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The recent approach based on Hamiltonian systems and the implicit parametri\-za\-tion theorem, provides a general fixed domain approximation method in shape optimization problems, using optimal control theory. In previous works, we have…

Optimization and Control · Mathematics 2022-05-03 Cornel Marius Murea , Dan Tiba

The outbreak of COVID-19 in 2020 has led to a surge in interest in the mathematical modeling of infectious diseases. Such models are usually defined as compartmental models, in which the population under study is divided into compartments…

Populations and Evolution · Quantitative Biology 2021-02-16 Malú Grave , Alex Viguerie , Gabriel F. Barros , Alessandro Reali , Alvaro L. G. A. Coutinho

Our chances to halt epidemic outbreaks rely on how accurately we represent the population structure underlying the disease spread. When analyzing global epidemics this force us to consider metapopulation models taking into account intra-…

Populations and Evolution · Quantitative Biology 2007-12-10 Alexei Vazquez

In this paper we study a diffusive age structured epidemic model with disease transmission between vector and host populations. The dynamics of the populations are described by reaction-diffusion equations, with infection age structure of…

Analysis of PDEs · Mathematics 2017-06-15 William E. Fitzgibbon , Jeffrey J. Morgan , Glenn F. Webb , Yixiang Wu

In Costa Rica, the first known cases of Zika were reported in 2016. We looked at the 2016-2017 Zika outbreak and explored the transmission dynamics using weekly reported data. A nonlinear differential equation single-outbreak model with…

Populations and Evolution · Quantitative Biology 2019-08-07 Fabio Sanchez , Luis Barboza , Paola Vasquez

The challenges posed by epidemics and pandemics are immense, especially if the causes are novel. This article introduces a versatile open-source simulation framework designed to model intricate dynamics of infectious diseases across diverse…

Multiagent Systems · Computer Science 2023-11-17 Zenin Easa Panthakkalakath , Neeraj , Jimson Mathew

The flux of visitors through popular places undoubtedly influences viral spreading -- from H1N1 and Zika viruses spreading through physical spaces such as airports, to rumors and ideas spreading though online spaces such as chatrooms and…

Populations and Evolution · Quantitative Biology 2017-06-29 Pedro D. Manrique , Chen Xu , Pak Ming Hui , Neil F. Johnson

We show that disease transmission models in a spatially heterogeneous environment can have a large number of coexisting endemic equilibria. A general compartmental model is considered to describe the spread of an infectious disease in a…

Classical Analysis and ODEs · Mathematics 2014-04-01 Diána H. Knipl , Gergely Röst

In this paper, we develop a method to estimate the infection-rate of a disease, over a region, as a field that varies in space and time. To do so, we use time-series of case-counts of symptomatic patients as observed in the areal units that…

Applications · Statistics 2024-06-19 Cosmin Safta , Wyatt Bridgman , Jaideep Ray

Aedes Aegypti is the vector of several deadly diseases, including Zika. Effective and sustainable vector control measures must be deployed to keep A. aegypti numbers under control. The distribution of A. Aegypti is subject to spatial and…

Populations and Evolution · Quantitative Biology 2016-08-05 Chathika Gunaratne , Mustafa Ilhan Akbas , Ivan Garibay , Ozlem Ozmen

Spatial models for spread of an epidemic may be mapped onto bond percolation. We point out that with disorder in the strength of contacts between individuals patchiness in the spread of the epidemic is very likely, and the criterion for…

Statistical Mechanics · Physics 2009-11-10 L. M. Sander , C. P. Warren , I. M. Sokolov

In the last two decades dengue cases increased significantly throughout the world. In several regions dengue re-emerged, particularly in Latin America, where dengue cases not only increased but also occurred more frequently. It is therefore…

Populations and Evolution · Quantitative Biology 2022-04-12 Javier Armando Gutierrez , Karina Laneri , Juan Pablo Aparicio , Gustavo Javier Sibona

The SIR model is one of the most prototypical compartmental models in epidemiology. Generalizing this ordinary differential equation (ODE) framework into a spatially distributed partial differential equation (PDE) model is a considerable…

Quantitative Methods · Quantitative Biology 2024-07-11 Su Yang , Weiqi Chu , Panayotis Kevrekidis

In this paper, an epidemic model with spatial dependence is studied and results regarding its stability and numerical approximation are presented. We consider a generalization of the original Kermack and McKendrick model in which the size…

Numerical Analysis · Mathematics 2022-04-05 Bálint Takács , Yiannis Hadjimichael

We examine how spatial heterogeneity combines with mobility network structure to influence vector-borne disease dynamics. Specifically, we consider a Ross-Macdonald-type disease model on $n$ spatial locations that are coupled by host…

Populations and Evolution · Quantitative Biology 2022-04-22 Omar Saucedo , Joseph H. Tien

This paper investigates the long-time dynamics of a nonlocal epidemic model with free boundaries, where a pathogen with density $u(t,x)$ and the infected humans with density $v(t,x)$ evolve according to a reaction-diffusion system with…

Analysis of PDEs · Mathematics 2026-02-06 Yao Chen , Yihong Du , Wan-Tong Li , Rong Wang

We introduce a stochastic household model for vector-borne diseases, in particular as relevant to prominent vectors belonging to the Aedes genus and hence the Zika, chikungunya, and dengue viruses. In this model, vectors remain local to…

Populations and Evolution · Quantitative Biology 2022-03-01 Andrew Black , Andrew Smith , Alun Lloyd , Joshua Ross

This paper is concerned with the long-time dynamics of an epidemic model whose diffusion and reaction terms involve nonlocal effects described by suitable convolution operators, and the epidemic region is represented by an evolving interval…

Analysis of PDEs · Mathematics 2023-03-08 Yihong Du , Wenjie Ni , Rong Wang

Traditional studies about disease dynamics have focused on global stability issues, due to their epidemiological importance. We study a classical SIR-SI model for arboviruses in two different directions: we begin by describing an…

Populations and Evolution · Quantitative Biology 2014-08-28 Max O. Souza

In this work we propose a novel space-dependent multiscale model for the spread of infectious diseases in a two-dimensional spatial context on realistic geographical scenarios. The model couples a system of kinetic transport equations…

Numerical Analysis · Mathematics 2020-12-21 Walter Boscheri , Giacomo Dimarco , Lorenzo Pareschi