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Magnetic resonance imaging (MRI) is the gold standard for brain imaging. Deep learning (DL) algorithms have been proposed to aid in the diagnosis of diseases such as Alzheimer's disease (AD) from MRI scans. However, DL algorithms can suffer…

Computer Vision and Pattern Recognition · Computer Science 2025-09-12 Akshit Achara , Esther Puyol Anton , Alexander Hammers , Andrew P. King

Classification with positive and unlabeled (PU) data frequently arises in bioinformatics, clinical data, and ecological studies, where collecting negative samples can be prohibitively expensive. While prior works on PU data focus on binary…

Methodology · Statistics 2023-04-20 Lili Zheng , Garvesh Raskutti

Neural ranking models (NRMs) have become one of the most important techniques in information retrieval (IR). Due to the limitation of relevance labels, the training of NRMs heavily relies on negative sampling over unlabeled data. In general…

Information Retrieval · Computer Science 2022-09-13 Yinqiong Cai , Jiafeng Guo , Yixing Fan , Qingyao Ai , Ruqing Zhang , Xueqi Cheng

For the early identification, diagnosis, and treatment of mental health illnesses, the integration of deep learning (DL) and machine learning (ML) has started playing a significant role. By evaluating complex data from imaging, genetics,…

Learning from positive and unlabeled data (PU learning) is actively researched machine learning task. The goal is to train a binary classification model based on a training dataset containing part of positives which are labeled, and…

Machine Learning · Statistics 2023-12-29 Wojciech Rejchel , Paweł Teisseyre , Jan Mielniczuk

Diabetic retinopathy (DR) grading is crucial in determining the adequate treatment and follow up of patients, but the screening process can be tiresome and prone to errors. Deep learning approaches have shown promising performance as…

Image and Video Processing · Electrical Eng. & Systems 2020-06-01 Teresa Araújo , Guilherme Aresta , Luís Mendonça , Susana Penas , Carolina Maia , Ângela Carneiro , Ana Maria Mendonça , Aurélio Campilho

Extending the Standard Model (SM) by a $U(1)_{L_\mu-L_\tau}$ group gives potentially significant new contributions to $g_\mu-2$, allows the construction of realistic neutrino mass matrices, incorporates lepton universality violation, and…

High Energy Physics - Phenomenology · Physics 2022-02-18 Manuel Drees , Meng Shi , Zhongyi Zhang

Pre-trained language models (PLMs) have achieved impressive results on various natural language processing tasks. However, recent research has revealed that these models often rely on superficial features and shortcuts instead of developing…

Computation and Language · Computer Science 2025-02-26 Zihao Li , Ruixiang Tang , Lu Cheng , Shuaiqiang Wang , Dawei Yin , Mengnan Du

Model pruning is a performance optimization technique for large language models like R1 or o3-mini. However, existing pruning methods often lead to significant performance degradation or require extensive retraining and fine-tuning. This…

Computation and Language · Computer Science 2025-05-21 Wei Jiang , Anying Fu , Youling Zhang

Offline Reinforcement Learning (RL) aims to learn a near-optimal policy from a fixed dataset of transitions collected by another policy. This problem has attracted a lot of attention recently, but most existing methods with strong…

Machine Learning · Computer Science 2023-05-23 Germano Gabbianelli , Gergely Neu , Nneka Okolo , Matteo Papini

Diabetes has emerged as a significant global health issue, especially with the increasing number of cases in many countries. This trend Underlines the need for a greater emphasis on early detection and proactive management to avert or…

Machine Learning · Computer Science 2025-06-16 Mowafaq Salem Alzboon , Muhyeeddin Alqaraleh , Mohammad Subhi Al-Batah

Deep Generative Models (DGMs) are versatile tools for learning data representations while adequately incorporating domain knowledge such as the specification of conditional probability distributions. Recently proposed DGMs tackle the…

Machine Learning · Computer Science 2024-01-30 Romain Lopez , Jan-Christian Huetter , Ehsan Hajiramezanali , Jonathan Pritchard , Aviv Regev

Lead optimization in drug discovery requires efficiently navigating vast chemical space through iterative cycles to enhance molecular properties while preserving structural similarity to the original lead compound. Despite recent advances,…

Machine Learning · Computer Science 2025-09-29 Ziqing Wang , Yibo Wen , William Pattie , Xiao Luo , Weimin Wu , Jerry Yao-Chieh Hu , Abhishek Pandey , Han Liu , Kaize Ding

Text retrieval plays a crucial role in incorporating factual knowledge for decision making into language processing pipelines, ranging from chat-based web search to question answering systems. Current state-of-the-art text retrieval models…

Computation and Language · Computer Science 2024-11-26 Ge Gao , Jonathan D. Chang , Claire Cardie , Kianté Brantley , Thorsten Joachim

In this paper, we propose a non-negative representation based discriminative dictionary learning algorithm (NRDL) for multicategory face classification. In contrast to traditional dictionary learning methods, NRDL investigates the use of…

Computer Vision and Pattern Recognition · Computer Science 2019-10-01 Zhe Chen , Xiao-Jun Wu , Josef Kittler

Deep learning's success has been attributed to the training of large, overparameterized models on massive amounts of data. As this trend continues, model training has become prohibitively costly, requiring access to powerful computing…

Machine Learning · Computer Science 2021-11-25 Ravi S Raju , Kyle Daruwalla , Mikko Lipasti

Cell and immunotherapy offer transformative potential for treating diseases like cancer and autoimmune disorders by modulating the immune system. The development of these therapies is resource-intensive, with the majority of drug candidates…

Machine Learning · Computer Science 2024-12-04 Katarzyna Janocha , Annabel Ling , Alice Godson , Yulia Lampi , Simon Bornschein , Nils Y. Hammerla

Learning from positive and unlabeled data is known as positive-unlabeled (PU) learning in literature and has attracted much attention in recent years. One common approach in PU learning is to sample a set of pseudo-negatives from the…

Machine Learning · Computer Science 2023-08-02 Zhangchi Zhu , Lu Wang , Pu Zhao , Chao Du , Wei Zhang , Hang Dong , Bo Qiao , Qingwei Lin , Saravan Rajmohan , Dongmei Zhang

In recent years, the power demonstrated by Machine Learning (ML) has increasingly attracted the interest of the optimization community that is starting to leverage ML for enhancing and automating the design of algorithms. One combinatorial…

Machine Learning · Computer Science 2022-09-19 Andrea Corsini , Simone Calderara , Mauro Dell'Amico

Language model (LM) post-training (or alignment) involves maximizing a reward function that is derived from preference annotations. Direct Preference Optimization (DPO) is a popular offline alignment method that trains a policy directly on…

Machine Learning · Computer Science 2025-03-04 Adam Fisch , Jacob Eisenstein , Vicky Zayats , Alekh Agarwal , Ahmad Beirami , Chirag Nagpal , Pete Shaw , Jonathan Berant