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Wavefront shaping systems aim to image deep into scattering tissue by reshaping incoming and outgoing light to correct aberrations caused by tissue inhomogeneity However, the desired modulation depends on the unknown tissue structure and…

Optics · Physics 2026-01-14 Sagi Monin , Marina Alterman , Anat Levin

Achieving high-precision light manipulation is crucial for delivering information through complex media with high fidelity. However, existing spatial light modulation devices face a fundamental tradeoff between speed and accuracy. Digital…

Optics · Physics 2026-03-16 Li-Yu Yu , Sixian You

X-ray imaging is the most widely used medical imaging modality. However, in the common practice, inconsistency in the initial presentation of X-ray images is a common complaint by radiologists. Different patient positions, patient habitus…

Image and Video Processing · Electrical Eng. & Systems 2025-01-22 Hongxu Yang , Najib Akram Aboobacker , Xiaomeng Dong , German Gonzalez , Lehel Ferenczi , Gopal Avinash

High-resolution optical imaging methods, such as confocal microscopy and full-field optical coherence tomography, capture flat optical sections of the sample. If the sample is curved, the optical field sections through several sample layers…

Medical Physics · Physics 2020-07-31 Viacheslav Mazlin , Kristina Irsch , Michel Paques , Mathias Fink , Albert Claude Boccara

Methods for resolving the 3D microstructure of the brain typically start by thinly slicing and staining the brain, and then imaging each individual section with visible light photons or electrons. In contrast, X-rays can be used to image…

Spectral imaging is a fundamental diagnostic technique with widespread application. Conventional spectral imaging approaches have intrinsic limitations on spatial and spectral resolutions due to the physical components they rely on. To…

Image and Video Processing · Electrical Eng. & Systems 2021-06-07 Figen S. Oktem , Oğuzhan Fatih Kar , Can Deniz Bezek , Farzad Kamalabadi

We report a new coherent imaging technique, termed ptychographic structured modulation (PSM), for quantitative super-resolution microscopy. In this technique, we place a thin diffuser (i.e., a scattering lens) in between the sample and the…

Image and Video Processing · Electrical Eng. & Systems 2019-07-26 Pengming Song , Shaowei Jiang , He Zhang , Zichao Bian , Chengfei Guo , Kazunori Hoshino , Guoan Zheng

We show that the modulation of the phases of the laser beams of ultra-short pulses leads to modulation of the two photon fluorescence intensity. The phase modulation technique when used in multi-photon microscopy can improve the signal to…

Optics · Physics 2015-03-12 Khadga Jung Karki , Mohammed Abdellah , Tonu Pullerits

Brain metastasis segmentation poses a significant challenge in medical imaging due to the complex presentation and variability in size and location of metastases. In this study, we first investigate the impact of different imaging…

Image and Video Processing · Electrical Eng. & Systems 2024-07-22 Yousef Sadegheih , Dorit Merhof

Deformable registration of magnetic resonance images between patients with brain tumors and healthy subjects has been an important tool to specify tumor geometry through location alignment and facilitate pathological analysis. Since tumor…

Image and Video Processing · Electrical Eng. & Systems 2021-01-19 Xiaofeng Liu , Fangxu Xing , Chao Yang , C. -C. Jay Kuo , Georges ElFakhri , Jonghye Woo

The living body is composed of innumerable fine and complex structures and although these structures have been studied in the past, a vast amount of information pertaining to them still remains unknown. When attempting to observe these…

Medical Physics · Physics 2021-11-30 Raku Son , Kenji Yamazawa , Akiko Oguchi , Mitsuo Suga , Masaru Tamura , Yasuhiro Murakawa , Satoshi Kume

Investigating the structure of matter at the nanoscale non destructively is a key capability enabled by X-ray imaging. One of the most powerful nano-imaging methods is X-ray ptychography, a coherent diffraction imaging technique that has…

Magnetic resonance imaging (MRI) is critically important for brain mapping in both scientific research and clinical studies. Precise segmentation of brain tumors facilitates clinical diagnosis, evaluations, and surgical planning. Deep…

Image and Video Processing · Electrical Eng. & Systems 2023-05-01 Rui Nian , Guoyao Zhang , Yao Sui , Yuqi Qian , Qiuying Li , Mingzhang Zhao , Jianhui Li , Ali Gholipour , Simon K. Warfield

Segmentation of brain magnetic resonance images (MRI) into anatomical regions is a useful task in neuroimaging. Manual annotation is time consuming and expensive, so having a fully automated and general purpose brain segmentation algorithm…

Computer Vision and Pattern Recognition · Computer Science 2021-12-10 Yu Yan , Yael Balbastre , Mikael Brudfors , John Ashburner

The examination of histopathology images is considered to be the gold standard for the diagnosis and stratification of cancer patients. A key challenge in the analysis of such images is their size, which can run into the gigapixels and can…

Image and Video Processing · Electrical Eng. & Systems 2021-09-09 Joseph Boyd , Mykola Liashuha , Eric Deutsch , Nikos Paragios , Stergios Christodoulidis , Maria Vakalopoulou

For over a century diffraction theory has been thought to limit the resolution of focusing and imaging in the optical domain. The size of the smallest spot achievable is inversely proportional to the range of spatial wavevectors available.…

Optics · Physics 2011-01-11 Michael Mazilu , Joerg Baumgartl , Kishan Dholakia

A lens performs an approximately one-to-one mapping from the object to the image planes. This mapping in the image plane is maintained within a depth of field (or referred to as depth of focus, if the object is at infinity). This…

The triangulation of images has become an active research area in recent years for its compressive representation and ease of image processing and visualization. However, little work has been done on how to faithfully recover image…

Computer Vision and Pattern Recognition · Computer Science 2014-06-30 Ke Liu , Ming Xu , Zeyun Yu

Adaptive optics methods have long been used to perform complex light shaping at the output of a multimode fiber (MMF), with the specific aim of controlling the emitted beam in the near-field. Gaining control of other emission properties,…

Neural Radiance Fields (NeRF) offer the potential to benefit 3D reconstruction tasks, including aerial photogrammetry. However, the scalability and accuracy of the inferred geometry are not well-documented for large-scale aerial…

Computer Vision and Pattern Recognition · Computer Science 2024-06-07 Ningli Xu , Rongjun Qin , Debao Huang , Fabio Remondino