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Background: Polypharmacy, i.e. taking five drugs or more, is both a public health and an economic issue. Medication reviews are structured interviews of the patient by the community pharmacist, aiming at optimizing the drug treatment and…

A comprehensive pharmaceutical recommendation system was designed based on the patients and drugs features extracted from Drugs.com and Druglib.com. First, data from these databases were combined, and a dataset of patients and drug…

Biomedical data is inherently multimodal, consisting of electronic health records, medical imaging, digital pathology, genome sequencing, wearable sensors, and more. The application of artificial intelligence tools to these multifaceted…

Machine Learning · Computer Science 2024-08-26 Shentong Mo , Paul Pu Liang

Medication recommendation using Electronic Health Records (EHR) is challenging due to complex medical data. Current approaches extract longitudinal information from patient EHR to personalize recommendations. However, existing models often…

Machine Learning · Computer Science 2023-09-27 Jiacong Mi , Yi Zu , Zhuoyuan Wang , Jieyue He

Background and Objective High medicine diversity has always been a significant challenge for prescription, causing confusion or doubt in physicians' decision-making process. This paper aims to develop a medicine recommender system called…

Information Retrieval · Computer Science 2022-06-10 Maryam Sajde , Hamed Malek , Mehran Mohsenzadeh

Numerous medical systems powered by Large Language Models (LLMs) have achieved remarkable progress in diverse healthcare tasks. However, research on their medication safety remains limited due to the lack of real world datasets, constrained…

Artificial Intelligence · Computer Science 2025-11-07 Jiahao Zhao , Luxin Xu , Minghuan Tan , Lichao Zhang , Ahmadreza Argha , Hamid Alinejad-Rokny , Min Yang

AI based mental health diagnosis is often judged by benchmark accuracy, yet in practice its value depends on how psychologists respond whether they accept, adjust, or reject AI suggestions. Mental health makes this especially challenging:…

Human-Computer Interaction · Computer Science 2025-12-11 Filippo Cenacchi , Longbing Cao , Deborah Richards

Healthcare professionals need effective ways to use, understand, and validate AI-driven clinical decision support systems. Existing systems face two key limitations: complex visualizations and a lack of grounding in scientific evidence. We…

Human-Computer Interaction · Computer Science 2025-07-08 Reza Samimi , Aditya Bhattacharya , Lucija Gosak , Gregor Stiglic , Katrien Verbert

We introduce MultiMedEval, an open-source toolkit for fair and reproducible evaluation of large, medical vision-language models (VLM). MultiMedEval comprehensively assesses the models' performance on a broad array of six multi-modal tasks,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-19 Corentin Royer , Bjoern Menze , Anjany Sekuboyina

Medication recommendation aims to integrate patients' long-term health records to provide accurate and safe medication combinations for specific health states. Existing methods often fail to deeply explore the true causal relationships…

Information Retrieval · Computer Science 2024-10-31 Shunpan Liang , Xiang Li , Shi Mu , Chen Li , Yu Lei , Yulei Hou , Tengfei Ma

With the growing imbalance between limited medical resources and escalating demands, AI-based clinical tasks have become paramount. As a sub-domain, medication recommendation aims to amalgamate longitudinal patient history with medical…

Artificial Intelligence · Computer Science 2023-11-28 Xiang Li , Shunpan Liang , Yulei Hou , Tengfei Ma

Depression is a widespread mental disorder that affects millions worldwide. While automated depression assessment shows promise, most studies rely on limited or non-clinically validated data, and often prioritize complex model design over…

Computation and Language · Computer Science 2025-08-07 Zhuang Chen , Guanqun Bi , Wen Zhang , Jiawei Hu , Aoyun Wang , Xiyao Xiao , Kun Feng , Minlie Huang

Background: Simulated patient systems are important in medical education and research, providing safe, integrative training environments and supporting clinical decision making. Advances in artificial intelligence (AI), especially large…

Dermatological care via telemedicine often lacks the rich context of in-person visits. Clinicians must make diagnoses based on a handful of images and brief descriptions, without the benefit of physical exams, second opinions, or reference…

Artificial Intelligence · Computer Science 2025-08-27 Karishma Thakrar , Shreyas Basavatia , Akshay Daftardar

Interprofessional education has long relied on case studies and the use of standardized patients to support teamwork, communication, and related collaborative competencies among healthcare professionals. However, traditional approaches are…

Emerging Technologies · Computer Science 2026-02-13 Ruijie Wang , Jie Lu , Bo Pei , Evonne Jones , Jamey Brinson , Timothy Brown

Reasoning Large Language Models (LLMs) with enhanced accuracy and explainability are increasingly being adopted in the medical domain, as the life-critical nature of clinical decision-making demands reliable support. Despite these…

Computation and Language · Computer Science 2025-11-12 Sung-Min Lee , Siyoon Lee , Juyeon Kim , Kyoungmin Roh

Clinical decision support systems are software tools that help clinicians to make medical decisions. However, their acceptance by clinicians is usually rather low. A known problem is that they often require clinicians to manually enter lots…

Artificial Intelligence · Computer Science 2023-09-20 Jean-Baptiste Lamy , Abdelmalek Mouazer , Karima Sedki , Sophie Dubois , Hector Falcoff

Medication recommendations aim to generate safe and effective medication sets from health records. However, accurately recommending medications hinges on inferring a patient's latent clinical condition from sparse and noisy observations,…

Information Retrieval · Computer Science 2026-03-20 Xiangxu Zhang , Xiao Zhou , Hongteng Xu , Jianxun Lian

There is growing interest in using machine learning (ML) to support clinical diagnosis, but most approaches rely on static, fully observed datasets and fail to reflect the sequential, resource-aware reasoning clinicians use in practice.…

Artificial Intelligence · Computer Science 2025-11-18 Silas Ruhrberg Estévez , Nicolás Astorga , Mihaela van der Schaar

Background: In medical and health professions education (HPE), AI is increasingly used to assess clinical competencies, including via virtual standardized patients. However, most evaluations rely on AI-human interrater reliability and lack…

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