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Infectious disease remains, despite centuries of work to control and mitigate its effects, a major problem facing humanity. This paper reviews the mathematical modelling of infectious disease epidemics on networks, starting from the…

Popular Physics · Physics 2015-06-03 Thomas House

The immune response to a pathogen has two basic features. The first is the expansion of a few pathogen-specific cells to form a population large enough to control the pathogen. The second is the process of differentiation of cells from an…

Populations and Evolution · Quantitative Biology 2014-02-04 Sean P Stromberg , Rustom Antia , Ilya Nemenman

The spatial propagation of many livestock infectious diseases critically depends on the animal movements among premises; so the knowledge of movement data may help us to detect, manage and control an outbreak. The identification of robust…

Populations and Evolution · Quantitative Biology 2012-10-03 Paolo Bajardi , Alain Barrat , Lara Savini , Vittoria Colizza

In dynamic models of infectious disease transmission, typically various mixing patterns are imposed on the so-called Who-Acquires-Infection-From-Whom matrix (WAIFW). These imposed mixing patterns are based on prior knowledge of age-related…

Random walk is one of the basic mechanisms found in many network applications. We study the epidemic spreading dynamics driven by biased random walks on complex networks. In our epidemic model, each time infected nodes constantly spread…

Physics and Society · Physics 2015-06-22 Cunlai Pu , Siyuan Li , Jian Yang

Increasing rates of global trade and travel, as well as changing climatic patterns, have led to more frequent outbreaks of plant disease epidemics worldwide. Mathematical modelling is a key tool in predicting where and how these new threats…

Populations and Evolution · Quantitative Biology 2019-11-28 Frédéric Fabre , Jérôme Coville , Nik J. Cunniffe

Interactions among multiple infectious agents are increasingly recognized as a fundamental issue in the understanding of key questions in public health, regarding pathogen emergence, maintenance, and evolution. The full description of…

Populations and Evolution · Quantitative Biology 2013-08-21 Chiara Poletto , Sandro Meloni , Vittoria Colizza , Yamir Moreno , Alessandro Vespignani

Reconstructing transmission networks is essential for identifying key factors like superspreaders and high-risk locations, which are critical for developing effective pandemic prevention strategies. In this study, we developed a Bayesian…

Quantitative Methods · Quantitative Biology 2024-09-10 Jianing Xu , Huimin Hu , Gregory Ellison , Lili Yu , Christopher Whalen , Liang Liu

This paper develops and analyzes optimization models for rapid detection of viruses in large contact networks. In the model, a virus spreads in a stochastic manner over an undirected connected graph, under various assumptions on the spread…

Optimization and Control · Mathematics 2021-06-16 Sudesh K. Agrawal , John J. Hasenbein

Biofilm infections on medical implants are difficult to eradicate because insufficient nutrient availability promotes antibiotic-tolerant persister cells that survive treatment and reseed growth. Existing mathematical models usually omit…

Populations and Evolution · Quantitative Biology 2025-09-23 Parna Mandal , Nigel J. Mottram , Sean McGinty

We introduce and analyze coupled, multi-strain epidemic models designed to simulate the emergence and dissemination of mutant (e.g. drug-resistant) pathogen strains. In particular, we investigate the mathematical and biological properties…

Populations and Evolution · Quantitative Biology 2017-05-10 Michael T. Meehan , Daniel G. Cocks , James M. Trauer , Emma S. McBryde

Disease progression models infer group-level temporal trajectories of change in patients' features as a chronic degenerative condition plays out. They provide unique insight into disease biology and staging systems with individual-level…

Machine Learning · Computer Science 2025-06-25 Peter A. Wijeratne , Daniel C. Alexander

During an infectious disease outbreak, providing accurate answers to policy questions about transmission requires a detailed model of the natural history of infectiousness. Unfortunately, direct measures of infectiousness are generally…

Mosquito vector competence is usually represented as a process in which once virus is detected in saliva, mosquitoes are assumed to remain infectious for life, implying an irreversible transition to the transmitting state. However, some…

Populations and Evolution · Quantitative Biology 2026-04-30 Léa Loisel , Tristan Monrocq , Vincent Raquin , Pauline Ezanno , Gaël Beaunée

Several systems can be modeled as sets of interdependent networks where each network contains distinct nodes. Diffusion processes like the spreading of a disease or the propagation of information constitute fundamental phenomena occurring…

Social and Information Networks · Computer Science 2015-06-23 Mostafa Salehi , Payam Siyari , Matteo Magnani , Danilo Montesi

This paper introduces an innovative model for infectious diseases in predator-prey populations. We not only prove the existence of global non-negative solutions but also establish essential criteria for the system's decline and…

Populations and Evolution · Quantitative Biology 2023-06-16 Yujie Gao , Malay Banerjee , Ton Viet Ta

Epidemic spreading phenomena are ubiquitous in nature and society. Examples include the spreading of diseases, information, and computer viruses. Epidemics can spread by local spreading, where infected nodes can only infect a limited set of…

Physics and Society · Physics 2024-01-02 Changwang Zhang , Shi Zhou , Joel C. Miller , Ingemar J. Cox , Benjamin M. Chain

We consider a model for an epidemic in a population that occupies geographically distinct locations. The disease is spread within subpopulations by contacts between infective and susceptible individuals, and is spread between subpopulations…

Probability · Mathematics 2016-02-15 R. McVinish , P. K. Pollett , A. Shausan

Epidemics are emergent phenomena depending on the epidemiological characteristics of pathogens and the interaction and movement of people. Public transit systems have provided much important information about the movement of people, but…

Social and Information Networks · Computer Science 2018-09-24 Zhanwei Du , Chao Gao , Yuan Bai , Yongjian Yang , Petter Holme

The aim of this paper is to present an, admittedly somewhat subjective, bird's eye view of the mathematical theory concerning the spread of an infectious disease in a susceptible host population with static structure, culminating in a…

Populations and Evolution · Quantitative Biology 2025-08-06 Odo Diekmann , Hisashi Inaba , Horst R. Thieme
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