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Data from experiments and theoretical arguments are the two pillars sustaining the job of modelling physical systems through inference. In order to solve the inference problem, the data should satisfy certain conditions that depend also…

Statistical Mechanics · Physics 2023-03-01 Dario Lucente , Andrea Baldassarri , Andrea Puglisi , Angelo Vulpiani , Massimiliano Viale

Non-stationary systems are found throughout the world, from climate patterns under the influence of variation in carbon dioxide concentration, to brain dynamics driven by ascending neuromodulation. Accordingly, there is a need for methods…

Data Analysis, Statistics and Probability · Physics 2024-07-15 Kieran S. Owens , Ben D. Fulcher

Coarse-graining has become an area of tremendous importance within many different research fields. For molecular simulation, coarse-graining bears the promise of finding simplified models such that long-time simulations of large-scale…

Chemical Physics · Physics 2019-09-04 Feliks Nüske , Lorenzo Boninsegna , Cecilia Clementi

Simulations of condensed matter systems often focus on the dynamics of a few distinguished components but require integrating the dynamics of the full system. A prime example is a molecular dynamics simulation of a (macro)molecule in…

Computational Physics · Physics 2024-03-12 Mauricio J. del Razo , Daan Crommelin , Peter G. Bolhuis

Multi-category data arise in diverse fields including marketing, chemistry, public policy, genomics, political science, and ecology. We consider the problem of estimating ratios of category-specific means in a fully nonparametric setting,…

Methodology · Statistics 2025-10-29 Grant Hopkins , Sarah Teichman , Ellen Graham , Amy D Willis

At the nanoscale, random effects govern not only the dynamics of a physical system but may also affect its observation. This work introduces a novel paradigm for coarse graining that eschews the assignment of a unique coarse-grained…

Statistical Mechanics · Physics 2026-02-05 Jann van der Meer , Keiji Saito

While the equilibrium properties, states, and phase transitions of interacting systems are well described by statistical mechanics, the lack of suitable state parameters has hindered the understanding of non-equilibrium phenomena in diverse…

Soft Condensed Matter · Physics 2019-02-20 Stefano Martiniani , Paul M. Chaikin , Dov Levine

A major current challenge poses the systematic construction of coarse-grained models that are dynamically consistent, and, moreover, might be used for systems driven out of thermal equilibrium. Here we present a novel prescription that…

Statistical Mechanics · Physics 2016-08-05 Fabian Knoch , Thomas Speck

A novel approach to the problem of partial state estimation of nonlinear systems is proposed. The main idea is to translate the state estimation problem into one of estimation of constant, unknown parameters related to the systems initial…

Systems and Control · Computer Science 2016-04-08 Ortega Romeo , Bobtsov Alexey , Pyrkin Anton , Aranovskiy Stanislav

In many far-from-equilibrium biological systems, energy injected by irreversible processes at microscopic scales propagates to larger scales to fulfill important biological functions. But given dissipative dynamics at the microscale, how…

Statistical Mechanics · Physics 2025-06-03 Qiwei Yu , Matthew P. Leighton , Christopher W. Lynn

In the course of computer modeling of the most probable stationary macrostates of non-ergodic closed systems, a forecast was obtained about the existence of limits of applicability of the basic axiomatic postulate of statistical physics,…

Statistical Mechanics · Physics 2024-11-18 Vladimir Savukov

We derive steerability criteria applicable for both finite and infinite dimensional quantum systems using covariance matrices of local observables. We show that these criteria are useful to detect a wide range of entangled states…

Quantum Physics · Physics 2016-01-06 Se-Wan Ji , Jaehak Lee , Jiyong Park , Hyunchul Nha

Observability quantification is a key problem in dynamic network sciences. While it has been thoroughly studied for linear systems, observability quantification for nonlinear networks is less intuitive and more cumbersome. One common…

Systems and Control · Electrical Eng. & Systems 2025-11-03 Mohamad H. Kazma , Ahmad F. Taha

Scientists use mathematical modelling to understand and predict the properties of complex physical systems. In highly parameterised models there often exist relationships between parameters over which model predictions are identical, or…

Data Analysis, Statistics and Probability · Physics 2017-03-24 Dhruva V. Raman , James Anderson , Antonis Papachristodoulou

The volume of data that will be produced by the next generation of astrophysical instruments represents a significant opportunity for making unplanned and unexpected discoveries. Conversely, finding unexpected objects or phenomena within…

Instrumentation and Methods for Astrophysics · Physics 2019-09-11 Gary Segal , David Parkinson , Ray P. Norris , Jesse Swan

Markov state models (MSMs) have been broadly adopted for analyzing molecular dynamics trajectories, but the approximate nature of the models that results from coarse-graining into discrete states is a long-known limitation. We show…

Computational Physics · Physics 2021-05-31 John D. Russo , Jeremy Copperman , David Aristoff , Gideon Simpson , Daniel M. Zuckerman

A new method is proposed to numerically extract the diffusivity of a (typically nonlinear) diffusion equation from underlying stochastic particle systems. The proposed strategy requires the system to be in local equilibrium and have…

Statistical Mechanics · Physics 2018-05-09 Peter Embacher , Nicolas Dirr , Johannes Zimmer , Celia Reina

We recently showed that the dynamics of coarse-grained observables in systems out of thermal equilibrium are governed by the non-stationary generalized Langevin equation [J. Chem. Phys. 147, 214110 (2017), J. Chem. Phys. 150, 174118…

Statistical Mechanics · Physics 2021-05-21 Fabian Glatzel , Tanja Schilling

Fluctuations in small biological systems can be crucial for their function. Large-deviation theory characterizes such rare events from the perspective of stochastic processes. In most cases it is very difficult to directly determine the…

Statistical Mechanics · Physics 2013-12-03 Artur Wachtel

We extend observability metrics based on the empirical observability Gramian from deterministic nonlinear systems to nonlinear stochastic systems in order to capture the impact of process noise on observability. We demonstrate that the…

Systems and Control · Electrical Eng. & Systems 2020-06-16 Nathan Powel , Kristi A. Morgansen