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Oculomotor alterations constitute a promising biomarker to detect and characterize Parkinson's disease (PD), even in prodromal stages. Currently, only global and simplified eye movement trajectories are employed to approximate the complex…

Computer Vision and Pattern Recognition · Computer Science 2025-02-26 Juan Niño , Luis Guayacán , Santiago Gómez , Fabio Martínez

Drug-induced parkinsonism affects many older adults with dementia, often causing gait disturbances. New advances in vision-based human pose-estimation have opened possibilities for frequent and unobtrusive analysis of gait in residential…

Computer Vision and Pattern Recognition · Computer Science 2021-10-05 Andrea Sabo , Sina Mehdizadeh , Andrea Iaboni , Babak Taati

There is great interest in developing radiological classifiers for diagnosis, staging, and predictive modeling in progressive diseases such as Parkinson's disease (PD), a neurodegenerative disease that is difficult to detect in its early…

Fundamental knowledge in activity recognition of individuals with motor disorders such as Parkinson's disease (PD) has been primarily limited to detection of steady-state/static tasks (sitting, standing, walking). To date, identification of…

Signal Processing · Electrical Eng. & Systems 2021-10-13 Mahdieh Kazemimoghadam , Nicholas P. Fey

Parkinson's disease (PD) is a neurodegenerative condition characterized by notable motor and non-motor manifestations. The assessment tool known as the Unified Parkinson's Disease Rating Scale (UPDRS) plays a crucial role in evaluating the…

Sound · Computer Science 2025-02-14 Arman Mohammadigilani , Hani Attar , Hamidreza Ehsani Chimeh , Mostafa Karami

This paper presents a new method for medical diagnosis of neurodegenerative diseases, such as Parkinson's, by extracting and using latent information from trained Deep convolutional, or convolutional-recurrent Neural Networks (DNNs). In…

Machine Learning · Computer Science 2019-01-24 Ilianna Kollia , Andreas-Georgios Stafylopatis , Stefanos Kollias

In this paper, an explainable deep learning-based classifier based on adaptive sinc filters for Parkinson's Disease diagnosis (PD) along with determining its severity, based on analyzing the gait cycle (SincPD) is presented. Considering the…

Signal Processing · Electrical Eng. & Systems 2025-02-26 Armin Salimi-Badr , Mahan Veisi , Sadra Berangi

Parkinson's Disease (PD) is a progressive neurodegenerative disorder that significantly impacts both motor and non-motor functions, including speech. Early and accurate recognition of PD through speech analysis can greatly enhance patient…

Numerical Analysis · Mathematics 2024-07-24 Niloofar Fadavi , Nazanin Fadavi

Parkinson's disease (PD) is a progressive neurodegenerative disorder that, in addition to directly impairing functional mobility, is frequently associated with vocal impairments such as hypophonia and dysarthria, which typically manifest in…

Recording muscle tendon junction displacements during movement, allows separate investigation of the muscle and tendon behaviour, respectively. In order to provide a fully-automatic tracking method, we employ a novel deep learning approach…

Quantitative Methods · Quantitative Biology 2020-09-09 Christoph Leitner , Robert Jarolim , Andreas Konrad , Annika Kruse , Markus Tilp , Jörg Schröttner , Christian Baumgartner

Isolated REM sleep behavior disorder (iRBD) is a key prodromal marker of Parkinson's disease (PD), and video-polysomnography (vPSG) remains the diagnostic gold standard. However, manual sleep staging is particularly challenging in…

Objective: The aim of this study is to develop a smartphone-based high-frequency remote monitoring platform, assess its feasibility for remote monitoring of symptoms in Parkinson's disease, and demonstrate the value of data collected using…

Computers and Society · Computer Science 2016-01-06 Andong Zhan , Max A. Little , Denzil A. Harris , Solomon O. Abiola , E. Ray Dorsey , Suchi Saria , Andreas Terzis

Parkinson's disease (PD) poses challenges in diagnosis and monitoring due to its progressive nature and complex symptoms. This study introduces a novel approach utilizing surface electromyography (sEMG) to objectively assess PD severity,…

Early and accurate identification of parkinsonian syndromes (PS) involving presynaptic degeneration from non-degenerative variants such as Scans Without Evidence of Dopaminergic Deficit (SWEDD) and tremor disorders, is important for…

Applications · Statistics 2017-03-07 R. Prashanth , Sumantra Dutta Roy , Pravat K. Mandal , Shantanu Ghosh

In this work, the issue of Parkinson's disease (PD) diagnostics using non-invasive antemortem techniques was tackled. A deep learning approach for classification of raw speech recordings in patients with diagnosed PD was proposed. The core…

Computation and Language · Computer Science 2022-04-28 Maurycy Chronowski , Maciej Klaczynski , Malgorzata Dec-Cwiek , Karolina Porebska

Resting-state EEG (rs-EEG) has been demonstrated to aid in Parkinson's disease (PD) diagnosis. In particular, the power spectral density (PSD) of low-frequency bands ({\delta} and {\theta}) and high-frequency bands ({\alpha} and \b{eta})…

Signal Processing · Electrical Eng. & Systems 2023-03-03 Anna Kurbatskaya , Alberto Jaramillo-Jimenez , John Fredy Ochoa-Gomez , Kolbjørn Brønnick , Alvaro Fernandez-Quilez

Parkinson's disease (PD) is a neurological disorder that has a variety of observable motor-related symptoms such as slow movement, tremor, muscular rigidity, and impaired posture. PD is typically diagnosed by evaluating the severity of…

Computer Vision and Pattern Recognition · Computer Science 2022-07-04 Mark Endo , Kathleen L. Poston , Edith V. Sullivan , Li Fei-Fei , Kilian M. Pohl , Ehsan Adeli

Parkinson's disease (PD) is a neurodegenerative condition characterized by frequently changing motor symptoms, necessitating continuous symptom monitoring for more targeted treatment. Classical time series classification and deep learning…

Machine Learning · Computer Science 2025-06-03 Cedric Donié , Neha Das , Satoshi Endo , Sandra Hirche

Background: Parkinson's disease (PD) is a prevalent long-term neurodegenerative disease. Though the diagnostic criteria of PD are relatively well defined, the current medical imaging diagnostic procedures are expertise-demanding, and thus…

Quantitative Methods · Quantitative Biology 2019-02-27 Jiahang Xu , Fangyang Jiao , Yechong Huang , Xinzhe Luo , Qian Xu , Ling Li , Xueling Liu , Chuantao Zuo , Ping Wu , Xiahai Zhuang

Parkinsons disease (PD) is a movement disorder and the second most common neurodengerative disease but despite its relative abundance, there are no clinically accepted neuroimaging biomarkers to make prognostic predictions or differentiate…

Neurons and Cognition · Quantitative Biology 2022-06-23 Cooper J. Mellema , Kevin P. Nguyen , Alex Treacher , Aixa Andrade Hernandez , Albert A. Montillo
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