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Collective cell migration in epithelia relies on cell intercalation: a local remodelling of the cellular network that allows neighbouring cells to swap their positions. Unlike foams and passive cellular fluid, in epithelial intercalation…

Soft Condensed Matter · Physics 2025-10-31 Dimitrios Krommydas , Livio Nicola Carenza , Luca Giomi

We study how confinement transforms the chaotic dynamics of bulk microtubule-based active nematics into regular spatiotemporal patterns. For weak confinements, multiple continuously nucleating and annihilating topological defects…

Polar active matter - including animal herds, aggregates of motile cells and active colloids - often forms coordinated migration patterns, such as flocking. This orderly motion can be disrupted by full-integer topological defects…

Soft Condensed Matter · Physics 2026-05-26 Luiza Angheluta , Anna Lång , Emma Lång , Stig Ove Bøe

The problem of low Reynolds number turbulence in active nematic fluids is theoretically addressed. Using numerical simulations I demonstrate that an incompressible turbulent flow, in two-dimensional active nematics, consists of an ensemble…

Soft Condensed Matter · Physics 2015-08-04 Luca Giomi

We study the spatiotemporal patterns that emerge when an active nematic film is topologically constraint. These topological constraints allow to control the non-equilibrium dynamics of the active system. We consider ellipsoidal shapes for…

Soft Condensed Matter · Physics 2017-03-13 Francesco Alaimo , Christian Köhler , Axel Voigt

Different cell types aggregate and sort into hierarchical architectures during the formation of animal tissues. The resulting spatial organization depends (in part) on the strength of adhesion of one cell type to itself relative to other…

Quantitative Methods · Quantitative Biology 2023-08-02 Dhananjay Bhaskar , William Y. Zhang , Alexandria Volkening , Björn Sandstede , Ian Y. Wong

By modifying and calibrating an active vertex model to experiments, we have simulated numerically a confluent cellular monolayer spreading on an empty space and the collision of two monolayers of different cells in an antagonistic migration…

Soft Condensed Matter · Physics 2021-04-02 L. L. Bonilla , A. Carpio , C. Trenado

Stable array of point defects was generated in nematic liquid crystal. Point defects with topological charge of +1 and -1 (hedgehogs) were generated in vertically aligned liquid crystal cell. The hedgehogs were arranged in square or…

Soft Condensed Matter · Physics 2019-06-18 Jieh-Wen Tsung

A nematic membrane is a sheet with embedded orientational order, which can occur in biological cells, liquid crystal films, manufactured materials, and other soft matter systems. By formulating the free energy of nematic films using tensor…

Soft Condensed Matter · Physics 2009-11-13 John R. Frank , Mehran Kardar

From incompressible flows to electrostatics, harmonic functions can provide solutions to many two-dimensional problems and, similarly, the director field of a planar nematic can be determined using complex analysis. We derive a closed-form…

Soft Condensed Matter · Physics 2024-12-03 Simon Čopar , Žiga Kos

We investigate similarities in the micro-structural dynamics between externally driven and actively driven nematics. Walls, lines of strong deformations in the director field, and topological defects are characteristic features of an active…

Soft Condensed Matter · Physics 2015-04-28 Sumesh P. Thampi , Ramin Golestanian , Julia M. Yeomans

Control of cell proliferation is a fundamental aspect of tissue physiology central to morphogenesis, wound healing and cancer. Although many of the molecular genetic factors are now known, the system level regulation of growth is still…

Tissues and Organs · Quantitative Biology 2015-06-03 Alberto Puliafito , Lars Hufnagel , Pierre Neveu , Sebastian Streichan , Alex Sigal , Deborah K. Fygenson , Boris I. Shraiman

We analyze the phase behavior of lyotropic nematic liquid crystals in the self-organizing flow, viz. so called active nematics (AN). Their elastic properties are mutually caused by evolution of topological defects (for instance,…

Soft Condensed Matter · Physics 2018-02-20 L. V. Elnikova

With exquisite precision and reproducibility, cells orchestrate the cooperative action of thousands of nanometer-sized molecular motors to carry out mechanical tasks at much larger length scales, such as cell motility, division and…

Soft Condensed Matter · Physics 2013-01-08 Tim Sanchez , Daniel T. N. Chen , Stephen J. DeCamp , Michael Heymann , Zvonimir Dogic

As a method for controlling active materials, researchers have suggested designing patterns of activity on a substrate, which should guide the motion of topological defects. To investigate this concept, we model the behavior of a single…

Soft Condensed Matter · Physics 2021-02-10 Xingzhou Tang , Jonathan V. Selinger

The shapes of epithelial tissues result from a complex interplay of contractile forces in the cytoskeleta of the cells in the tissue, and adhesion forces between them. A host of discrete, cell-based models describe these forces by assigning…

Soft Condensed Matter · Physics 2019-02-27 Pierra A. Haas , Raymond E. Goldstein

It is shown that in deep inelastic electron - ion collisions the detection, in coincidence with the scattered electron, of a nucleus A-1 in the ground state, as well as a nucleon and a nucleus A-2 also in the ground state, may provide…

Nuclear Theory · Physics 2007-05-23 C. Ciofi degli Atti , L. P. Kaptari , S. Scopetta

Colonies of rod-shaped bacteria constitute a system of colloidal active matter with nematic properties. As a single initial bacterium multiplies through repeated divisions, the resulting colony quickly loses long-range orientational order,…

Charge profiles in liquid electrolytes are of crucial importance for applications, such as supercapacitors, fuel cells, batteries, or the self-assembly of particles in colloidal or biological settings. However, creating localised (screened)…

Soft Condensed Matter · Physics 2021-03-17 Jeffrey C. Everts , Miha Ravnik

Studies of how protein fold have shown that the way protein clumps form in the test tube is similar to how proteins form the so-called ``amyloid'' deposits that are the pathological signal of a variety of diseases, among them the memory…

Condensed Matter · Physics 2009-10-31 R. A. Broglia , G. Tiana , S. Pasquali , H. E. Roman , E. Vigezzi