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Interactive medical consultation requires an agent to proactively elicit missing clinical evidence under uncertainty. Yet existing evaluations largely remain static or outcome-centric, neglecting the evidence-gathering process. In this…

Computation and Language · Computer Science 2026-01-28 Zhuohan Long , Zhijie Bao , Zhongyu Wei

Medication adherence is a well-known problem for pharmaceutical treatment of chronic diseases. Understanding how nonadherence affects treatment efficacy is made difficult by the ethics of clinical trials that force patients to skip doses of…

Quantitative Methods · Quantitative Biology 2021-12-30 Elijah D Counterman , Sean D Lawley

Recent progress in Medical Artificial Intelligence (AI) has delivered systems that can reach clinical expert level performance. However, such systems tend to demonstrate sub-optimal "out-of-distribution" performance when evaluated in…

The advent of Large Language Models (LLMs) offers potential solutions to address problems such as shortage of medical resources and low diagnostic consistency in psychiatric clinical practice. Despite this potential, a robust and…

Computation and Language · Computer Science 2025-06-19 Shuyu Liu , Ruoxi Wang , Ling Zhang , Xuequan Zhu , Rui Yang , Xinzhu Zhou , Fei Wu , Zhi Yang , Cheng Jin , Gang Wang

Clinical decision-making is a feedback system where risk estimates influence treatment, which in turn changes disease trajectories, and both shape clinicians' measurement practices. Static prediction often fails clinically: models trained…

Artificial Intelligence · Computer Science 2026-05-19 Pujun Feng , Xiaoyu Guo , Seyed Ehsan Saffari , Min Hun Lee , Siew-Kei Lam , Erik Cambria , Xibin Sun , Yangtao Zhou , Tong Yang , Xiaoyu Zhang , Tao Tan , Yue Sun , Bin Cui

AUCMEDI is a Python-based framework for medical image classification. In this paper, we evaluate the capabilities of AUCMEDI, by applying it to multiple datasets. Datasets were specifically chosen to cover a variety of medical disciplines…

Image and Video Processing · Electrical Eng. & Systems 2022-10-21 Simone Mayer , Dominik Müller , Frank Kramer

Large Language Models (LLMs) are increasingly being explored for clinical question answering and decision support, yet safe deployment critically requires reliable handling of patient measurements in heterogeneous clinical notes. Existing…

Computation and Language · Computer Science 2026-04-16 Minh-Vuong Nguyen , Fatemeh Shiri , Zhuang Li , Karin Verspoor

Continuing advances in Large Language Models (LLMs) in artificial intelligence offer important capacities in intuitively accessing and using medical knowledge in many contexts, including education and training as well as assessment and…

Computation and Language · Computer Science 2024-08-01 Roma Shusterman , Allison C. Waters , Shannon O`Neill , Phan Luu , Don M. Tucker

Evaluating large language models (LLMs) has recently emerged as a critical issue for safe and trustworthy application of LLMs in the medical domain. Although a variety of static medical question-answering (QA) benchmarks have been proposed,…

Computation and Language · Computer Science 2025-12-12 Gyutaek Oh , Sangjoon Park , Byung-Hoon Kim

Combinatorial medication recommendation(CMR) is a fundamental task of healthcare, which offers opportunities for clinical physicians to provide more precise prescriptions for patients with intricate health conditions, particularly in the…

Artificial Intelligence · Computer Science 2025-01-14 Jie Tan , Yu Rong , Kangfei Zhao , Tian Bian , Tingyang Xu , Junzhou Huang , Hong Cheng , Helen Meng

Large language models (LLMs) are increasingly envisioned as decision-support tools in clinical practice, yet safe clinical reasoning demands integrating heterogeneous knowledge bases -- trials, primary studies, regulatory documents, and…

Computation and Language · Computer Science 2025-05-22 Shan Chen , Pedro Moreira , Yuxin Xiao , Sam Schmidgall , Jeremy Warner , Hugo Aerts , Thomas Hartvigsen , Jack Gallifant , Danielle S. Bitterman

Makeup plays a vital role in self-expression, identity, and confidence - yet remains an underexplored domain for assistive technology, especially for people with vision impairments. While existing tools support isolated tasks such as color…

Human-Computer Interaction · Computer Science 2025-07-08 Franklin Mingzhe Li , Akihiko Oharazawa , Chloe Qingyu Zhu , Misty Fan , Daisuke Sato , Chieko Asakawa , Patrick Carrington

Timely transition from intravenous (IV) to oral antibiotic therapy shortens hospital stays, reduces catheter-related infections, and lowers healthcare costs, yet one in five patients in England remain on IV antibiotics despite meeting…

Machine Learning · Computer Science 2026-03-10 Magnus Ross , Nel Swanepoel , Akish Luintel , Emma McGuire , Ingemar J. Cox , Steve Harris , Vasileios Lampos

Background: Artificial Intelligence (AI) clinical decision support (CDS) systems have the potential to augment surgical risk assessments, but successful adoption depends on an understanding of end-user needs and current workflows. This…

Human-Computer Interaction · Computer Science 2025-04-04 Andrea E Davidson , Jessica M Ray , Yulia Levites Strekalova , Parisa Rashidi , Azra Bihorac

Large language models(LLMs) increasingly match expert performance on licensing examinations, yet routine clinical use remains limited because governance requires auditable reasoning, safety and ethics alignment, and resilience to…

Multimodal data modeling has emerged as a powerful approach in clinical research, enabling the integration of diverse data types such as imaging, genomics, wearable sensors, and electronic health records. Despite its potential to improve…

Objective: Retrieval-based Clinical Decision Support (ReCDS) can aid clinical workflow by providing relevant literature and similar patients for a given patient. However, the development of ReCDS systems has been severely obstructed by the…

Computation and Language · Computer Science 2023-12-21 Zhengyun Zhao , Qiao Jin , Fangyuan Chen , Tuorui Peng , Sheng Yu

In drug discovery, predicting the absorption, distribution, metabolism, excretion, and toxicity (ADMET) properties of small-molecule drugs is critical for ensuring safety and efficacy. However, the process of accurately predicting these…

Machine Learning · Computer Science 2026-03-27 Bohao Xu , Yingzhou Lu , Chenhao Li , Ling Yue , Xiao Wang , Tianfan Fu , Minjie Shen , Lulu Chen

Objective: Create precise, structured, data-backed guidelines for type 2 diabetes treatment progression, suitable for clinical adoption. Research Design and Methods: Our training cohort was composed of patient (with type 2 diabetes) visits…

Artificial Intelligence · Computer Science 2025-04-18 Dewang Kumar Agarwal , Dimitris J. Bertsimas

Artificial intelligence (AI) holds great promise for supporting clinical trials, from patient recruitment and endpoint assessment to treatment response prediction. However, deploying AI without safeguards poses significant risks,…

Machine Learning · Computer Science 2025-10-09 Yao Chen , David Ohlssen , Aimee Readie , Gregory Ligozio , Ruvie Martin , Thibaud Coroller