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Brain image registration transforms a pair of images into one system with the matched imaging contents, which is of essential importance for brain image analysis. This paper presents a novel framework for unsupervised 3D brain image…

Computer Vision and Pattern Recognition · Computer Science 2019-07-04 Lihao Liu , Xiaowei Hu , Lei Zhu , Pheng-Ann Heng

Registration of brain MRI images requires to solve a deformation field, which is extremely difficult in aligning intricate brain tissues, e.g., subcortical nuclei, etc. Existing efforts resort to decomposing the target deformation field…

Image and Video Processing · Electrical Eng. & Systems 2022-04-27 Jinxin Lv , Zhiwei Wang , Hongkuan Shi , Haobo Zhang , Sheng Wang , Yilang Wang , Qiang Li

In this study, we focus on brain tumor sequence registration between pre-operative and follow-up Magnetic Resonance Imaging (MRI) scans of brain glioma patients, in the context of Brain Tumor Sequence Registration challenge (BraTS-Reg…

Computer Vision and Pattern Recognition · Computer Science 2023-07-18 Mingyuan Meng , Lei Bi , Dagan Feng , Jinman Kim

CT and MRI are two of the most informative modalities in spinal diagnostics and treatment planning. CT is useful when analysing bony structures, while MRI gives information about the soft tissue. Thus, fusing the information of both…

Registration is a fundamental task in medical robotics and is often a crucial step for many downstream tasks such as motion analysis, intra-operative tracking and image segmentation. Popular registration methods such as ANTs and NiftyReg…

Computer Vision and Pattern Recognition · Computer Science 2021-03-26 Wentao Zhu , Yufang Huang , Daguang Xu , Zhen Qian , Wei Fan , Xiaohui Xie

Accelerating MRI scans is one of the principal outstanding problems in the MRI research community. Towards this goal, we hosted the second fastMRI competition targeted towards reconstructing MR images with subsampled k-space data. We…

In this paper, we present our submission to the LUMIR25 task of Learn2Reg 2025, which ranked 1st overall on the test set. Extended from LUMIR24, this year's task focuses on zero-shot registration under domain shifts (e.g., high-field MRI,…

Image and Video Processing · Electrical Eng. & Systems 2026-02-24 Hengjie Liu , Yimeng Dou , Di Xu , Xinyi Fu , Dan Ruan , Ke Sheng

Although developed functional magnetic resonance imaging (fMRI) registration algorithms based on deep learning have achieved a certain degree of alignment of functional area, they underutilized fine structural information. In this paper, we…

Image and Video Processing · Electrical Eng. & Systems 2024-09-27 Baolong Li , Yuhu Shi , Lei Wang , Weiming Zeng , Changming Zhu

We propose a fully unsupervised multi-modal deformable image registration method (UMDIR), which does not require any ground truth deformation fields or any aligned multi-modal image pairs during training. Multi-modal registration is a key…

Computer Vision and Pattern Recognition · Computer Science 2019-03-25 Chen Qin , Bibo Shi , Rui Liao , Tommaso Mansi , Daniel Rueckert , Ali Kamen

Medical image segmentation is a relevant task as it serves as the first step for several diagnosis processes, thus it is indispensable in clinical usage. Whilst major success has been reported using supervised techniques, they assume a…

Computer Vision and Pattern Recognition · Computer Science 2022-07-22 Lihao Liu , Angelica I Aviles-Rivero , Carola-Bibiane Schönlieb

Developing Foundation Models for medical image analysis is essential to overcome the unique challenges of radiological tasks. The first challenges of this kind for 3D brain MRI, SSL3D and FOMO25, were held at MICCAI 2025. Our solution…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Pedro M. Gordaliza , Jaume Banus , Benoît Gérin , Maxence Wynen , Nataliia Molchanova , Jonas Richiardi , Meritxell Bach Cuadra

Tumor segmentation from multi-modal brain MRI images is a challenging task due to the limited samples, high variance in shapes and uneven distribution of tumor morphology. The performance of automated medical image segmentation has been…

Image and Video Processing · Electrical Eng. & Systems 2024-02-13 Tianyi Ren , Ethan Honey , Harshitha Rebala , Abhishek Sharma , Agamdeep Chopra , Mehmet Kurt

Deformable registration of magnetic resonance images between patients with brain tumors and healthy subjects has been an important tool to specify tumor geometry through location alignment and facilitate pathological analysis. Since tumor…

Image and Video Processing · Electrical Eng. & Systems 2021-01-19 Xiaofeng Liu , Fangxu Xing , Chao Yang , C. -C. Jay Kuo , Georges ElFakhri , Jonghye Woo

Registration is a fundamental task in medical image analysis which can be applied to several tasks including image segmentation, intra-operative tracking, multi-modal image alignment, and motion analysis. Popular registration tools such as…

Computer Vision and Pattern Recognition · Computer Science 2019-10-07 Wentao Zhu , Andriy Myronenko , Ziyue Xu , Wenqi Li , Holger Roth , Yufang Huang , Fausto Milletari , Daguang Xu

Deep unsupervised representation learning has recently led to new approaches in the field of Unsupervised Anomaly Detection (UAD) in brain MRI. The main principle behind these works is to learn a model of normal anatomy by learning to…

Image and Video Processing · Electrical Eng. & Systems 2020-04-09 Christoph Baur , Stefan Denner , Benedikt Wiestler , Shadi Albarqouni , Nassir Navab

Classical deformable registration techniques achieve impressive results and offer a rigorous theoretical treatment, but are computationally intensive since they solve an optimization problem for each image pair. Recently, learning-based…

Computer Vision and Pattern Recognition · Computer Science 2019-07-26 Adrian V. Dalca , Guha Balakrishnan , John Guttag , Mert R. Sabuncu

Most of the deep learning based medical image registration algorithms focus on brain image registration tasks.Compared with brain registration, the chest CT registration has larger deformation, more complex background and region over-lap.…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Cheng Wang , Qiyu Gao , Fandong Zhang , Shu Zhang , Yizhou Yu

Cortical surface registration is a fundamental tool for neuroimaging analysis that has been shown to improve the alignment of functional regions relative to volumetric approaches. Classically, image registration is performed by optimizing a…

Computer Vision and Pattern Recognition · Computer Science 2022-03-25 Mohamed A. Suliman , Logan Z. J. Williams , Abdulah Fawaz , Emma C. Robinson

Accurate segmentation of fetal brain magnetic resonance images is crucial for analyzing fetal brain development and detecting potential neurodevelopmental abnormalities. Traditional deep learning-based automatic segmentation, although…

Detecting brain lesions as abnormalities observed in magnetic resonance imaging (MRI) is essential for diagnosis and treatment. In the search of abnormalities, such as tumors and malformations, radiologists may benefit from computer-aided…

Computer Vision and Pattern Recognition · Computer Science 2026-03-27 Hassan Baker , Austin J. Brockmeier