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The EMCCD is a type of CCD that delivers fast readout times and negligible readout noise, making it an ideal detector for high frame rate applications which improve resolution, like lucky imaging or shift-and-add. This improvement in…

Instrumentation and Methods for Astrophysics · Physics 2012-04-06 Kennet B. W. Harpsøe , Uffe G. Jørgensen , Michael I. Andersen , Frank Grundahl

Due to the low X-ray photon utilization efficiency and low measurement sensitivity of the electron multiplying charge coupled device (EMCCD) camera setup, the collimator based narrow beam X-ray luminescence computed tomography (XLCT)…

Medical Physics · Physics 2018-03-14 Wei Zhang , Michael C Lun , Alex Anh-Tu Nguyen , Changqing Li

Spectral imaging is the acquisition of multiple images of an object at different energy spectra. In mammography, dual-energy imaging (spectral imaging with two energy levels) has been investigated for several applications, in particular…

Medical Physics · Physics 2021-02-02 Karl Berggren , Mats Danielsson , Erik Fredenberg

Many optical measurement techniques, such as light scattering from wavelength-scale particles or detecting motion from a surface with an optical lever, encode information in a complex radiation pattern. Extracting all available information…

Quantum Physics · Physics 2025-12-22 Youssef Tawfik , Shan Hao , Thomas P. Purdy

Accurate attenuation and scatter corrections are crucial in positron emission tomography (PET) imaging for accurate visual interpretation and quantitative analysis. Traditional methods relying on computed tomography (CT) or magnetic…

Medical Physics · Physics 2025-11-14 Min Jeong Cho , Hyeong Seok Shim , Sungyu Kim , Jae Sung Lee

The new generation of multi-PetaWatt laser facilities will allow tests of Strong Field QED, as well as provide an opportunity for novel photon and lepton sources. The first experiments are planned to study the (nearly) head-on scattering of…

Plasma Physics · Physics 2024-02-27 Óscar Amaro , Marija Vranic

In distributed radar systems, when several transmitters radiate simultaneously, the reflected signals need to be distinguished at the receivers to detect various targets. If the transmit signals are in different frequency bands, they…

Signal Processing · Electrical Eng. & Systems 2024-01-02 Gokularam Muthukrishnan , S. Sruti , K. Giridhar

X-ray Computed Tomography (CT) is an important tool in medical imaging to obtain a direct visualization of patient anatomy. However, the x-ray radiation exposure leads to the concern of lifetime cancer risk. Low-dose CT scan can reduce the…

Medical Physics · Physics 2018-10-30 Guoyang Ma , Chenyang Shen , Xun Jia

Diverse searches for direct dark matter (DM) in effective electromagnetic and leptophilic interactions resulting from new physics, as well as Weakly Interacting Massive Particles (WIMPs) with unconventional electronic recoils, are…

In a standard computed tomography (CT) image, pixels having the same Hounsfield Units (HU) can correspond to different materials and it is therefore challenging to differentiate and quantify materials. Dual-energy CT (DECT) is desirable to…

Medical Physics · Physics 2020-10-27 Wei Zhao , Tianling Lyu , Yang Chen , Lei Xing

Computed tomography (CT) serves as an effective tool for lung cancer screening, diagnosis, treatment, and prognosis, providing a rich source of features to quantify temporal and spatial tumor changes. Nonetheless, the diversity of CT…

Image and Video Processing · Electrical Eng. & Systems 2023-10-10 Md Selim , Jie Zhang , Faraneh Fathi , Michael A. Brooks , Ge Wang , Guoqiang Yu , Jin Chen

Scattered coincidences introduce quantitative bias in positron emission tomography (PET) and must be compensated during reconstruction. Conventional scatter estimates typically rely on simplified cylindrical scanner models that omit…

We have evaluated the performance of a fine pitch CdTe Double-sided Strip Detector (CdTe-DSD), which was originally developed for the focal plane detector of a hard X-ray telescope to observe the Sun. The detector has a thickness of 750 um…

Instrumentation and Methods for Astrophysics · Physics 2020-08-04 Kento Furukawa , Shunsaku Nagasawa , Lindsay Glesener , Miho Katsuragawa , Shin'ichiro Takeda , Shin Watanabe , Tadayuki Takahashi

Multiple optical scattering occurs when light propagates in a non-uniform medium. During the multiple scattering, images were distorted and the spatial information they carried became scrambled. However, the image information is not lost…

Computer Vision and Pattern Recognition · Computer Science 2021-07-30 Xinyu Gao , Yi Li , Yanqing Qiu , Bangning Mao , Miaogen Chen , Yanlong Meng , Chunliu Zhao , Juan Kang , Yong Guo , Changyu Shen

This research considers potential dose increase in target due to cisplatin (Pt) concentration and radiation type. Cisplatin concentrations from 0.003 to 120 mM were used. Monte-Carlo simulation of Linear accelerator (Elekta Synergy) and…

Medical Physics · Physics 2020-08-26 A. A. Baulin

Objective: Cone-beam computed tomography (CBCT) provides a low-dose imaging alternative to conventional CT, but suffers from noise, scatter, and artifacts that degrade image quality. Synthetic CT (sCT) aims to translate CBCT to high-quality…

Medical Physics · Physics 2025-09-23 Alzahra Altalib , Chunhui Li , Alessandro Perelli

Numerous dual-energy CT (DECT) techniques have been developed in the past few decades. Dual-energy CT (DECT) statistical iterative reconstruction (SIR) has demonstrated its potential for reducing noise and increasing accuracy. Our lab…

Image and Video Processing · Electrical Eng. & Systems 2023-02-02 Tao Ge , Maria Medrano , Rui Liao , David G. Politte , Jeffrey F. Williamson , Bruce R. Whiting , Joseph A. O'Sullivan

Cone-beam computed tomography (CBCT) systems, with their flexibility, present a promising avenue for direct point-of-care medical imaging, particularly in critical scenarios such as acute stroke assessment. However, the integration of CBCT…

An important source of background in direct searches for low-mass dark matter particles are the energy deposits by small-angle scattering of environmental $\gamma$ rays. We report detailed measurements of low-energy spectra from Compton…

Instrumentation and Detectors · Physics 2017-08-30 K. Ramanathan , A. Kavner , A. E. Chavarria , P. Privitera , D. Amidei , T. -L. Chou , A. Matalon , R. Thomas , J. Estrada , J. Tiffenberg , J. Molina

Spectral computed tomography (CT) has recently emerged as an advanced version of medical CT and significantly improves conventional (single-energy) CT. Spectral CT has two main forms: dual-energy computed tomography (DECT) and…