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Collective cell migration is crucial in many biological processes such as wound healing, tissue morphogenesis, and tumor progression. The leading front of a collective migrating epithelial cell layer often destabilizes into multicellular…

Biological Physics · Physics 2020-05-07 Yanjun Yang , Herbert Levine

We investigated the nematic ordering on a torus by means of analytic method and the method of simulated annealing, the Frank free energy, both in the standard form and covariant form, were used in the study. The defect free state was found…

Soft Condensed Matter · Physics 2014-02-25 Han Miao , Yao Li , Hongru Ma

Topological defects are a conspicuous feature of active liquid crystals that have been associated with important morphogenetic transitions in organismal development. Robust development thus requires a tight control of the motion and…

Two-dimensional nematics possess peculiar properties that have been studied recently using computer simulation and various theoretical models. Here we review our own contribution to the field using density-functional theory, and present…

Soft Condensed Matter · Physics 2013-10-07 Daniel de las Heras , Yuri Martinez-Raton , Luis Mederos , Enrique Velasco

The study of topology in solids is undergoing a renaissance following renewed interest in the properties of ferroic domain walls as well as recent discoveries regarding topological insulators and skyrmionic lattices. Each of these systems…

Materials Science · Physics 2021-03-09 Sinead M. Griffin , Nicola A. Spaldin

The incompatibility of linearized piecewise smooth strain field, arising out of volumetric and surface densities of topological defects and metric anomalies, is investigated. First, general forms of compatibility equations are derived for a…

Mathematical Physics · Physics 2019-03-27 Animesh Pandey , Anurag Gupta

Traditional top-down robotic design often lacks the adaptability needed to handle real-world complexities, prompting the need for more flexible approaches. Therefore, this study introduces a novel cellular plasticity model tailored for…

Robotics · Computer Science 2024-08-13 Trevor R. Smith , Thomas J. Smith , Nicholas S. Szczecinski , Sergiy Yakovenko , Yu Gu

We study the dynamics of proliferating cell collectives whose microscopic constituents' growth is inhibited by macroscopic growth-induced stress. Discrete particle simulations of a growing collective show the emergence of concentric-ring…

Biological Physics · Physics 2024-05-17 Scott Weady , Bryce Palmer , Adam Lamson , Taeyoon Kim , Reza Farhadifar , Michael J. Shelley

The language and methods of algebraic topology, particularly homotopy theory, have been extensively used in the study of the identification, the classification and the evolution of defects. Topological methods provide the means for the…

High Energy Physics - Phenomenology · Physics 2007-05-23 E. D. M. Kavoussanaki

Active materials are those in which individual, uncoordinated local stresses drive the material out of equilibrium on a global scale. Examples of such assemblies can be seen across scales from schools of fish to the cellular cytoskeleton…

Soft Condensed Matter · Physics 2022-09-30 Nitin Kumar , Rui Zhang , Steven A. Redford , Juan J. de Pablo , Margaret L. Gardel

Shape transformations of epithelial tissues in three dimensions, which are crucial for embryonic development or in vitro organoid growth, can result from active forces generated within the cytoskeleton of the epithelial cells. How the…

Biological Physics · Physics 2024-12-23 Diana Khoromskaia , Guillaume Salbreux

The study of organoids, artificially grown cell aggregates with the functionality and small-scale anatomy of real organs, is one of the most active areas of research in biology and biophysics, yet the basic physical origins of their…

Biological Physics · Physics 2021-10-12 Jan Rozman , Matej Krajnc , Primož Ziherl

In this paper and a companion one, we study the effect of integrable line defects on entanglement entropy in massive integrable field theories in 1+1 dimensions. The current paper focuses on topological defects that are purely transmissive.…

High Energy Physics - Theory · Physics 2017-09-13 Yunfeng Jiang

This paper is dedicated to studying various aspects of topological defects, appearing in mean-field theory treatments of physical systems such as ultracold atomic gases and gauge field theories. We start by investigating topological charge…

Quantum Gases · Physics 2021-09-14 Toni Annala , Mikko Möttönen

Topological defects are one of the most conspicuous features of liquid crystals. In two dimensional nematics, they have been shown to behave effectively as particles with both, charge and orientation, which dictate their interactions. Here,…

Soft Condensed Matter · Physics 2021-07-14 Daniel J. G. Pearce , Karsten Kruse

Surface growth is a crucial component of many natural and artificial processes from cell proliferation to additive manufacturing. In elastic systems surface growth is usually accompanied by the development of geometrical incompatibility…

Soft Condensed Matter · Physics 2019-05-08 Lev Truskinovsky , Giuseppe Zurlo

Using Monte Carlo simulations of the Lebwohl--Lasher model we study the director ordering in a nematic cell where the top and bottom surfaces are patterned with a lattice of $\pm 1$ point topological defects of lattice spacing $a$. We find…

Soft Condensed Matter · Physics 2009-11-13 Adam S. Backer , A. C. Callan-Jones , Robert A. Pelcovits

We use density--functional theory to study the structure of two-dimensional defects inside a circular nematic nanocavity. The density, nematic order parameter, and director fields, as well as the defect core energy and core radius, are…

Soft Condensed Matter · Physics 2010-12-17 D. de las Heras , L. Mederos , E. Velasco

We present a framework to take new measurements in nematic systems that contain active elements such as molecular motors. Spatio-temporal fields of stress, traction, velocity, pressure, and forces are estimated jointly from microscopy…

Soft Condensed Matter · Physics 2024-12-02 Aleix Boquet-Pujadas , Jérôme Hardouïn , Junhao Wen , Jordi Ignés-Mullol , Francesc Sagués

The two pillars of Algebraic topology - Homology and homotopy theory rely on the availability of basic building blocks called cells. Cells take the form of simplexes, and have properties such as faces, sub-cells, convexity and…

Category Theory · Mathematics 2026-05-12 Suddhasattwa Das