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Deep Brain Stimulation (DBS) is a highly effective treatment for Parkinson's Disease (PD). Recent research uses reinforcement learning (RL) for DBS, with RL agents modulating the stimulation frequency and amplitude. But, these models rely…

Machine Learning · Computer Science 2025-10-07 Nicholas Carter , Arkaprava Gupta , Prateek Ganguli , Benedikt Dietrich , Vibhor Krishna , Samarjit Chakraborty

Markerless motion capture has become an active field of research in computer vision in recent years. Its extensive applications are known in a great variety of fields, including computer animation, human motion analysis, biomedical…

Computer Vision and Pattern Recognition · Computer Science 2022-01-10 Doan Duy Vo , Russell Butler

Parkinson's Disease (PD) is one of the most prevalent neurodegenerative diseases that affects tens of millions of Americans. PD is highly progressive and heterogeneous. Quite a few studies have been conducted in recent years on predictive…

Computer Vision and Pattern Recognition · Computer Science 2019-05-08 Xi Sheryl Zhang , Lifang He , Kun Chen , Yuan Luo , Jiayu Zhou , Fei Wang

Bradykinesia, characterized by involuntary slowing or decrement of movement, is a fundamental symptom of Parkinson's Disease (PD) and is vital for its clinical diagnosis. Despite various methodologies explored to quantify bradykinesia,…

Computer Vision and Pattern Recognition · Computer Science 2024-04-02 Youngseo Cho , In Hee Kwak , Dohyeon Kim , Jinhee Na , Hanjoo Sung , Jeongjae Lee , Young Eun Kim , Hyeo-il Ma

This paper presents the results of our recent work on studying the effects of deep brain stimulation (DBS) and medication on the dynamics of brain local field potential (LFP) signals used for behavior analysis of patients with Parkinson s…

Neurons and Cognition · Quantitative Biology 2018-04-11 Hosein M. Golshan , Adam O. Hebb , Joshua Nedrud , Mohammad H. Mahoor

In many clinical trials studying neurodegenerative diseases such as Parkinson's disease (PD), multiple longitudinal outcomes are collected to fully explore the multidimensional impairment caused by this disease. If the outcomes deteriorate…

Applications · Statistics 2017-05-18 Jue Wang , Sheng Luo , Liang Li

Parkinson's disease (PD) presents a growing global challenge, affecting over 10 million individuals, with prevalence expected to double by 2040. Early diagnosis remains difficult due to the late emergence of motor symptoms and limitations…

Machine Learning · Computer Science 2025-10-21 Arianna Francesconi , Donato Cappetta , Fabio Rebecchi , Paolo Soda , Valerio Guarrasi , Rosa Sicilia

In chronic pain rehabilitation, physiotherapists adapt physical activity to patients' performance based on their expression of protective behavior, gradually exposing them to feared but harmless and essential everyday activities. As…

Human-Computer Interaction · Computer Science 2021-04-02 Chongyang Wang , Temitayo A. Olugbade , Akhil Mathur , Amanda C. De C. Williams , Nicholas D. Lane , Nadia Bianchi-Berthouze

Parkinson's disease (PD) has been found to affect 1 out of every 1000 people, being more inclined towards the population above 60 years. Leveraging wearable-systems to find accurate biomarkers for diagnosis has become the need of the hour,…

Machine Learning · Computer Science 2023-04-20 Poojaa C , John Sahaya Rani Alex

Parkinson's disease (PD) is debilitating, progressive, and clinically marked by motor symptoms. As the second most common neurodegenerative disease in the world, it affects over 10 million lives globally. Existing diagnoses methods have…

Machine Learning · Computer Science 2021-11-30 Riya Tyagi , Tanish Tyagi , Ming Wang , Lujin Zhang

Essential Tremor is the most common neurological movement disorder. This progressive disease causes uncontrollable rhythmic motions -most often affecting the patient's dominant upper extremity- that occur during volitional movement and make…

Neurons and Cognition · Quantitative Biology 2017-06-02 Jeffrey A. Herron , Margaret C. Thompson , Timothy Brown , Howard J. Chizeck , Jeffrey G. Ojemann , Andrew L. Ko

We present a virtual reality (VR) experience that creates a research-grade benchmark in assessing patients with active upper-limb tremor, while simultaneously offering the opportunity for patients to engage with VR experiences without their…

This paper concerns the fully automatic direct in vivo measurement of active and passive dynamic skeletal muscle states using ultrasound imaging. Despite the long standing medical need (myopathies, neuropathies, pain, injury, ageing),…

Computer Vision and Pattern Recognition · Computer Science 2017-06-30 Ryan J. Cunningham , Peter J. Harding , Ian D. Loram

We focus on the problem of estimating human hand-tremor frequency from input RGB video data. Estimating tremors from video is important for non-invasive monitoring, analyzing and diagnosing patients suffering from motor-disorders such as…

Computer Vision and Pattern Recognition · Computer Science 2018-09-11 Silvia L. Pintea , Jian Zheng , Xilin Li , Paulina J. M. Bank , Jacobus J. van Hilten , Jan C. van Gemert

A widely used test for the diagnosis of Parkinson's disease (PD) and Essential tremor (ET) is hand-drawn shapes,where the analysis is observationally performed by the examining neurologist. This method is subjective and is prone to bias…

Computer Vision and Pattern Recognition · Computer Science 2020-06-23 Nabeel Seedat , Vered Aharonson , Ilana Schlesinger

Early prediction of cerebral palsy is essential as it leads to early treatment and monitoring. Deep learning has shown promising results in biomedical engineering thanks to its capacity of modelling complicated data with its non-linear…

Computer Vision and Pattern Recognition · Computer Science 2021-06-09 Manli Zhu , Qianhui Men , Edmond S. L. Ho , Howard Leung , Hubert P. H. Shum

This paper presents an efficient deep neural network model for diagnosing Parkinson's disease from gait. More specifically, we introduce a hybrid ConvNet-Transformer architecture to accurately diagnose the disease by detecting the severity…

Computer Vision and Pattern Recognition · Computer Science 2023-11-07 Safwen Naimi , Wassim Bouachir , Guillaume-Alexandre Bilodeau

Accurate early diagnosis and monitoring of neurodegenerative conditions is essential for effective disease management and delivery of medication and treatment. This research develops automatic methods for detecting brain imaging preclinical…

Neural and Evolutionary Computing · Computer Science 2019-10-15 Amir Dehsarvi , Stephen L. Smith

Deep brain stimulation (DBS) is an advanced surgical treatment for the symptoms of Parkinson's disease (PD), involving electrical stimulation of neurons within the basal ganglia region of the brain. DBS is traditionally delivered in an…

Systems and Control · Electrical Eng. & Systems 2025-06-19 Cédric Join , Jakub Orłowski , Antoine Chaillet , Madeleine Lowery , Hugues Mounier , Michel Fliess

There is a growing interest in using pose estimation algorithms for video-based assessment of Bradykinesia in Parkinson's Disease (PD) to facilitate remote disease assessment and monitoring. However, the accuracy of pose estimation…

Computer Vision and Pattern Recognition · Computer Science 2023-08-29 Gabriela T. Acevedo Trebbau , Andrea Bandini , Diego L. Guarin