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Anomaly detection is a well-established field in machine learning, identifying observations that deviate from typical patterns. The principles of anomaly detection could enhance our understanding of how biological systems recognize and…

Populations and Evolution · Quantitative Biology 2025-10-30 Steven A. Frank

Bilinear dynamical systems are ubiquitous in many different domains and they can also be used to approximate more general control-affine systems. This motivates the problem of learning bilinear systems from a single trajectory of the…

Machine Learning · Computer Science 2022-08-31 Yahya Sattar , Samet Oymak , Necmiye Ozay

Discovering the underlying dynamics of complex systems from data is an important practical topic. Constrained optimization algorithms are widely utilized and lead to many successes. Yet, such purely data-driven methods may bring about…

Dynamical Systems · Mathematics 2023-05-17 Nan Chen , Yinling Zhang

Cortical neurons emit seemingly erratic trains of action potentials or "spikes," and neural network dynamics emerge from the coordinated spiking activity within neural circuits. These rich dynamics manifest themselves in a variety of…

Neurons and Cognition · Quantitative Biology 2022-04-01 Braden A. W. Brinkman , Han Yan , Arianna Maffei , Il Memming Park , Alfredo Fontanini , Jin Wang , Giancarlo La Camera

Genes are connected in complex networks of interactions where often the product of one gene is a transcription factor that alters the expression of another. Many of these networks are based on a few fundamental motifs leading to switches…

Molecular Networks · Quantitative Biology 2026-03-05 Zitao Yang , Rebecca J. Rousseau , Sara D. Mahdavi , Hernan G. Garcia , Rob Phillips

Spatio-temporal network dynamics is an emergent property of many complex systems which remains poorly understood. We suggest a new approach to its study based on the analysis of dynamical motifs -- small subnetworks with periodic and…

Disordered Systems and Neural Networks · Physics 2007-05-23 Valentin P. Zhigulin

This paper presents an algorithm for approximating certain types of dynamical systems given by a system of ordinary delay differential equations by a Boolean network model. Often Boolean models are much simpler to understand than complex…

Molecular Networks · Quantitative Biology 2011-05-10 Franziska Hinkelmann , Reinhard Laubenbacher

Learning underlies nearly all human behavior and is central to education and education reform. Although recent advances in neuroscience have revealed the fundamental structure of learning processes, these insights have yet to be integrated…

Information Theory · Computer Science 2025-10-20 Scott E. Allen , A. David Redish , René F. Kizilcec

Neural dynamical systems with stable attractor structures, such as point attractors and continuous attractors, are hypothesized to underlie meaningful temporal behavior that requires working memory. However, working memory may not support…

Neurons and Cognition · Quantitative Biology 2023-08-25 Il Memming Park , Ábel Ságodi , Piotr Aleksander Sokół

Understanding computational capabilities of simple biological circuits, such as the regulatory circuits of single-cell organisms, remains an active area of research. Recent theoretical work has shown that a simple regulatory architecture…

Biological Physics · Physics 2022-11-24 Fang Yu , Mikhail Tikhonov

Traditional activity recognition systems work on the basis of training, taking a fixed set of sensors into account. In this article, we focus on the question how pattern recognition can leverage new information sources without any, or with…

Computer Vision and Pattern Recognition · Computer Science 2017-01-31 David Bannach , Martin Jänicke , Vitor F. Rey , Sven Tomforde , Bernhard Sick , Paul Lukowicz

Recently, it was shown that the amoeba-like cell {\it Physarum polycephalum} when exposed to a pattern of periodic environmental changes learns and adapts its behavior in anticipation of the next stimulus to come. Here we show that such…

Cell Behavior · Quantitative Biology 2009-11-21 Yuriy V. Pershin , Steven La Fontaine , Massimiliano Di Ventra

Learning interpretable representations of neural dynamics at a population level is a crucial first step to understanding how observed neural activity relates to perception and behavior. Models of neural dynamics often focus on either…

Machine Learning · Statistics 2025-01-13 Noga Mudrik , Yenho Chen , Eva Yezerets , Christopher J. Rozell , Adam S. Charles

A hallmark of human intelligence is the ability to adapt to new situations, by applying learned rules to new content (systematicity) and thereby enabling an open-ended number of inferences and actions (generativity). Here, we propose that…

Neurons and Cognition · Quantitative Biology 2021-08-10 Randall C. O'Reilly , Charan Ranganath , Jacob L. Russin

We introduce the delta-homology model of memory, a unified framework in which recall, learning, and prediction emerge from cycle closure, the completion of topologically constrained trajectories within the brain's latent manifold. A…

Machine Learning · Computer Science 2025-10-21 Xin Li

What features characterise complex system dynamics? Power laws and scale invariance of fluctuations are often taken as the hallmarks of complexity, drawing on analogies with equilibrium critical phenomena[1-3]. Here we argue that slow,…

Statistical Mechanics · Physics 2007-05-23 Paul Anderson , Henrik Jeldtoft Jensen , L. P. Oliveira , Paolo Sibani

Networks of coupled dynamical units give rise to collective dynamics such as the synchronization of oscillators or neurons in the brain. The ability of the network to adapt coupling strengths between units in accordance with their activity…

Adaptation and Self-Organizing Systems · Physics 2023-05-17 Benjamin Jüttner , Erik Andreas Martens

We apply the renormalization group theory to the dynamical systems with the simplest example of basic biological motifs. This includes the interpretation of complex networks as the perturbation to simple network. This is the first step to…

Other Quantitative Biology · Quantitative Biology 2016-09-13 Masamichi Sato

For a general class of translationally invariant systems with a specific category of nonlinearity in the output, this paper presents necessary and sufficient conditions for global observability. Critically, this class of systems cannot be…

Dynamical Systems · Mathematics 2022-10-11 Eduardo D. Sontag , Debojyoti Biswas , Noah J. Cowan

Undulatory locomotion is a means of self-propulsion that relies on the generation and propagation of waves along a body. As a mode of locomotion it is primitive and relatively simple, yet can be remarkably robust. No wonder then, that it is…

Biological Physics · Physics 2009-08-20 Netta Cohen , Jordan H. Boyle