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Related papers: Mathematical models for nonlinear ultrasound contr…

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The oscillations of ultrasound contrast agents are of particular importance to the understanding of the propagation of acoustic waves in the bubbly liquids (suspensions of ultrasound contrast agents). Acoustic waves propagating in bubbly…

Fluid Dynamics · Physics 2018-10-05 Lang Xia

Microbubbles - used as contrast agents in ultrasound imaging - are important tools in biomedical research, having been used together with ultrasound to develop significant diagnostic and therapeutic techniques. It has been suggested that…

Medical Physics · Physics 2022-11-23 Prashant Pandey

Ultrasound contrast agents have been recently utilized in therapeutical implementations for targeted delivery of pharmaceutical substances. Radial pulsations of the encapsulated microbubbles under the action of an ultrasound field are…

Soft Condensed Matter · Physics 2018-11-29 Farzan Ghalichi , Sohrab Behnia , Farshad Mottaghi , Mohammad Yahyavi

Harmonic generation plays a crucial role in contrast-enhanced ultrasound, both for imaging and therapeutic applications. However, accurately capturing these nonlinear effects is computationally very demanding when using traditional…

Numerical Analysis · Mathematics 2026-02-17 Vanja Nikolić , Teresa Rauscher

The scattering of ultrasound from bubbles of micrometer-sized radius, such as used in contrast enhancers for ultrasound diagnostics, is studied. We show that sound scattering and ``active'' emission of sound from oscillating bubbles are not…

Soft Condensed Matter · Physics 2009-10-31 Sascha Hilgenfeldt , Detlef Lohse , Michael Zomack

We analyze mathematically the acoustic imaging modality using bubbles as contrast agents. These bubbles are modeled by mass densities and bulk moduli enjoying contrasting scales. These contrasting scales allow them to resonate at certain…

Analysis of PDEs · Mathematics 2020-04-17 Alexander Dabrowski , Ahcene Ghandriche , Mourad Sini

An ideal contrast-enhanced ultrasound image should display microbubble-induced nonlinearities while avoiding wave propagation nonlinearities. One of the most successful ultrasound pulse sequences to disentangle these nonlinear effects…

Medical Physics · Physics 2024-05-16 A. Matalliotakis , D. Maresca , M. D. Verweij

Acoustic microstreaming has several industrial, therapeutic, and biomedical applications - Acoustic cleaning, micromixing, microfluid transport, hemolysis, sonoporation. The acoustic microstreaming due to the oscillation of ultrasound…

Fluid Dynamics · Physics 2022-01-19 Nima Mobadersany

The attenuation of small-amplitude acoustic waves in a suspension containing ultrasound contrast agents (UCAs, coated microbubbles) is determined by the linear oscillation of the UCAs in the medium, which can be estimated via a linear…

Fluid Dynamics · Physics 2019-08-26 Lang Xia

Understanding the ultrasound pressure-driven dynamics of microbubbles confined in viscoelastic materials is relevant for multiple biomedical applications, ranging from contrast-enhanced ultrasound imaging to ultrasound-assisted drug…

Contrast microbubbles (contrast agents) were initially developed to increase the contrast of the image in ultrasound imaging. These microbubbles consist of a gas core encapsulated by a layer of protein or lipid to stabilize them against…

Medical Physics · Physics 2018-02-26 Nima Mobadersany , Kausik Sarkar

The acoustic nonlinearity parameter B/A plays a significant role in the characterization of acoustic properties of various biomaterials and biological tissues. It has the potential to be a favorable imaging modality in contrast ultrasound…

Fluid Dynamics · Physics 2019-08-16 Lang Xia

Understanding the shell rheology of ultrasound contrast agent microbubbles is vital for anticipating their bioeffects in clinical practice. Past studies using sophisticated acoustic and optical techniques have made enormous progress in this…

Fluid Dynamics · Physics 2023-08-14 Marco Cattaneo , Outi Supponen

Ultrasound localization microscopy offers new radiation-free diagnostic tools for vascular imaging deep within the tissue. Sequential localization of echoes returned from inert microbubbles with low-concentration within the bloodstream…

Medical Physics · Physics 2018-04-11 Oren Solomon , Ruud J. G. van Sloun , Hessel Wijkstra , Massimo Mischi , Yonina C. Eldar

Contrast-enhanced ultrasound (CEUS) presents distinct advantages in diagnostic echography. Utilizing microbubbles (MBs) as conventional contrast agents enhances vascular visualization and organ perfusion, facilitating real-time,…

Medical Physics · Physics 2024-12-04 Agisilaos Matalliotakis , Martin D. Verweij

Ultrasound offers promising applications in biology and chemistry, but quantifying local ultrasound conditions remains challenging due to the lack of non-invasive measurement tools. We introduce antibubbles as novel optical reporters of…

The field of contrast-enhanced ultrasound (CEUS) combines nonlinear, resonant microbubbles (MBs) with dedicated pulse sequences to reveal the vascular function of organs. Clinical ultrasound contrast agents consist of polydisperse MB…

Medical Physics · Physics 2024-09-30 Agisilaos Matalliotakis , Rick Waasdorp , Martin D. Verweij , David Maresca

Monodisperse microbubble ultrasound contrast agents have been proposed to further increase the signal-to-noise-ratio of contrast enhanced ultrasound imaging. Here, the sensitivity of a polydisperse preclinical agent was compared…

Medical Physics · Physics 2018-06-13 Tim Segers , Pieter Kruizinga , Maarten Kok , Guillaume Lajoinie , Nico de Jong , Michel Versluis

We consider an inverse problem arising in nonlinear ultrasound imaging. The propagation of ultrasound waves is modeled by a quasilinear wave equation. We make measurements at the boundary of the medium encoded in the Dirichlet-to-Neumann…

Analysis of PDEs · Mathematics 2022-03-08 Gunther Uhlmann , Yang Zhang

The attenuation of low-intensity acoustic waves in the suspension of ultrasound contrast agents (UCAs, microbubbles) is determined by the oscillation of the microbubbles in the medium. This bubble-induced attenuation is a linear phenomenon…

Fluid Dynamics · Physics 2019-08-23 Lang Xia
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