Related papers: scASDC: Attention Enhanced Structural Deep Cluster…
Self-supervised learning (SSL) has proven to be a powerful approach for extracting biologically meaningful representations from single-cell data. To advance our understanding of SSL methods applied to single-cell data, we present…
Single-cell RNA sequencing (scRNA-seq) has made significant strides in unraveling the intricate cellular diversity within complex tissues. This is particularly critical in the brain, presenting a greater diversity of cell types than other…
Recent advancements in single-cell genomics necessitate precision in gene panel selection to interpret complex biological data effectively. Those methods aim to streamline the analysis of scRNA-seq data by focusing on the most informative…
Graph clustering, which learns the node representations for effective cluster assignments, is a fundamental yet challenging task in data analysis and has received considerable attention accompanied by graph neural networks in recent years.…
Spectral clustering is a leading clustering method. Two of its major shortcomings are the disjoint optimization process and the limited representation capacity. To address these issues, we propose a deep spectral clustering model (named…
Change detection, which aims to distinguish surface changes based on bi-temporal images, plays a vital role in ecological protection and urban planning. Since high resolution (HR) images cannot be typically acquired continuously over time,…
Spatial transcriptomics clustering is pivotal for identifying cell subpopulations by leveraging spatial location information. While recent graph-based methods modeling cell-cell interactions have improved clustering accuracy, they remain…
Many complex systems in the real world can be characterized by attributed networks. To mine the potential information in these networks, deep embedded clustering, which obtains node representations and clusters simultaneously, has been paid…
Recent advances in high-resolution sequencing have paved the way for population-scale analysis in single-cell RNA-sequencing (scRNA-seq) data. scRNA-seq data, in particular, have proven to be extremely powerful in profiling a variety of…
Graph convolutional network (GCN) is a powerful model studied broadly in various graph structural data learning tasks. However, to mitigate the over-smoothing phenomenon, and deal with heterogeneous graph structural data, the design of GCN…
Single-cell RNA sequencing (scRNA-seq) has revealed complex cellular heterogeneity, but recent studies emphasize that understanding biological function also requires modeling cell-cell communication (CCC), the signaling interactions…
ASD is a complicated neurodevelopmental disorder marked by variation in symptom presentation and neurological underpinnings, making early and objective diagnosis extremely problematic. This paper presents a Graph Convolutional Network (GCN)…
Background: Single-cell RNA sequencing (scRNA-seq) is a powerful profiling technique at the single-cell resolution. Appropriate analysis of scRNA-seq data can characterize molecular heterogeneity and shed light into the underlying cellular…
Repetitive DNA (repeats) poses significant challenges for accurate and efficient genome assembly and sequence alignment. This is particularly true for metagenomic data, where genome dynamics such as horizontal gene transfer, gene…
The exploration of cellular heterogeneity within the tumor microenvironment (TME) via single-cell RNA sequencing (scRNA-seq) is essential for understanding cancer progression and response to therapy. Current scRNA-seq approaches, however,…
Rapid advancements in high-throughput single-cell RNA-seq (scRNA-seq) technologies and experimental protocols have led to the generation of vast amounts of genomic data that populates several online databases and repositories. Here, we…
The high dimensional and semantically complex nature of textual Big data presents significant challenges for text clustering, which frequently lead to suboptimal groupings when using conventional techniques like k-means or hierarchical…
Recent advances in technology have enabled the measurement of RNA levels for individual cells. Compared to traditional tissue-level bulk RNA-seq data, single cell sequencing yields valuable insights about gene expression profiles for…
Single-cell RNA sequencing (scRNA-seq) provides a high throughput, quantitative and unbiased framework for scientists in many research fields to identify and characterize cell types within heterogeneous cell populations from various…
Channel pruning is a powerful technique to reduce the computational overhead of deep neural networks, enabling efficient deployment on resource-constrained devices. However, existing pruning methods often rely on local heuristics or…