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Related papers: BioMamba: Domain-Adaptive Biomedical Language Mode…

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Mamba extends earlier state space models (SSMs) by introducing input-dependent dynamics, and has demonstrated strong empirical performance across a range of domains, including language modeling, computer vision, and foundation models.…

Machine Learning · Computer Science 2025-05-15 Annan Yu , N. Benjamin Erichson

Large language models (LLMs) have advanced significantly due to the attention mechanism, but their quadratic complexity and linear memory demands limit their performance on long-context tasks. Recently, researchers introduced Mamba, an…

Computation and Language · Computer Science 2024-10-22 Wangjie You , Zecheng Tang , Juntao Li , Lili Yao , Min Zhang

The advent of single-cell multi-omics technologies has enabled the simultaneous profiling of diverse omics layers within individual cells. Integrating such multimodal data provides unprecedented insights into cellular identity, regulatory…

Cell Behavior · Quantitative Biology 2025-06-27 Zhen Yuan , Shaoqing Jiao , Yihang Xiao , Jiajie Peng

Transformer and its derivatives have achieved success in diverse tasks across computer vision, natural language processing, and speech processing. To reduce the complexity of computations within the multi-head self-attention mechanism in…

Audio and Speech Processing · Electrical Eng. & Systems 2025-04-29 Xiangyu Zhang , Qiquan Zhang , Hexin Liu , Tianyi Xiao , Xinyuan Qian , Beena Ahmed , Eliathamby Ambikairajah , Haizhou Li , Julien Epps

Prompt learning is one of the most effective paradigms for adapting pre-trained vision-language models (VLMs) to the biomedical image classification tasks in few shot scenarios. However, most of the current prompt learning methods only used…

Computer Vision and Pattern Recognition · Computer Science 2025-05-09 Wei Peng , Kang Liu , Jianchen Hu , Meng Zhang

The overwhelming amount of biomedical scientific texts calls for the development of effective language models able to tackle a wide range of biomedical natural language processing (NLP) tasks. The most recent dominant approaches are…

Computation and Language · Computer Science 2021-04-21 Giacomo Miolo , Giulio Mantoan , Carlotta Orsenigo

Biomedical literature often uses complex language and inaccessible professional terminologies. That is why simplification plays an important role in improving public health literacy. Applying Natural Language Processing (NLP) models to…

Computation and Language · Computer Science 2024-03-19 Zihao Li , Samuel Belkadi , Nicolo Micheletti , Lifeng Han , Matthew Shardlow , Goran Nenadic

Pretrained language models have served as important backbones for natural language processing. Recently, in-domain pretraining has been shown to benefit various domain-specific downstream tasks. In the biomedical domain, natural language…

Computation and Language · Computer Science 2022-04-25 Hongyi Yuan , Zheng Yuan , Ruyi Gan , Jiaxing Zhang , Yutao Xie , Sheng Yu

Pre-trained language models (PLMs) have been the de facto paradigm for most natural language processing (NLP) tasks. This also benefits biomedical domain: researchers from informatics, medicine, and computer science (CS) communities propose…

Computation and Language · Computer Science 2023-07-18 Benyou Wang , Qianqian Xie , Jiahuan Pei , Zhihong Chen , Prayag Tiwari , Zhao Li , Jie fu

In the era of digital healthcare, the huge volumes of textual information generated every day in hospitals constitute an essential but underused asset that could be exploited with task-specific, fine-tuned biomedical language representation…

Computation and Language · Computer Science 2023-07-12 Tommaso Mario Buonocore , Claudio Crema , Alberto Redolfi , Riccardo Bellazzi , Enea Parimbelli

Recently, Large Language Models (LLMs) have showcased remarkable capabilities in natural language understanding. While demonstrating proficiency in everyday conversations and question-answering situations, these models frequently struggle…

Computation and Language · Computer Science 2023-08-28 Chaoyi Wu , Weixiong Lin , Xiaoman Zhang , Ya Zhang , Yanfeng Wang , Weidi Xie

Self-supervised training of language models (LMs) has seen great success for protein sequences in learning meaningful representations and for generative drug design. Most protein LMs are based on the Transformer architecture trained on…

Biomolecules · Quantitative Biology 2025-04-03 Yingheng Wang , Zichen Wang , Gil Sadeh , Luca Zancato , Alessandro Achille , George Karypis , Huzefa Rangwala

The biomedical domain has sparked a significant interest in the field of Natural Language Processing (NLP), which has seen substantial advancements with pre-trained language models (PLMs). However, comparing these models has proven…

Accurate survival prediction in oncology requires integrating diverse imaging modalities to capture the complex interplay of tumor biology. Traditional single-modality approaches often fail to leverage the complementary insights provided by…

Computer Vision and Pattern Recognition · Computer Science 2025-03-14 Ho Hin Lee , Alberto Santamaria-Pang , Jameson Merkov , Matthew Lungren , Ivan Tarapov

Language models pretrained on text from a wide variety of sources form the foundation of today's NLP. In light of the success of these broad-coverage models, we investigate whether it is still helpful to tailor a pretrained model to the…

Computation and Language · Computer Science 2020-05-07 Suchin Gururangan , Ana Marasović , Swabha Swayamdipta , Kyle Lo , Iz Beltagy , Doug Downey , Noah A. Smith

Mamba, a special case of the State Space Model, is gaining popularity as an alternative to template-based deep learning approaches in medical image analysis. While transformers are powerful architectures, they have drawbacks, including…

Accurate medical image segmentation demands the integration of multi-scale information, spanning from local features to global dependencies. However, it is challenging for existing methods to model long-range global information, where…

Image and Video Processing · Electrical Eng. & Systems 2024-03-07 Jiarun Liu , Hao Yang , Hong-Yu Zhou , Yan Xi , Lequan Yu , Yizhou Yu , Yong Liang , Guangming Shi , Shaoting Zhang , Hairong Zheng , Shanshan Wang

Contextualized word embeddings derived from pre-trained language models (LMs) show significant improvements on downstream NLP tasks. Pre-training on domain-specific corpora, such as biomedical articles, further improves their performance.…

Computation and Language · Computer Science 2019-04-05 Qiao Jin , Bhuwan Dhingra , William W. Cohen , Xinghua Lu

The typical Selective State-Space Model (SSM) used in Mamba addresses several limitations of Transformers, such as the quadratic computational complexity with respect to sequence length and the significant memory requirements during…

Computation and Language · Computer Science 2025-10-24 Shengkun Tang , Liqun Ma , Haonan Li , Mingjie Sun , Zhiqiang Shen

Several recent works seek to develop foundation models specifically for medical applications, adapting general-purpose large language models (LLMs) and vision-language models (VLMs) via continued pretraining on publicly available biomedical…

Computation and Language · Computer Science 2024-11-21 Daniel P. Jeong , Saurabh Garg , Zachary C. Lipton , Michael Oberst