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Cellular processes do not follow deterministic rules; even in identical environments genetically identical cells can make random choices leading to different phenotypes. This randomness originates from fluctuations present in the…

Molecular Networks · Quantitative Biology 2016-02-02 Elijah Roberts , Shay Be'er , Chris Bohrer , Rati Sharma , Michael Assaf

Traditionally, it is understood that fluctuations in the equilibrium distribution are not evident in thermodynamic systems of large $N$ (the number of particles in the system) \cite{Huang1}. In this paper we examine the validity of this…

Mathematical Physics · Physics 2007-10-03 Kieran Kelly , Przemysław Repetowicz , Seosamh macRéamoinn

The phenomena of stochasticity in biochemical processes have been intriguing life scientists for the past few decades. We now know that living cells take advantage of stochasticity in some cases and counteract stochastic effects in others.…

Quantitative Methods · Quantitative Biology 2011-06-09 Michal Komorowski , Jacek Miekisz , Michael P. H. Stumpf

Intrinsic stochasticity can induce highly non-trivial effects on dynamical systems, including stochastic and coherence resonance, noise induced bistability, noise-induced oscillations, to name but a few. In this paper we revisit a mechanism…

Disordered Systems and Neural Networks · Physics 2018-07-17 Serena di Santo , Pablo Villegas , Raffaella Burioni , Miguel A. Muñoz

Biochemical reactions are fundamentally noisy at a molecular scale. This limits the precision of reaction networks, but also allows fluctuation measurements which may reveal the structure and dynamics of the underlying biochemical network.…

Biological Physics · Physics 2018-04-11 Harmen Wierenga , Pieter Rein ten Wolde , Nils B. Becker

We investigate the stochastic dynamics of a thermal machine realized by a fast-driven Otto cycle. By employing a stochastic approach, we find that system coherences strongly affect fluctuations depending on the thermodynamic current.…

Mesoscale and Nanoscale Physics · Physics 2023-06-07 Ana Laura Gramajo , Elisabetta Paladino , Jukka Pekola , Rosario Fazio

We consider stochastic dynamical systems defined by differential equations with a uniform random time delay. The latter equations are shown to be equivalent to deterministic higher-order differential equations: for an $n$-th order equation…

Statistical Mechanics · Physics 2011-10-11 P. L. Krapivsky , J. M. Luck , K. Mallick

We study the fluctuation properties of a one-dimensional many-body quantum system composed of interacting bosons, and investigate the regimes where quantum noise or, respectively, thermal excitations are dominant. For the latter we develop…

Quantum Gases · Physics 2010-07-16 H. -P. Stimming , N. J. Mauser , J. Schmiedmayer , I. E. Mazets

Fluctuation theorems make use of time reversal to make predictions about entropy production in many-body systems far from thermal equilibrium. Here we review the wide variety of distinct, but interconnected, relations that have been derived…

Statistical Mechanics · Physics 2007-08-02 R. J. Harris , G. M. Schütz

Exploiting previous results on Markovian dynamics and fluctuation theorems, we study the consequences of memory effects on single realizations of nonequilibrium processes within an open system approach. The entropy production along single…

Statistical Mechanics · Physics 2015-06-12 Bruno Leggio , Anna Napoli , Heinz-Peter Breuer , Antonino Messina

In this note we discuss a paradigmatic example of interacting particles subject to non conservative external forces and to the action of thermostats consisting of external (finite) reservoirs of particles. We then consider a model of…

Statistical Mechanics · Physics 2009-11-11 F. Bonetto , G. Gallavotti , A. Giuliani , F. Zamponi

A natural phenomenon occurring in a living system is an outcome of the dynamics of the specific biological network underlying the phenomenon. The collective dynamics have both deterministic and stochastic components. The stochastic nature…

Statistical Mechanics · Physics 2023-09-01 Indrani Bose

Mesoscopic active systems exhibit various unique behaviours - absent in passive systems - due to the forces generated by the corresponding constituents by converting their available free energies. However, estimating these forces - which…

"\textit{The noise is the signal}"[R. Landauer, Nature \textbf{392}, 658 (1998)] emphasizes the rich information content encoded in fluctuations. This paper assesses the dynamical role of fluctuations of a quantum system driven far from…

Quantum Physics · Physics 2015-03-10 Yi-Jen Chen , Stefan Pabst , Zheng Li , Oriol Vendrell , Robin Santra

We report the statistical properties of the fluctuations of the energy flux in an electronic RC circuit driven with a stochastic voltage. The fluctuations of the power injected in the circuit are measured as a function of the damping rate…

Statistical Mechanics · Physics 2009-05-06 Claudio Falcón , Eric Falcon

Protein folding is a universal process, very fast and accurate, which works consistently (as it should be) in a wide range of physiological conditions. The present work is based on three premises, namely: ($i$) folding reaction is a process…

Biological Physics · Physics 2015-05-20 J. P. Dal Molin , M. A. A. da Silva , A. Caliri

The effect of a change of noise amplitudes in overdamped diffusive systems is linked to their unperturbed behavior by means of a nonequilibrium fluctuation-response relation. This formula holds also for systems with state-independent…

Statistical Mechanics · Physics 2017-06-13 Cem Yolcu , Antoine Bérut , Gianmaria Falasco , Artyom Petrosyan , Sergio Ciliberto , Marco Baiesi

Biodiversity and extinction are central issues in evolution. Dynamical balance among different species in ecosystems is often described by deterministic replicator equations with moderate success. However, fluctuations are inevitable,…

Populations and Evolution · Quantitative Biology 2014-11-25 Tsung-Cheng Lu , Yi-Ko Chen , Hsiu-Hau Lin , Chun-Chung-Chen

The concentration of intracellular calcium ion (Ca$^{2+}$) exhibits complex oscillations, including bursting and chaos, as observed experimentally. These dynamics are influenced by inherent fluctuations within cells, which serve as crucial…

Adaptation and Self-Organizing Systems · Physics 2024-06-24 Athokpam Langlen Chanu , R. K. Brojen Singh , Jae-Hyung Jeon

We study the effects of intrinsic noise on chemical reaction systems, which in the deterministic limit approach a limit cycle in an oscillatory manner. Previous studies of systems with an oscillatory approach to a fixed point have shown…

Statistical Mechanics · Physics 2015-05-13 Richard P. Boland , Tobias Galla , Alan J. McKane