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Brain extraction and registration are important preprocessing steps in neuroimaging data analysis, where the goal is to extract the brain regions from MRI scans (i.e., extraction step) and align them with a target brain image (i.e.,…

Computer Vision and Pattern Recognition · Computer Science 2022-12-08 Yao Su , Zhentian Qian , Lifang He , Xiangnan Kong

In clinical practice, imaging modalities with functional characteristics, such as positron emission tomography (PET) and fractional anisotropy (FA), are often aligned with a structural reference (e.g., MRI, CT) for accurate interpretation…

Computer Vision and Pattern Recognition · Computer Science 2025-07-01 Kyobin Choo , Hyunkyung Han , Jinyeong Kim , Chanyong Yoon , Seong Jae Hwang

We introduce "PatchMorph," an new stochastic deep learning algorithm tailored for unsupervised 3D brain image registration. Unlike other methods, our method uses compact patches of a constant small size to derive solutions that can combine…

Computer Vision and Pattern Recognition · Computer Science 2024-10-28 Henrik Skibbe , Michal Byra , Akiya Watakabe , Tetsuo Yamamori , Marco Reisert

In this paper, we propose a novel unsupervised learning method to learn the brain dynamics using a deep learning architecture named residual D-net. As it is often the case in medical research, in contrast to typical deep learning tasks, the…

Machine Learning · Statistics 2019-03-01 Youngjoo Seo , Manuel Morante , Yannis Kopsinis , Sergios Theodoridis

Purpose: This study aims to explore training strategies to improve convolutional neural network-based image-to-image deformable registration for abdominal imaging. Methods: Different training strategies, loss functions, and transfer…

Image and Video Processing · Electrical Eng. & Systems 2023-02-28 Javier Pérez de Frutos , André Pedersen , Egidijus Pelanis , David Bouget , Shanmugapriya Survarachakan , Thomas Langø , Ole-Jakob Elle , Frank Lindseth

We introduce a strategy for learning image registration without acquired imaging data, producing powerful networks agnostic to contrast introduced by magnetic resonance imaging (MRI). While classical registration methods accurately estimate…

Image and Video Processing · Electrical Eng. & Systems 2022-03-04 Malte Hoffmann , Benjamin Billot , Douglas N. Greve , Juan Eugenio Iglesias , Bruce Fischl , Adrian V. Dalca

Current deep learning approaches in medical image registration usually face the challenges of distribution shift and data collection, hindering real-world deployment. In contrast, universal medical image registration aims to perform…

Computer Vision and Pattern Recognition · Computer Science 2024-06-26 Bomin Wang , Xinzhe Luo , Xiahai Zhuang

We present two practical improvement techniques for unsupervised segmentation learning. These techniques address limitations in the resolution and accuracy of predicted segmentation maps of recent state-of-the-art methods. Firstly, we…

Computer Vision and Pattern Recognition · Computer Science 2024-12-02 Alp Eren Sari , Francesco Locatello , Paolo Favaro

Unsupervised pre-training has been proven as an effective approach to boost various downstream tasks given limited labeled data. Among various methods, contrastive learning learns a discriminative representation by constructing positive and…

Image and Video Processing · Electrical Eng. & Systems 2022-02-17 Jizong Peng , Ping Wang , Marco Pedersoli , Christian Desrosiers

Multimodal image registration is a challenging but essential step for numerous image-guided procedures. Most registration algorithms rely on the computation of complex, frequently non-differentiable similarity metrics to deal with the…

Computer Vision and Pattern Recognition · Computer Science 2023-07-20 Matteo Ronchetti , Wolfgang Wein , Nassir Navab , Oliver Zettinig , Raphael Prevost

Multimodal groupwise registration aligns internal structures in a group of medical images. Current approaches to this problem involve developing similarity measures over the joint intensity profile of all images, which may be…

Computer Vision and Pattern Recognition · Computer Science 2022-12-13 Xin Wang , Xinzhe Luo , Xiahai Zhuang

We present KeyMorph, a deep learning-based image registration framework that relies on automatically detecting corresponding keypoints. State-of-the-art deep learning methods for registration often are not robust to large misalignments, are…

Computer Vision and Pattern Recognition · Computer Science 2023-09-04 Alan Q. Wang , Evan M. Yu , Adrian V. Dalca , Mert R. Sabuncu

Automatic segmentation of brain tumors in intra-operative ultrasound (iUS) images could facilitate localization of tumor tissue during resection surgery. The lack of large annotated datasets limits the current models performances. In this…

Image and Video Processing · Electrical Eng. & Systems 2025-08-18 Mathilde Faanes , Ragnhild Holden Helland , Ole Solheim , Sébastien Muller , Ingerid Reinertsen

The alignment of serial-section electron microscopy (ssEM) images is critical for efforts in neuroscience that seek to reconstruct neuronal circuits. However, each ssEM plane contains densely packed structures that vary from one section to…

Computer Vision and Pattern Recognition · Computer Science 2017-12-06 Inwan Yoo , David G. C. Hildebrand , Willie F. Tobin , Wei-Chung Allen Lee , Won-Ki Jeong

We propose a unified deep meta-learning framework for accelerated magnetic resonance imaging (MRI) that jointly addresses multi-coil reconstruction and cross-modality synthesis. Motivated by the limitations of conventional methods in…

Optimization and Control · Mathematics 2026-03-10 Merham Fouladvand , Peuroly Batra

Longitudinal image registration enables studying temporal changes in brain morphology which is useful in applications where monitoring the growth or atrophy of specific structures is important. However this task is challenging due to;…

Computer Vision and Pattern Recognition · Computer Science 2025-04-15 Aisha L. Shuaibu , Kieran A. Gibb , Peter A. Wijeratne , Ivor J. A. Simpson

Retrospective analysis of brain MRI scans acquired in the clinic has the potential to enable neuroimaging studies with sample sizes much larger than those found in research datasets. However, analysing such clinical images "in the wild" is…

Image and Video Processing · Electrical Eng. & Systems 2023-01-06 Benjamin Billot , Magdamo Colin , Sean E. Arnold , Sudeshna Das , Juan. E. Iglesias

We introduce SparseVM, a method that registers clinical-quality 3D MR scans both faster and more accurately than previously possible. Deformable alignment, or registration, of clinical scans is a fundamental task for many clinical…

Computer Vision and Pattern Recognition · Computer Science 2020-04-07 Kathleen M. Lewis , Natalia S. Rost , John Guttag , Adrian V. Dalca

Neuroanatomical segmentation in magnetic resonance imaging (MRI) of the brain is a prerequisite for volume, thickness and shape measurements. This work introduces a new highly accurate and versatile method based on 3D convolutional neural…

Quantitative Methods · Quantitative Biology 2019-02-07 Philip Novosad , Vladimir Fonov , D. Louis Collins
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