Mesoscopic model for nano-channel confined DNA
Soft Condensed Matter
2019-12-24 v1 Biological Physics
Biomolecules
Abstract
I present a Hamiltonian model and a computational method suitable to evaluate structural and thermodynamic properties of helical molecules embedded in crowded environments which may confine the space available to the base pair fluctuations. It is shown that, for the specific case of a short DNA fragment in a nanochannel, the molecule is markedly over-twisted and stretched by narrowing the width of the channel.
Cite
@article{arxiv.1909.03202,
title = {Mesoscopic model for nano-channel confined DNA},
author = {Marco Zoli},
journal= {arXiv preprint arXiv:1909.03202},
year = {2019}
}
Comments
8th International Conference on Mathematical Modeling in Physical Sciences. August 26-29, 2019 - Bratislava, Slovakia