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Related papers: Mathematical models for nonlinear ultrasound contr…

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A photoacoustic contrast mechanism is presented based on the photoacoustic fluctuations induced by microbubbles flowing inside a micro vessel filled with a continuous absorber. It is demonstrated that the standard deviation of a homogeneous…

While the ultrasound and cavitation based therapies have mushroomed over the years, there is a lack of online monitoring the cavitation bubble dynamics in biological tissue. {\color{black}Here we demonstrate that with ultrasonic plane wave…

Fluid Dynamics · Physics 2023-05-26 S. Izak Ghasemian , F. Reuter , C. D. Ohl

Acoustic droplet vaporization denotes the phase-change of micron- and sub-micron-sized droplets upon the application of high-amplitude ultrasound. The asymmetric collapse of the incepted vapor bubbles within the droplets can give rise to…

Fluid Dynamics · Physics 2026-05-11 Anunay Prasanna , Samuele Fiorini , Gazendra Shakya , Outi Supponen

Mechanisms for non-invasive target drug delivery using microbubbles and ultrasound have attracted growing interest. Microbubbles can be loaded with a therapeutic payload and tracked via ultrasound imaging to selectively release their…

Medical Physics · Physics 2019-02-07 S. Harput , L. Nie , D. M. J. Cowell , T. Carpenter , B. Raiton , J. McLaughlan , S. Freear

An antibubble is a gas bubble with a liquid droplet inside. Antibubbles have a potential role in ultrasonic imaging, ultrasound-guided drug delivery, and hydrocarbon leakage detection. The liquid core droplets inside antibubbles can be…

We study nonlinear dynamics of two coupled contrast agents that are micro-meter size gas bubbles encapsulated into a viscoelastic shell. Such bubbles are used for enhancing ultrasound visualization of blood flow and have other promising…

Dynamical Systems · Mathematics 2019-07-24 Ivan R. Garashchuk , Dmitry I. Sinelshchikov , Alexey O. Kazakov , Nikolay A. Kudryashov

Acoustic characterization of ultrasound contrast agents (UCAs, coated microbubbles) relies on the attenuation theory that assumes the UCAs oscillate linearly at sufficiently low excitation pressures. Effective shell parameters of the UCAs…

Fluid Dynamics · Physics 2020-04-23 Lang Xia

Understanding the dynamics of instabilities along fluid-solid interfaces is critical for the efficacy of focused ultrasound therapy tools (e.g., histotripsy) and microcavitation rheometry techniques. Non-uniform pressure fields generated by…

Motivated by simulations of ultrasound-enhanced drug delivery, this work presents the numerical analysis of a mathematical model that captures the influence of ultrasound waves on the diffusivity of the drug. The system under study consists…

Numerical Analysis · Mathematics 2026-03-10 Femke de Wit , Vanja Nikolić

Results of the measurements of sound speed and attenuation in a bubbly medium are reported. Monodisperse bubble solutions are sonicated with broadband ultrasound pulses with pressure amplitudes ranging between 12.5-100 kPa. Fundamental…

Fluid Dynamics · Physics 2018-11-20 A. J. Sojahrood , Q. Li , H. Haghi , R. Karshafian , T. M. Porter , M. C. Kolios

The bubbles involved in sonochemistry and other applications of cavitation oscillate inertially. A correct estimation of the wave attenuation in such bubbly media requires a realistic estimation of the power dissipated by the oscillation of…

Fluid Dynamics · Physics 2013-02-26 Olivier Louisnard

We investigate a nonlinear multiphysics model motivated by ultrasound-enhanced drug delivery. The acoustic pressure field is modeled by Westervelt's quasilinear wave equation to adequately capture the nonlinear effects in ultrasound…

Analysis of PDEs · Mathematics 2024-12-11 Julio Careaga , Vanja Nikolić , Belkacem Said-Houari

The importance of ultrasound is well established in the imaging of human tissue. In order to enhance image quality by exploiting nonlinear effects, recently techniques such as harmonic imaging and nonlinearity parameter tomography have been…

Analysis of PDEs · Mathematics 2025-02-13 Barbara Kaltenbacher

We study the time-domain acoustic wave propagation in the presence of a micro-bubble. This micro-bubble is characterized by a mass density and bulk modulus which are both very small as compared to the ones of the background vacuum. The goal…

Analysis of PDEs · Mathematics 2023-12-13 Arpan Mukherjee , Mourad Sini

Ultrasound contrast agents comprise gas microbubbles surrounded by stabilising elastic or viscoelastic shells. Microbubbles containing liquid or solid cores are referred to as antibubbles. The manufacturing process of long-lived antibubbles…

Subharmonics emitted from microbubble-based ultrasound contrast agents (UCA) are considered as a noninvasive indicator for diagnostic applications in medical fields. Contrast ultrasound imaging using the modality of subharmonics could be…

Medical Physics · Physics 2021-04-13 Lang Xia

Superheated perfluorocarbon nanodroplets are emerging ultrasound imaging contrast agents boasting biocompatible components, unique phase-change dynamics, and therapeutic loading capabilities. Upon exposure to a sufficiently high intensity…

Medical Physics · Physics 2021-03-31 Austin Van Namen , Sidhartha Jandhyala , Tomas Jordan , Geoffrey Luke

Ultrasound-matter interactions underpin numerous biomedical and soft-matter applications, yet simulating these phenomena is challenging due to the large separation of viscous and sonic time scales. Continuum methods capture large-scale wave…

Soft Condensed Matter · Physics 2026-02-18 Urban Čoko , Tilen Potisk , Matej Praprotnik

Focused ultrasound stimulated microbubbles have been shown to be capable of inducing blood flow shutdown and necrosis in a range of tissue types in an approach termed antivascular ultrasound or mechanical ablation. In oncology, this…

Medical Physics · Physics 2022-10-17 Xiaoxiao Zhao , Carly Pellow , David E. Goertz

Ultrasonic irradiation of liquids, such as water-alcohol solutions, results in cavitation or the formation of small bubbles. Cavitation bubbles are generated in real solutions without the use of optical traps making our system as close to…