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Vision impairment and blindness are a major global health challenge where gaps in the ophthalmology workforce limit access to specialist care. We evaluate AMIE, a medically fine-tuned conversational system based on Gemini with integrated…

The deployment of Large Language Models (LLMs) in high-stakes clinical settings demands rigorous and reliable evaluation. However, existing medical benchmarks remain static, suffering from two critical limitations: (1) data contamination,…

Artificial Intelligence · Computer Science 2026-02-12 Zhiling Yan , Dingjie Song , Zhe Fang , Yisheng Ji , Xiang Li , Quanzheng Li , Lichao Sun

A patient undergoes multiple examinations in each hospital stay, where each provides different facets of the health status. These assessments include temporal data with varying sampling rates, discrete single-point measurements, therapeutic…

Computer Vision and Pattern Recognition · Computer Science 2025-01-31 Malte Tölle , Mohamad Scharaf , Samantha Fischer , Christoph Reich , Silav Zeid , Christoph Dieterich , Benjamin Meder , Norbert Frey , Philipp Wild , Sandy Engelhardt

There has been much progress in data-driven artificial intelligence technology for medical image analysis in the last decades. However, it still remains challenging due to its distinctive complexity of acquiring and annotating image data,…

Computer Vision and Pattern Recognition · Computer Science 2021-06-30 Chao Gou , Tianyu Shen , Wenbo Zheng , Huadan Xue , Hui Yu , Qiang Ji , Zhengyu Jin , Fei-Yue Wang

We selected 29 medical imaging projects from 48 candidates, assessed 10 software qualities by answering 108 questions for each software project, and interviewed 8 of the 29 development teams. Based on the quantitative data, we ranked the MI…

Software Engineering · Computer Science 2024-05-21 W. Spencer Smith , Ao Dong , Jacques Carette , Michael D. Noseworthy

Evaluating large language models (LLMs) in medicine is crucial because medical applications require high accuracy with little room for error. Current medical benchmarks have three main types: medical exam-based, comprehensive medical, and…

Medication recommendation is crucial in healthcare, offering effective treatments based on patient's electronic health records (EHR). Previous studies show that integrating more medication-related knowledge improves medication…

Artificial Intelligence · Computer Science 2025-04-28 Xiang Li , Haixu Ma , Guanyong Wu , Shi Mu , Chen Li , Shunpan Liang

Existing works based on molecular knowledge neglect the 3D geometric structure of molecules and fail to learn the high-dimensional information of medications, leading to structural confusion. Additionally, it does not extract key…

Machine Learning · Computer Science 2024-11-13 Shi Mu , Chen Li , Xiang Li , Shunpan Liang

Network meta-analysis is a powerful tool to synthesize evidence from independent studies and compare multiple treatments simultaneously. A critical task of performing a network meta-analysis is to offer ranks of all available treatment…

Methodology · Statistics 2022-07-15 Andrés F. Barrientos , Garritt L. Page , Lifeng Lin

Recent advancements in medical entity linking have been applied in the area of scientific literature and social media data. However, with the adoption of telemedicine and conversational agents such as Alexa in healthcare settings, medical…

Computation and Language · Computer Science 2020-10-13 Shaoqing Yuan , Parminder Bhatia , Busra Celikkaya , Haiyang Liu , Kyunghwan Choi

The objective of this work was to assess the clinical performance of an unsupervised machine learning model aimed at identifying unusual medication orders and pharmacological profiles. We conducted a prospective study between April 2020 and…

Importance: We introduce a novel Retrieval Augmented Generation (RAG)-Large Language Model (LLM) framework as a Clinical Decision Support Systems (CDSS) to support safe medication prescription. Objective: To evaluate the efficacy of…

Medication recommendation systems have gained significant attention in healthcare as a means of providing tailored and effective drug combinations based on patients' clinical information. However, existing approaches often suffer from…

Machine Learning · Computer Science 2024-08-13 Zihao Zhao , Yi Jing , Fuli Feng , Jiancan Wu , Chongming Gao , Xiangnan He

PubMed is a freely accessible system for searching the biomedical literature, with approximately 2.5 million users worldwide on an average workday. We have recently developed PubMed Labs (www.pubmed.gov/labs), an experimental platform for…

Millions of individuals' well-being are challenged by the harms of substance use. Harm reduction as a public health strategy is designed to improve their health outcomes and reduce safety risks. Some large language models (LLMs) have…

Computation and Language · Computer Science 2025-07-30 Kaixuan Wang , Chenxin Diao , Jason T. Jacques , Zhongliang Guo , Shuai Zhao

Medication recommendation is a crucial task for intelligent healthcare systems. Previous studies mainly recommend medications with electronic health records (EHRs). However, some details of interactions between doctors and patients may be…

Computation and Language · Computer Science 2022-09-16 Zhenfeng He , Yuqiang Han , Zhenqiu Ouyang , Wei Gao , Hongxu Chen , Guandong Xu , Jian Wu

The application of the Multi-modal Large Language Models (MLLMs) in medical clinical scenarios remains underexplored. Previous benchmarks only focus on the capacity of the MLLMs in medical visual question-answering (VQA) or report…

Computation and Language · Computer Science 2024-08-19 Hongcheng Liu , Yusheng Liao , Siqv Ou , Yuhao Wang , Heyang Liu , Yanfeng Wang , Yu Wang

With the recent advances in A.I. methodologies and their application to medical imaging, there has been an explosion of related research programs utilizing these techniques to produce state-of-the-art classification performance. Ultimately,…

In November 27, 2018, Amazon Web Services (AWS) released Amazon Comprehend Medical (ACM), a deep learning based system that automatically extracts clinical concepts (which include anatomy, medical conditions, protected health information…

Computation and Language · Computer Science 2020-02-04 Benedict Guzman , MS , Isabel Metzger , MS , Yindalon Aphinyanaphongs , M. D. , Ph. D. , Himanshu Grover , Ph. D

The process of electronic approach to writing and sending medical prescription promises to improve patient safety, health outcomes, maintaining patients privacy, promoting clinician acceptance and prescription security when compared with…

Computers and Society · Computer Science 2015-06-12 Adebayo Omotosho , Emuoyibofarhe Justice