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Deep learning-based models in medical imaging often struggle to generalize effectively to new scans due to data heterogeneity arising from differences in hardware, acquisition parameters, population, and artifacts. This limitation presents…

Image and Video Processing · Electrical Eng. & Systems 2023-08-09 Sebastian Nørgaard Llambias , Mads Nielsen , Mostafa Mehdipour Ghazi

In the field of medical image analysis, image registration is a crucial technique. Despite the numerous registration models that have been proposed, existing methods still fall short in terms of accuracy and interpretability. In this paper,…

Computer Vision and Pattern Recognition · Computer Science 2024-10-25 Jiaofen Nan , Gaodeng Fan , Kaifan Zhang , Chen Zhao , Fubao Zhu , Weihua Zhou

Registration of pre-operative and post-recurrence brain images is often needed to evaluate the effectiveness of brain gliomas treatment. While recent deep learning-based deformable registration methods have achieved remarkable success with…

Image and Video Processing · Electrical Eng. & Systems 2022-06-09 Tony C. W. Mok , Albert C. S. Chung

In clinical practice, well-aligned multi-modal images, such as Magnetic Resonance (MR) and Computed Tomography (CT), together can provide complementary information for image-guided therapies. Multi-modal image registration is essential for…

Computer Vision and Pattern Recognition · Computer Science 2022-04-29 Zekang Chen , Jia Wei , Rui Li

We present a fast learning-based algorithm for deformable, pairwise 3D medical image registration. Current registration methods optimize an objective function independently for each pair of images, which can be time-consuming for large…

Computer Vision and Pattern Recognition · Computer Science 2019-03-14 Guha Balakrishnan , Amy Zhao , Mert R. Sabuncu , John Guttag , Adrian V. Dalca

Unsupervised learning strategy is widely adopted by the deformable registration models due to the lack of ground truth of deformation fields. These models typically depend on the intensity-based similarity loss to obtain the learning…

Image and Video Processing · Electrical Eng. & Systems 2021-12-21 Luyi Han , Haoran Dou , Yunzhi Huang , Pew-Thian Yap

Surgical navigation based on multimodal image registration has played a significant role in providing intraoperative guidance to surgeons by showing the relative position of the target area to critical anatomical structures during surgery.…

Computer Vision and Pattern Recognition · Computer Science 2026-02-17 Jiazheng Wang , Zeyu Liu , Min Liu , Xiang Chen , Xinyao Yu , Yaonan Wang , Hang Zhang

Establishing voxelwise semantic correspondence across distinct imaging modalities is a foundational yet formidable computer vision task. Current multi-modality registration techniques maximize hand-crafted inter-domain similarity functions,…

Computer Vision and Pattern Recognition · Computer Science 2022-06-28 Neel Dey , Jo Schlemper , Seyed Sadegh Mohseni Salehi , Bo Zhou , Guido Gerig , Michal Sofka

The segmentation of lesions in Moderate to Severe Traumatic Brain Injury (msTBI) presents a significant challenge in neuroimaging due to the diverse characteristics of these lesions, which vary in size, shape, and distribution across brain…

Computer Vision and Pattern Recognition · Computer Science 2025-04-10 Constantin Ulrich , Tassilo Wald , Fabian Isensee , Klaus H. Maier-Hein

Intraoperative navigation in spine surgery demands millimeter-level accuracy. Currently, this is achieved through radiation-intensive intraoperative imaging and bone-anchored markers that are invasive and disrupt surgical workflow.…

Computer Vision and Pattern Recognition · Computer Science 2026-05-21 Lorenzo Pettinari , Sidaty El Hadramy , Michael Wehrli , Philippe C. Cattin , Daniel Studer , Carol C. Hasler , Maria Licci

Learning non-rigid registration in an end-to-end manner is challenging due to the inherent high degrees of freedom and the lack of labeled training data. In this paper, we resolve these two challenges simultaneously. First, we propose to…

Computer Vision and Pattern Recognition · Computer Science 2021-04-14 Wanquan Feng , Juyong Zhang , Hongrui Cai , Haofei Xu , Junhui Hou , Hujun Bao

This paper introduces GeoMorph, a novel geometric deep-learning framework designed for image registration of cortical surfaces. The registration process consists of two main steps. First, independent feature extraction is performed on each…

Machine Learning · Computer Science 2023-11-23 Mohamed A. Suliman , Logan Z. J. Williams , Abdulah Fawaz , Emma C. Robinson

Many applications in image-guided surgery and therapy require fast and reliable non-linear, multi-modal image registration. Recently proposed unsupervised deep learning-based registration methods have demonstrated superior performance…

Image and Video Processing · Electrical Eng. & Systems 2022-10-07 Gerard Snaauw , Michele Sasdelli , Gabriel Maicas , Stephan Lau , Johan Verjans , Mark Jenkinson , Gustavo Carneiro

Deep learning techniques have led to state-of-the-art image super resolution with natural images. Normally, pairs of high-resolution and low-resolution images are used to train the deep learning models. These techniques have also been…

Image and Video Processing · Electrical Eng. & Systems 2022-10-14 Yutaro Iwamoto , Kyohei Takeda , Yinhao Li , Akihiko Shiino , Yen-Wei Chen

Semi-supervised learning, which leverages both annotated and unannotated data, is an efficient approach for medical image segmentation, where obtaining annotations for the whole dataset is time-consuming and costly. Traditional…

Computer Vision and Pattern Recognition · Computer Science 2025-02-06 Ruizhe Li , Grazziela Figueredo , Dorothee Auer , Rob Dineen , Paul Morgan , Xin Chen

We present an implementation of a new approach to diffeomorphic non-rigid registration of medical images. The method is based on optical flow and warps images via gradient flow with the standard $L^2$ inner product. To compute the…

Computer Vision and Pattern Recognition · Computer Science 2019-04-25 Daniel Grzech , Loïc le Folgoc , Mattias P. Heinrich , Bishesh Khanal , Jakub Moll , Julia A. Schnabel , Ben Glocker , Bernhard Kainz

Traditional deformable registration techniques achieve impressive results and offer a rigorous theoretical treatment, but are computationally intensive since they solve an optimization problem for each image pair. Recently, learning-based…

Computer Vision and Pattern Recognition · Computer Science 2019-03-15 Adrian V. Dalca , Guha Balakrishnan , John Guttag , Mert R. Sabuncu

Image registration is a crucial task in signal processing, but it often encounters issues with stability and efficiency. Non-learning registration approaches rely on optimizing similarity metrics between fixed and moving images, which can…

Computer Vision and Pattern Recognition · Computer Science 2023-03-28 Zihao Wang , Hervé Delingette

Multi-contrast magnetic resonance (MR) image registration is useful in the clinic to achieve fast and accurate imaging-based disease diagnosis and treatment planning. Nevertheless, the efficiency and performance of the existing registration…

Image and Video Processing · Electrical Eng. & Systems 2021-02-17 Weijian Huang , Hao Yang , Xinfeng Liu , Cheng Li , Ian Zhang , Rongpin Wang , Hairong Zheng , Shanshan Wang

Deformable medical image registration is an essential task in computer-assisted interventions. This problem is particularly relevant to oncological treatments, where precise image alignment is necessary for tracking tumor growth, assessing…

Computer Vision and Pattern Recognition · Computer Science 2025-06-04 Stefano Fogarollo , Gregor Laimer , Reto Bale , Matthias Harders