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Describing dynamic medical systems using machine learning is a challenging topic with a wide range of applications. In this work, the possibility of modeling the blood glucose level of diabetic patients purely on the basis of measured data…

Machine Learning · Computer Science 2023-03-10 David Jödicke , Daniel Parra , Gabriel Kronberger , Stephan Winkler

AI procedures joined with wearable gadgets can convey exact transient blood glucose level forecast models. Also, such models can learn customized glucose-insulin elements dependent on the sensor information gathered by observing a few parts…

Machine Learning · Computer Science 2021-01-22 Ignacio Rodriguez

The insulin sensitivity (IS) of the human body changes with a circadian rhythm. This adds to the time-varying feature of the glucose metabolism process and places challenges on the blood glucose (BG) control of patients with Type 1 Diabetes…

Systems and Control · Computer Science 2021-01-29 Lukas Ortmann , Dawei Shi , Eyal Dassau , Francis J. Doyle , Steffen Leonhardt , Berno J. E. Misgeld

Chiral molecule sensing is currently performed using chromatography, electrophoresis, enzymatic-assays, mass spectrometry, and chiroptical sensing techniques. Currently polarimetry is the only method having in-vivo sensing capabilities,…

Medical Physics · Physics 2024-01-22 Swathi Padmanabhan , Jaya Prakash

Traditional detection methods of C-reactive protein (CRP) inflammation biomarker, in blood are expensive, time-consuming and labor-intensive. Such existing point-of-care CRP detection devices remain invasive, since they need blood sampling…

Medical Physics · Physics 2024-07-25 Aristea Grammoustianou , Ali Saeidi , Johan Longo , Felix Risch , Adrian M. Ionescu

Parkinson's disease (PD) is a progressive neurodegenerative disorder that lacks reliable early-stage biomarkers for diagnosis, prognosis, and therapeutic monitoring. While cerebrospinal fluid (CSF) biomarkers, such as alpha-synuclein seed…

Methodology · Statistics 2025-07-02 Samhita Pal , Dhrubajyoti Ghosh , Shu Yang

We demonstrate novel instrumentation for spontaneous Raman spectroscopy in biofluids, enabling development of a portable, automated, reliable diagnostics technique requiring minimal operator expertise to quantify disease markers. Label-free…

Biological Physics · Physics 2021-05-27 Emily E. Storey , Duxuan Wu , Amr S. Helmy

Recent advances in SSL enabled novel medical AI models, known as foundation models, offer great potential for better characterizing health from diverse biomedical data. CGM provides rich, temporal data on glycemic patterns, but its full…

Metabolic disorders present a pressing global health challenge, with China carrying the world's largest burden. While continuous glucose monitoring (CGM) has transformed diabetes care, its potential for supporting sub-health populations --…

Human-Computer Interaction · Computer Science 2025-11-04 Dongyijie Primo Pan , Lan Luo , Yike Wang , Pan Hui

Integrated photonic biosensors provide compact, highly sensitive, and label-free platforms for biochemical detection, making them attractive for on-chip and real-time sensing applications. However, their design remains challenging due to…

Optics · Physics 2026-02-24 Yasaman Torabi , Amirali Ekhteraei , Mohammad Khajezadeh

Structured illumination microscopy (SIM) has attained high spatiotemporal delineation of subcellular architecture, yet offers limited insight into chemical composition. We develop Chem-SIM, a structured-illumination fluorescence detected…

The Cellular Potts Model (CPM) is a widely used simulation paradigm for systems of interacting cells that has been used to study scenarios ranging from plant development to morphogenesis, tumour growth and cell migration. Despite their wide…

Tissues and Organs · Quantitative Biology 2023-12-18 Shabaz Sultan , Sapna Devi , Scott N. Mueller , Johannes Textor

In this work, the blood NIR absorbances are recorded using the FT-IR method. It is shown that when the absorbance curves are multiplied by the first derivative of the water absorbance spectrum as well as by the first derivative of the…

Medical Physics · Physics 2025-07-22 Hadi Barati , Arian Mousavi Madani , Soheil Moradi , Mehdi Fardmanesh

Conventional spectrometer and polarimeter systems rely on bulky optics, fundamentally limiting compact integration and hindering multi-dimensional optical sensing capabilities. Here, we propose a spectropolarimeter enabled by…

Optics · Physics 2026-04-13 Jumin Qiu , Tingting Liu , Chenxuan Xiang , Tianbao Yu , Qiegen Liu , Shuyuan Xiao

Inertial Measurement Unit (IMU) sensors are present in everyday devices such as smartphones and fitness watches. As a result, the array of health-related research and applications that tap onto this data has been growing, but little…

Machine Learning · Computer Science 2021-08-23 Davi Pedrosa de Aguiar , Fabricio Murai

The aim of this paper is to introduce current advances in technology that could enable the development of fully drinkable and autonomous bio-electronic CMOS sensors in the form of dust particles, capable of identifying the source of a…

Applied Physics · Physics 2018-05-17 Sandro Carrara , Pantelis Georgiou

Wearable exoskeletons hold transformative promise for restoring mobility across diverse users with muscular weakness or other impairments. However, their translation beyond laboratory environments remains limited by sensing systems that…

Systems and Control · Electrical Eng. & Systems 2025-10-20 Chenyu Tang , Yu Zhu , Josée Mallah , Wentian Yi , Luyao Jin , Zibo Zhang , Shengbo Wang , Muzi Xu , Ming Shen , Calvin Kalun Or , Shuo Gao , Shaoping Bai , Luigi G. Occhipinti

Clinical laboratory tests provide essential biochemical measurements for diagnosis and treatment, but are limited by intermittent and invasive sampling. In contrast, photoplethysmogram (PPG) is a non-invasive, continuously recorded signal…

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