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Clinical abnormality grounding for rare diseases is often hindered by data scarcity, making supervised fine-tuning impractical and single-pass inference highly unstable. We propose Dynamic Decision Learning (DDL), a framework that enables…

Computation and Language · Computer Science 2026-04-29 Jun Li , Mingxuan Liu , Jiazhen Pan , Che Liu , Wenjia Bai , Cosmin I. Bercea , Julia A. Schnabel

The study of biological processes can greatly benefit from tools that automatically predict gene functions or directly cluster genes based on shared functionality. Existing data mining methods predict protein functionality by exploiting…

Machine Learning · Computer Science 2020-11-20 Kaiyu Shen , Razvan Bunescu , Sarah E. Wyatt

In many nations, diabetes is becoming a significant health problem, and early identification and control are crucial. Using machine learning algorithms to predict diabetes has yielded encouraging results. Using the Pima Indians Diabetes…

Machine Learning · Computer Science 2025-06-13 Mowafaq Salem Alzboon , Mohammad Al-Batah , Muhyeeddin Alqaraleh , Ahmad Abuashour , Ahmad Fuad Bader

The vast majority of Dimensionality Reduction (DR) techniques rely on second-order statistics to define their optimization objective. Even though this provides adequate results in most cases, it comes with several shortcomings. The methods…

Computer Vision and Pattern Recognition · Computer Science 2017-08-21 Nikolaos Passalis , Anastasios Tefas

Memory, as the basis of learning, determines the storage, update and forgetting of knowledge and further determines the efficiency of learning. Featured with the mechanism of memory, a radial basis function neural network based learning…

Systems and Control · Electrical Eng. & Systems 2023-11-27 Yiming Fei , Jiangang Li , Yanan Li

We propose an automatic diabetic retinopathy (DR) analysis algorithm based on two-stages deep convolutional neural networks (DCNN). Compared to existing DCNN-based DR detection methods, the proposed algorithm have the following advantages:…

Computer Vision and Pattern Recognition · Computer Science 2017-05-03 Yehui Yang , Tao Li , Wensi Li , Haishan Wu , Wei Fan , Wensheng Zhang

The Predictive Normalized Maximum Likelihood (pNML) scheme has been recently suggested for universal learning in the individual setting, where both the training and test samples are individual data. The goal of universal learning is to…

Machine Learning · Computer Science 2020-01-09 Koby Bibas , Yaniv Fogel , Meir Feder

In recent years, Reinforcement Learning (RL) has emerged as a powerful tool for solving a wide range of problems, including decision-making and genomics. The exponential growth of raw genomic data over the past two decades has exceeded the…

Motivated by the emerging needs of personalized preventative intervention in many healthcare applications, we consider a multi-stage, dynamic decision-making problem in the online setting with unknown model parameters. To deal with the…

Machine Learning · Computer Science 2022-11-17 Xinyun Chen , Pengyi Shi , Shanwen Pu

Optimizing the fuel cycle cost through the optimization of nuclear reactor core loading patterns involves multiple objectives and constraints, leading to a vast number of candidate solutions that cannot be explicitly solved. To advance the…

Neural and Evolutionary Computing · Computer Science 2024-07-16 Paul Seurin , Koroush Shirvan

Medical treatments often involve a sequence of decisions, each informed by previous outcomes. This process closely aligns with reinforcement learning (RL), a framework for optimizing sequential decisions to maximize cumulative rewards under…

Machine Learning · Computer Science 2024-10-15 Ali Shirali , Alexander Schubert , Ahmed Alaa

Iterative pruning is one of the most effective compression methods for pre-trained language models. We discovered that finding the optimal pruning decision is an equality-constrained 0-1 Integer Linear Programming problem. The solution to…

Computation and Language · Computer Science 2023-05-23 Siyu Ren , Kenny Q. Zhu

Machine learning (ML) has emerged as a powerful tool for tackling complex regression and classification tasks, yet its success often hinges on the quality of training data. This study introduces an ML paradigm inspired by domain knowledge…

Machine Learning · Computer Science 2025-01-10 Mohsen Rashki

Matching job descriptions (JDs) with suitable talent requires models capable of understanding not only textual similarities between JDs and candidate resumes but also contextual factors such as geographical location and academic seniority.…

Computation and Language · Computer Science 2025-03-17 Yafei Zhang , Murray Wang , Yu Wang , Xiaohui Wang

Multiple instance learning (MIL) was a weakly supervised learning approach that sought to assign binary class labels to collections of instances known as bags. However, due to their weak supervision nature, the MIL methods were susceptible…

Computer Vision and Pattern Recognition · Computer Science 2024-05-27 Wenhui Zhu , Peijie Qiu , Xiwen Chen , Oana M. Dumitrascu , Yalin Wang

In this paper, we propose two distinct solutions to the problem of Diabetic Retinopathy (DR) classification. In the first approach, we introduce a shallow neural network architecture. This model performs well on classification of the most…

Computer Vision and Pattern Recognition · Computer Science 2020-07-21 Hangwei Zhuang , Nabil Ettehadi

This paper presents a novel method which simultaneously learns the number of filters and network features repeatedly over multiple epochs. We propose a novel pruning loss to explicitly enforces the optimizer to focus on promising candidate…

Computer Vision and Pattern Recognition · Computer Science 2019-06-12 Tinghuai Wang , Lixin Fan , Huiling Wang

In recent years, the focus is on improving the diagnosis of diabetic retinopathy (DR) using machine learning and deep learning technologies. Researchers have explored various approaches, including the use of high-definition medical imaging,…

Computer Vision and Pattern Recognition · Computer Science 2024-07-26 Saideep Kilaru , Kothamasu Jayachandra , Tanishka Yagneshwar , Suchi Kumari

Public policies and medical interventions often involve dynamic treatment assignments, in which individuals receive a sequence of interventions over multiple stages. We study the statistical learning of optimal dynamic treatment regimes…

Methodology · Statistics 2025-05-21 Shosei Sakaguchi

Alignment of large language models (LLMs) with human preferences typically relies on supervised reward models or external judges that demand abundant annotations. However, in fields that rely on professional knowledge, such as medicine and…

Artificial Intelligence · Computer Science 2025-11-18 Yiyang Zhao , Huiyu Bai , Xuejiao Zhao