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Related papers: BioMamba: Domain-Adaptive Biomedical Language Mode…

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Pre-trained language models (PLMs) have proven to be effective for document re-ranking task. However, they lack the ability to fully interpret the semantics of biomedical and health-care queries and often rely on simplistic patterns for…

Computation and Language · Computer Science 2023-05-09 Deepak Gupta , Dina Demner-Fushman

Domain adaptive pretraining, i.e. the continued unsupervised pretraining of a language model on domain-specific text, improves the modelling of text for downstream tasks within the domain. Numerous real-world applications are based on…

Computation and Language · Computer Science 2021-09-15 Rasmus Kær Jørgensen , Mareike Hartmann , Xiang Dai , Desmond Elliott

Recently, the Mamba architecture based on state space models has demonstrated remarkable performance in a series of natural language processing tasks and has been rapidly applied to remote sensing change detection (CD) tasks. However, most…

Computer Vision and Pattern Recognition · Computer Science 2025-05-20 Haotian Zhang , Keyan Chen , Chenyang Liu , Hao Chen , Zhengxia Zou , Zhenwei Shi

The availability of biomedical text data and advances in natural language processing (NLP) have made new applications in biomedical NLP possible. Language models trained or fine tuned using domain specific corpora can outperform general…

Computation and Language · Computer Science 2021-07-12 Usman Naseem , Adam G. Dunn , Matloob Khushi , Jinman Kim

Large language models exhibit promising general capabilities but often lack specialized knowledge for domain-specific tasks. Developing domain experts from a base model enables a range of applications without prohibitive training costs.…

Computation and Language · Computer Science 2023-11-02 Zhen Guo , Yining Hua

Existing Protein Language Models (PLMs) often suffer from limited adaptability to multiple tasks and exhibit poor generalization across diverse biological contexts. In contrast, general-purpose Large Language Models (LLMs) lack the…

Machine Learning · Computer Science 2026-02-23 Yujia Wang , Jihong Guan , Wengen Li , Shuigeng Zhou , Xuhong Wang

Most biomedical pretrained language models are monolingual and cannot handle the growing cross-lingual requirements. The scarcity of non-English domain corpora, not to mention parallel data, poses a significant hurdle in training…

Computation and Language · Computer Science 2023-11-21 Lei Geng , Xu Yan , Ziqiang Cao , Juntao Li , Wenjie Li , Sujian Li , Xinjie Zhou , Yang Yang , Jun Zhang

Conformer and Mamba have achieved strong performance in speech modeling but face limitations in speaker diarization. Mamba is efficient but struggles with local details and nonlinear patterns. Conformer's self-attention incurs high memory…

Sound · Computer Science 2026-01-28 Zhen Liao , Gaole Dai , Mengqiao Chen , Wenqing Cheng , Wei Xu

Protein function prediction is a pivotal task in drug discovery, significantly impacting the development of effective and safe therapeutics. Traditional machine learning models often struggle with the complexity and variability inherent in…

Machine Learning · Computer Science 2024-09-24 Bohao Xu , Yingzhou Lu , Yoshitaka Inoue , Namkyeong Lee , Tianfan Fu , Jintai Chen

Recently, Large Language Models (LLM) have demonstrated impressive capability to solve a wide range of tasks. However, despite their success across various tasks, no prior work has investigated their capability in the biomedical domain yet.…

Computation and Language · Computer Science 2024-02-21 Israt Jahan , Md Tahmid Rahman Laskar , Chun Peng , Jimmy Huang

Multimodal image fusion aims to integrate information from different imaging techniques to produce a comprehensive, detail-rich single image for downstream vision tasks. Existing methods based on local convolutional neural networks (CNNs)…

Computer Vision and Pattern Recognition · Computer Science 2025-02-04 Xinyu Xie , Yawen Cui , Tao Tan , Xubin Zheng , Zitong Yu

In recent years, visually-rich document understanding has attracted increasing attention. Transformer-based pre-trained models have become the mainstream approach, yielding significant performance gains in this field. However, the…

Computation and Language · Computer Science 2025-02-11 Pengfei Hu , Zhenrong Zhang , Jiefeng Ma , Shuhang Liu , Jun Du , Jianshu Zhang

Recent advances in natural language processing (NLP) have been driven bypretrained language models like BERT, RoBERTa, T5, and GPT. Thesemodels excel at understanding complex texts, but biomedical literature, withits domain-specific…

Computation and Language · Computer Science 2025-07-28 K. Sahit Reddy , N. Ragavenderan , Vasanth K. , Ganesh N. Naik , Vishalakshi Prabhu , Nagaraja G. S

Pre-training and fine-tuning have emerged as a promising paradigm across various natural language processing (NLP) tasks. The effectiveness of pretrained large language models (LLM) has witnessed further enhancement, holding potential for…

Computation and Language · Computer Science 2023-11-06 Guoxing Yang , Jianyu Shi , Zan Wang , Xiaohong Liu , Guangyu Wang

Accurate prediction of RNA-associated interactions is essential for understanding cellular regulation and advancing drug discovery. While Biological Large Language Models (BioLLMs) such as ESM-2 and RiNALMo provide powerful sequence…

Genomics · Quantitative Biology 2026-02-27 Rabeya Tus Sadia , Qiang Ye , Qiang Cheng

Mamba, a State Space Model (SSM) that accelerates training by recasting recurrence as a parallel scan, has recently emerged as a linearly-scaling alternative to self-attention. Because of its unidirectional nature, each state in Mamba only…

Computer Vision and Pattern Recognition · Computer Science 2025-11-13 Jingwei Zhang , Xi Han , Hong Qin , Mahdi S. Hosseini , Dimitris Samaras

With new sequence models like Mamba and xLSTM, several studies have shown that these models match or outperform the state-of-the-art in single-channel speech enhancement and audio representation learning. However, prior research has…

Sound · Computer Science 2026-01-22 Nikolai Lund Kühne , Jesper Jensen , Jan Østergaard , Zheng-Hua Tan

Foundation models (FMs) have exhibited remarkable performance across a wide range of downstream tasks in many domains. Nevertheless, general-purpose FMs often face challenges when confronted with domain-specific problems, due to their…

Computational Engineering, Finance, and Science · Computer Science 2023-08-22 Yizhen Luo , Jiahuan Zhang , Siqi Fan , Kai Yang , Yushuai Wu , Mu Qiao , Zaiqing Nie

The modeling of bio-molecular system across molecular scales remains a central challenge in scientific research. Large language models (LLMs) are increasingly applied to bio-molecular discovery, yet systematic evaluation across multi-scale…

Machine Learning · Computer Science 2026-04-07 Yaxin Xu , Yue Zhou , Tianyu Zhao , Fengwei An , Zhixiang Ren

This paper narrows the performance gap between small, specialized models and significantly larger general-purpose models through domain adaptation via continual pre-training and merging. We address the scarcity of specialized non-English…

Computation and Language · Computer Science 2026-04-22 Niclas Doll , Jasper Schulze Buschhoff , Shalaka Satheesh , Hammam Abdelwahab , Héctor Allende-Cid , Katrin Klug