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We study random, finite-dimensional, ungraded chain complexes over a finite field and show that for a uniformly distributed differential a complex has the smallest possible homology with the highest probability: either zero or…

Combinatorics · Mathematics 2017-07-05 Viktor L. Ginzburg , Dmitrii V. Pasechnik

Due to its polyionic character the DNA double helix is stable and biologically active only in salty aqueous media where its charge is compensated by solvent counterions. Monovalent metal ions are ubiquitous in DNA environment and they are…

Biological Physics · Physics 2007-05-23 Alexey K. Mazur

We use optical tweezers to perform stretching experiments on DNA molecules when interacting with the drugs daunomycin and ethidium bromide, which intercalate the DNA molecule. These experiments are performed in the low-force regime from…

Biological Physics · Physics 2009-11-13 M. S. Rocha , M. C. Ferreira , O. N. Mesquita

Biology is full of intricate molecular structures whose geometries are inextricably linked to their function. Many of these structures exhibit varying curvature, such as the helical structure of the bacterial flagellum, which is critical…

Most living systems rely on double-stranded DNA (dsDNA) to store their genetic information and perpetuate themselves. This biological information has been considered the main target of evolution. However, here we show that symmetries and…

Biomolecules · Quantitative Biology 2025-05-01 Piero Fariselli , Cristian Taccioli , Luca Pagani , Amos Maritan

We examine the crystallization dynamics of nanoparticles reversibly tethered by DNA hybridization. We show that the crystallization happens readily only in a narrow temperature "slot," and always proceeds via a two-step process, mediated by…

Soft Condensed Matter · Physics 2010-08-13 Wei Dai , Sanat K. Kumar , Francis W. Starr

The precision of biochemical signaling is limited by randomness in the diffusive arrival of molecules at their targets. For proteins binding to the specific sites on the DNA and regulating transcription, the ability of the proteins to…

Molecular Networks · Quantitative Biology 2013-08-01 Gasper Tkacik , William Bialek

We show that the D-brane configurations for the five and four-dimensional black holes give the geometry of two and three-dimensional ones as well. The emergence of these lower dimensional black holes from the D-brane configurations for…

High Energy Physics - Theory · Physics 2008-11-26 S. Hyun

Photonic molecules, i.e. artificial structures composed of coherently coupled optical cavities, are paradigmatic systems for investigating fundamental phenomena across photonics, quantum optics and topological physics. In recent years,…

Optics · Physics 2026-05-06 Tiantong Li , Katia Gallo

Materials in which electrons occupy interstitial sites as anions are called electrides and exhibit unusual dimensionality-dependent electronic behavior. These properties make electrides attractive for catalysis, transparent conductors, and…

Materials Science · Physics 2026-01-01 Lee A. Burton

The low-energy physics of (quasi)degenerate one-dimensional systems is typically understood as the particle-like dynamics of kinks between stable, ordered structures. Such dynamics, we show, becomes highly non-trivial when the ground states…

Soft Condensed Matter · Physics 2014-11-27 Cristiano Nisoli , Alexander V. Balatsky

How long threadlike eukaryotic chromosomes fit tidily in the small volume of the nucleus without significant entanglement is just beginning to be understood, thanks to major advances in experimental techniques. Several polymer models, which…

Soft Condensed Matter · Physics 2024-10-03 D. Thirumalai , Guang Shi , Sucheol Shin , Changbong Hyeon

The chiral nature of DNA plays a crucial role in cellular processes. Here we use magnetic tweezers to explore one of the signatures of this chirality, the coupling between stretch and twist deformations. We show that the extension of a…

Biomolecules · Quantitative Biology 2009-09-29 Timothee Lionnet , Sylvain Joubaud , Richard Lavery , David Bensimon , Vincent Croquette

A six-dimensional reversible normal form system occurs in B{\'e}nard-Rayleigh convection between parallel planes, when we look for domain walls intersecting orthogonally (see Buffoni et al [1]). On the truncated system, we prove…

Mathematical Physics · Physics 2025-12-02 Gérard Iooss

The charge density and pair correlation function of three interacting electrons confined within a two-dimensional disc-like hard wall quantum dot are calculated by full numerical diagonalization of the Hamiltonian. The formation of a…

Strongly Correlated Electrons · Physics 2009-10-31 N. Akman , M. Tomak

DNA inside the cellular environment works under a confined space. An intense research of the transcription and replication of DNA in the confined state is structurally significant to command the self assembly of DNA in a chamber or channel.…

Soft Condensed Matter · Physics 2020-01-14 Arghya Maity , Navin Singh

The complexity of the primary structure of human DNA is explored using methods from nonequilibrium statistical mechanics, dynamical systems theory and information theory. The use of chi-square tests shows that DNA cannot be described as a…

Genomics · Quantitative Biology 2015-06-17 A. Provata , C. Nicolis , G. Nicolis

Topology affects physical and biological properties of DNA and impacts fundamental cellular processes, such as gene expression, genome replication, chromosome structure and segregation. In all organisms DNA topology is carefully modulated…

Biomolecules · Quantitative Biology 2019-03-27 P. Bettotti , V. Visone , L. Lunelli , G. Perugino , M. Ciaramella , A. Valenti

The first level of folding of DNA in eukaryotes is provided by the so called '10 nm chromatin fibre', where DNA wraps around histone proteins (approx. 10 nm in size) to form nucleosomes, which go on to create a zig zagging bead on a string…

Biological Physics · Physics 2016-03-23 S. Tesoro , I. Ali , A. N. Morozov , N. Sulaiman , D. Marenduzzo

I present a Hamiltonian model and a computational method suitable to evaluate structural and thermodynamic properties of helical molecules embedded in crowded environments which may confine the space available to the base pair fluctuations.…

Soft Condensed Matter · Physics 2019-12-24 Marco Zoli