts of data to distinguish complex patterns and can be adapted to a wide range of downstream tasks with minimal computational resources. Here, we develop a foundation model for prostate cancer…

Image and Video Processing · Electrical Eng. & Systems 2024-11-25 Joona Pohjonen , Abderrahim-Oussama Batouche , Antti Rannikko , Kevin Sandeman , Andrew Erickson , Esa Pitkanen , Tuomas Mirtti

Foundation models constitute a significant advancement in computer vision: after a single, albeit costly, training phase, they can address a wide array of tasks. In the field of Earth observation, over 75 remote sensing vision foundation…

Computer Vision and Pattern Recognition · Computer Science 2025-05-07 Pierre Adorni , Minh-Tan Pham , Stéphane May , Sébastien Lefèvre

Ultrasound imaging is widely used in clinical practice due to its cost-effectiveness, mobility, and safety. However, current AI research often treats disease prediction and tissue segmentation as two separate tasks and their model requires…

Image and Video Processing · Electrical Eng. & Systems 2026-03-10 Zhi Chen , Le Zhang

To handle the large scale of whole slide images in computational pathology, most approaches first tessellate the images into smaller patches, extract features from these patches, and finally aggregate the feature vectors with…

Computer Vision and Pattern Recognition · Computer Science 2025-03-05 Benedikt Roth , Valentin Koch , Sophia J. Wagner , Julia A. Schnabel , Carsten Marr , Tingying Peng

This paper presents a new regularization method to train a fully convolutional network for semantic tissue segmentation in histopathological images. This method relies on the benefit of unsupervised learning, in the form of image…

Computer Vision and Pattern Recognition · Computer Science 2020-11-26 C. T. Sari , C. Sokmensuer , C. Gunduz-Demir

Artificial Intelligence (AI) has great potential to improve health outcomes by training systems on vast digitized clinical datasets. Computational Pathology, with its massive amounts of microscopy image data and impact on diagnostics and…

Image and Video Processing · Electrical Eng. & Systems 2024-05-24 Gabriele Campanella , Eugene Fluder , Jennifer Zeng , Chad Vanderbilt , Thomas J. Fuchs

The state of the art on many NLP tasks is currently achieved by large pre-trained language models, which require a considerable amount of computation. We explore a setting where many different predictions are made on a single piece of text.…

Computation and Language · Computer Science 2020-04-30 Jingfei Du , Myle Ott , Haoran Li , Xing Zhou , Veselin Stoyanov

Computational pathology, which involves analyzing whole slide images for automated cancer diagnosis, relies on multiple instance learning, where performance depends heavily on the feature extractor and aggregator. Recent Pathology…

Computer Vision and Pattern Recognition · Computer Science 2025-05-22 Conghao Xiong , Hao Chen , Joseph J. Y. Sung

Text-to-image personalization aims to teach a pre-trained diffusion model to reason about novel, user provided concepts, embedding them into new scenes guided by natural language prompts. However, current personalization approaches struggle…

Computer Vision and Pattern Recognition · Computer Science 2023-03-07 Rinon Gal , Moab Arar , Yuval Atzmon , Amit H. Bermano , Gal Chechik , Daniel Cohen-Or

Diagnosing and treating skin diseases require advanced visual skills across domains and the ability to synthesize information from multiple imaging modalities. While current deep learning models excel at specific tasks like skin cancer…

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