English
Related papers

Related papers: scASDC: Attention Enhanced Structural Deep Cluster…

200 papers

AI-driven drug response prediction holds great promise for advancing personalized cancer treatment. However, the inherent heterogenity of cancer and high cost of data generation make accurate prediction challenging. In this study, we…

Machine Learning · Computer Science 2025-05-14 Till Rossner , Ziteng Li , Jonas Balke , Nikoo Salehfard , Tom Seifert , Ming Tang

Inferring gene regulatory networks (GRNs) from single-cell RNA sequencing (scRNA-seq) data is a complex challenge that requires capturing the intricate relationships between genes and their regulatory interactions. In this study, we tackle…

Machine Learning · Computer Science 2024-07-26 Sindhura Kommu , Yizhi Wang , Yue Wang , Xuan Wang

Deep learning has become a powerful tool for medical image analysis; however, conventional Convolutional Neural Networks (CNNs) often fail to capture the fine-grained and complex features critical for accurate diagnosis. To address this…

Computer Vision and Pattern Recognition · Computer Science 2025-09-09 Zahid Ullah , Minki Hong , Tahir Mahmood , Jihie Kim

As a powerful tool for characterizing cellular subpopulations and cellular heterogeneity, single cell RNA sequencing (scRNA-seq) technology offers advantages of high throughput and multidimensional analysis. However, the process of data…

Machine Learning · Computer Science 2024-11-19 Zhuorui Cui , Shengze Dong , Ding Liu

Existing graph clustering networks heavily rely on a predefined yet fixed graph, which can lead to failures when the initial graph fails to accurately capture the data topology structure of the embedding space. In order to address this…

Machine Learning · Computer Science 2023-11-15 Zhihao Peng , Hui Liu , Yuheng Jia , Junhui Hou

This paper introduces a novel approach to speaker-attributed ASR transcription using a neural clustering method. With a parallel processing mechanism, diarisation and ASR can be applied simultaneously, helping to prevent the accumulation of…

Audio and Speech Processing · Electrical Eng. & Systems 2024-09-04 Xianrui Zheng , Guangzhi Sun , Chao Zhang , Philip C. Woodland

Traditional clustering methods often perform clustering with low-level indiscriminative representations and ignore relationships between patterns, resulting in slight achievements in the era of deep learning. To handle this problem, we…

Machine Learning · Computer Science 2019-05-07 Jianlong Chang , Yiwen Guo , Lingfeng Wang , Gaofeng Meng , Shiming Xiang , Chunhong Pan

Clustering high-dimensional spatiotemporal data using an unsupervised approach is a challenging problem for many data-driven applications. Existing state-of-the-art methods for unsupervised clustering use different similarity and distance…

Machine Learning · Computer Science 2023-09-15 Omar Faruque , Francis Ndikum Nji , Mostafa Cham , Rohan Mandar Salvi , Xue Zheng , Jianwu Wang

Credit scoring models, which are among the most potent risk management tools that banks and financial institutes rely on, have been a popular subject for research in the past few decades. Accordingly, many approaches have been developed to…

Machine Learning · Computer Science 2021-08-19 Mahsan Abdoli , Mohammad Akbari , Jamal Shahrabi

Deep graph clustering, which aims to reveal the underlying graph structure and divide the nodes into different clusters without human annotations, is a fundamental yet challenging task. However, we observed that the existing methods suffer…

Computer Vision and Pattern Recognition · Computer Science 2022-02-28 Yue Liu , Sihang Zhou , Xinwang Liu , Wenxuan Tu , Xihong Yang

Deep learning has empowered analysis for single-cell sequencing data in many ways and has generated deep understanding about a range of complex cellular systems. As the booming single-cell sequencing technologies brings the surge of high…

Genomics · Quantitative Biology 2021-04-27 Yang Xu , Andrew Jeremiah Strick

Clustering of single-cell RNA sequencing (scRNA-seq) datasets can give key insights into the biological functions of cells. Therefore, it is not surprising that network-based community detection methods (one of the better clustering…

Methodology · Statistics 2026-02-17 Chetkar Jha , Mingyao Li , Ian Barnett

The incidence and mortality rates of malignant tumors, such as acute leukemia, have risen significantly. Clinically, hospitals rely on cytological examination of peripheral blood and bone marrow smears to diagnose malignant tumors, with…

Image and Video Processing · Electrical Eng. & Systems 2024-10-14 Yifei Chen , Zhu Zhu , Shenghao Zhu , Linwei Qiu , Binfeng Zou , Fan Jia , Yunpeng Zhu , Chenyan Zhang , Zhaojie Fang , Feiwei Qin , Jin Fan , Changmiao Wang , Yu Gao , Gang Yu

Clustering algorithms are fundamental tools across many fields, with density-based methods offering particular advantages in identifying arbitrarily shaped clusters and handling noise. However, their effectiveness is often limited by the…

Machine Learning · Computer Science 2025-12-01 Meysam Shirdel Bilehsavar , Razieh Ghaedi , Samira Seyed Taheri , Xinqi Fan , Christian O'Reilly

Single-cell RNA sequencing (scRNA-seq) has emerged as a transformative technology, offering unparalleled insights into the intricate landscape of cellular diversity and gene expression dynamics. The analysis of scRNA-seq data poses…

Molecular Networks · Quantitative Biology 2023-12-19 Hongsong Feng , Sean Cottrell , Yuta Hozumi , Guo-Wei Wei

Spectral clustering is a powerful technique for clustering high-dimensional data, utilizing graph-based representations to detect complex, non-linear structures and non-convex clusters. The construction of a similarity graph is essential…

Machine Learning · Computer Science 2025-01-27 Kamal Berahmand , Farid Saberi-Movahed , Razieh Sheikhpour , Yuefeng Li , Mahdi Jalili

The recent advances in single-cell technologies have enabled us to profile genomic features at unprecedented resolution and datasets from multiple domains are available, including datasets that profile different types of genomic features…

Machine Learning · Statistics 2020-06-09 Pengcheng Zeng , Zhixiang Lin

Modern high-throughput sequencing technologies have enabled us to profile multiple molecular modalities from the same single cell, providing unprecedented opportunities to assay celluar heterogeneity from multiple biological layers.…

Machine Learning · Statistics 2022-05-20 Pengcheng Zeng , Zhixiang Lin

Compared to unsupervised domain adaptation, semi-supervised domain adaptation (SSDA) aims to significantly improve the classification performance and generalization capability of the model by leveraging the presence of a small amount of…

Computer Vision and Pattern Recognition · Computer Science 2024-01-23 Jichang Li , Guanbin Li , Yizhou Yu

Clustering single-cell RNA sequence (scRNA-seq) data poses statistical and computational challenges due to their high-dimensionality and data-sparsity, also known as `dropout' events. Recently, Regularized Auto-Encoder (RAE) based deep…

Machine Learning · Computer Science 2021-07-19 Arnab Kumar Mondal , Himanshu Asnani , Parag Singla , Prathosh AP