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Meeting the high data rate demands of modern applications necessitates the utilization of high-frequency spectrum bands, including millimeter-wave and sub-terahertz bands. However, these frequencies require precise alignment of narrow…

Information Theory · Computer Science 2024-12-05 Sachira Karunasena , Erfan Khordad , Thomas Drummond , Rajitha Senanayake

The throughput of electron microscopes has increased significantly in recent years, enabling detailed analysis of cell morphology and ultrastructure. Analysis of neural circuits at single-synapse resolution remains the flagship target of…

Computer Vision and Pattern Recognition · Computer Science 2019-08-07 Constantin Pape , Alex Matskevych , Adrian Wolny , Julian Hennies , Giula Mizzon , Marion Louveaux , Jacob Musser , Alexis Maizel , Detlev Arendt , Anna Kreshuk

Imaging with multiple modalities or multiple channels is becoming increasingly important for our modern society. A key tool for understanding and early diagnosis of cancer and dementia is PET-MR, a combined positron emission tomography and…

Image and Video Processing · Electrical Eng. & Systems 2020-07-24 Matthias J. Ehrhardt

Electron and x-ray microscopes allow one to image the entire, unlabeled structure of hydrated materials at a resolution well beyond what visible light microscopes can achieve. However, both approaches involve ionizing radiation, so that…

Applied Physics · Physics 2020-04-22 Ming Du , Chris Jacobsen

Medical image segmentation is important for computer-aided diagnosis. Good segmentation demands the model to see the big picture and fine details simultaneously, i.e., to learn image features that incorporate large context while keep high…

Image and Video Processing · Electrical Eng. & Systems 2021-06-03 Shaohua Li , Xiuchao Sui , Xiangde Luo , Xinxing Xu , Yong Liu , Rick Goh

Light-sheet microscopes must compromise between field of view, optical sectioning, resolution, and detection efficiency. High-numerical-aperture (NA) detection objective lenses provide high resolution but their narrow depth of field fails…

Dark-field x-ray microscopy utilizes Bragg diffraction to collect full-field x-ray images of "mesoscale" structure of ordered materials. Information regarding the structural heterogeneities and their physical implications is gleaned through…

Materials Science · Physics 2022-10-31 Omar Abulshohoud , Ishwor Poudyal , Jessica McChesney , Zhan Zhang , Zhi Qiao , Ulrich Welp , Zahir Islam

Recently, experiments have been reported where researchers were able to perform high dynamic range (HDR) tomography in a heuristic fashion, by fusing multiple tomographic projections. This approach to HDR tomography has been inspired by HDR…

Information Theory · Computer Science 2021-05-11 Matthias Beckmann , Ayush Bhandari , Felix Krahmer

Complex field imaging, which captures both the amplitude and phase information of input optical fields or objects, can offer rich structural insights into samples, such as their absorption and refractive index distributions. However,…

Optics · Physics 2024-05-30 Jingxi Li , Yuhang Li , Tianyi Gan , Che-Yung Shen , Mona Jarrahi , Aydogan Ozcan

Deep learning methods can be found in many medical imaging applications. Recently, those methods were applied directly to the RF ultrasound multi-channel data to enhance the quality of the reconstructed images. In this paper, we apply a…

Signal Processing · Electrical Eng. & Systems 2020-11-23 Nissim Peretz , Arie Feuer

Over the past few years, the combination of diffuser and near-field electron ptychography has drawn more attention by its ability to recover large field of view with few diffraction patterns. In this paper, we purpose a novel design and…

Medical image segmentation is essential for clinical applications such as disease diagnosis, treatment planning, and disease development monitoring because it provides precise morphological and spatial information on anatomical structures…

Computer Vision and Pattern Recognition · Computer Science 2026-05-01 Moin Safdar , Shahzaib Iqbal , Mubeen Ghafoor , Tariq M. Khan , Imran Razzak , Thantrira Porntaveetus , Hamid Alinejad-Rokny

Multimode fibers (MMFs) can transmit multiple guided modes simultaneously, making them a promising platform for high-resolution biomedical imaging, endoscopy and high-bandwidth optical communication. However, their complex modal behavior,…

Optics · Physics 2026-05-28 Dvir Marsh , Lior Fridman , Stav Lotan , Amit Kam , Shie Mannor , Guy Bartal

Optical imaging systems are generally limited by the depth of field because of the nature of the optics. Therefore, extending depth of field (EDoF) is a fundamental task for meeting the requirements of emerging visual applications. To solve…

Computer Vision and Pattern Recognition · Computer Science 2024-10-01 Zhilong Li , Kejun Wu , Qiong Liu , You Yang

Integration of hyperspectral imaging into fluorescence-guided neurosurgery has the potential to improve surgical decision making by providing quantitative fluorescence measurements in real-time. Quantitative fluorescence requires paired…

Computer Vision and Pattern Recognition · Computer Science 2026-01-07 Charlie Budd , Silvère Ségaud , Matthew Elliot , Graeme Stasiuk , Yijing Xie , Jonathan Shapey , Tom Vercauteren

Differential wavefront sensing is an essential technique for optimising the performance of many precision interferometric experiments. Perhaps the most extensive application of this is for alignment sensing using radio-frequency beats…

Instrumentation and Detectors · Physics 2021-05-26 Daniel D. Brown , Huy Tuong Cao , Alexei Ciobanu , Peter Veitch , David Ottaway

Sonography techniques use multiple transducer elements for tissue visualization. Signals detected at each element are sampled prior to digital beamforming. The required sampling rates are up to 4 times the Nyquist rate of the signal and…

Information Theory · Computer Science 2012-12-21 T. Chernyakova , Y. C. Eldar , R. Amit

This study introduces a novel metric, Plan Aperture Modulation (PAM), developed to quantify the modulation of radiotherapy treatment plans. PAM aims to provide a clear geometric interpretation, addressing the limitations of previous…

Medical Physics · Physics 2025-11-25 Victor Hernandez , Iñigo Lara-Aristimuño , Ruben Abella , Jordi Saez

Performing simultaneous depth-of-field (DoF) extension and edge enhancement within a single optical element remains a fundamental challenge in advanced imaging. Here, we propose a wavelength-tunable nonlocal Huygens' metasurface capable of…

Optics · Physics 2025-10-03 Kenan Guo , Yue Jiang , Shuyuan Xiao , Tingting Liu

The X-ray microscopy technique at the European X-ray free-electron laser (EuXFEL), operating at a MHz repetition rate, provides superior contrast and spatial-temporal resolution compared to typical microscopy techniques at other X-ray…

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