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We demonstrate an electro-optic wide-field method to enable fluorescence lifetime microscopy (FLIM) with high throughput and single-molecule sensitivity. Resonantly driven Pockels cells are used to efficiently gate images at 39 MHz,…

Optics · Physics 2021-09-23 Adam J. Bowman , Mark A. Kasevich

We present a novel Relativistic Semi-Implicit Method (RelSIM) for particle-in-cell (PIC) simulations of astrophysical plasmas, implemented in a code framework ready for production runs. While explicit PIC methods have gained widespread…

High Energy Astrophysical Phenomena · Physics 2023-08-29 Fabio Bacchini

Photoplethysmogram (PPG) signal-based blood pressure (BP) estimation is a promising candidate for modern BP measurements, as PPG signals can be easily obtained from wearable devices in a non-invasive manner, allowing quick BP measurement.…

Signal Processing · Electrical Eng. & Systems 2021-03-01 Hyeongju Kim , Woo Hyun Kang , Hyeonseung Lee , Nam Soo Kim

Photoplethysmography (PPG) is a widely used non-invasive physiological sensing technique, suitable for various clinical applications. Such clinical applications are increasingly supported by machine learning methods, raising the question of…

People with type 1 diabetes (T1D) lack the ability to produce the insulin their bodies need. As a result, they must continually make decisions about how much insulin to self-administer to adequately control their blood glucose levels.…

Machine Learning · Computer Science 2020-09-22 Ian Fox , Joyce Lee , Rodica Pop-Busui , Jenna Wiens

Recently it has been shown that precise dose control and an increase in the overall acquisition speed of atomic resolution scanning transmission electron microscope (STEM) images can be achieved by acquiring only a small fraction of the…

Eating monitoring has remained an open challenge in medical research for years due to the lack of non-invasive sensors for continuous monitoring and the reliable methods for automatic behavior detection. In this paper, we present a pilot…

Machine Learning · Computer Science 2025-02-21 Xu-Lu Zhang , Zhen-Qun Yang , Dong-Mei Jiang , Ga Liao , Qing Li , Ramesh Jain , Xiao-Yong Wei

Time-resolved techniques have been widely used in time-gated and luminescence lifetime imaging. However, traditional time-resolved systems require expensive lab equipment such as high-speed excitation sources and detectors or complicated…

Instrumentation and Detectors · Physics 2023-10-09 Yan Wang , Sina Sadeghi , Rajesh Paul , Zach Hetzler , Evgeny Danilov , Frances S. Ligler , Qingshan Wei

Continuous monitoring of vital signs in Pediatric Intensive Care Units (PICUs) is essential for early detection of clinical deterioration and effective clinical decision-making. However, contact-based sensors such as pulse oximeters may…

Computer Vision and Pattern Recognition · Computer Science 2026-02-19 Mohamed Khalil Ben Salah , Philippe Jouvet , Rita Noumeir

Model interpretability is crucial for establishing AI safety and clinician trust in medical applications for example, in survival modelling with competing risks. Recent deep learning models have attained very good predictive performance but…

Machine Learning · Computer Science 2026-01-26 Dhanesh Ramachandram , Anne Loefler , Surain Roberts , Amol Verma , Maia Norman , Fahad Razak , Conrad Pow , Charles de Mestral

Motion capture using sparse inertial sensors has shown great promise due to its portability and lack of occlusion issues compared to camera-based tracking. Existing approaches typically assume that IMU sensors are tightly attached to the…

Graphics · Computer Science 2025-08-14 Andela Ilic , Jiaxi Jiang , Paul Streli , Xintong Liu , Christian Holz

Computer-generated hologram (CGH) allows for the on-demand scaling and projection of artificially designed target patterns, while incorporating benefits such as a lensless setup and high-frame-rate operation. In this work, we actively…

Optics · Physics 2026-03-09 Liming Li , Zhenguo Zhao , Gongxiang Wei , Wenfei Zhang , Huiqiang Liu

Body Mass Index (BMI), age, height and weight are important indicators of human health conditions, which can provide useful information for plenty of practical purposes, such as health care, monitoring and re-identification. Most existing…

Computer Vision and Pattern Recognition · Computer Science 2022-12-27 Ziqing Li , Xuexin Yu , Xiaocong Lian , Yifeng Wang , Xiangyang Ji

Modern magnetic resonance imaging (MRI) relies on application-specific multi-channel receive coils to achieve high performance, but these coils are typically costly, rigid, and difficult to generalize across anatomies. Recent wireless,…

Medical Physics · Physics 2026-05-26 Yuhan Liu , Xia Zhu , Ke Wu , Artem Kaliaev , Christina A. LeBedis , Stephan W. Anderson , Xin Zhang

Chiroptical enantioselective sensing is gaining traction across various applications. However, intrinsic molecular chiroptical responses are weak, and existing amplification approaches add synthesis, manufacturing, or operational complexity…

Considering the profound transformation affecting pathology practice, we aimed to develop a scalable artificial intelligence (AI) system to diagnose colorectal cancer from whole-slide images (WSI). For this, we propose a deep learning (DL)…

The ability to use coherent light for material science and applications is directly linked to our ability to measure short optical pulses. While free-space optical methods are well-established, achieving this on a chip would offer the…

Simulation of post-prandial pharmacokinetics, such as muscle protein synthesis (MPS) through mTORC1 and insulin-induced glucose uptake, is often challenging due to the computational intensity of the multi-compartmental approach. In this…

Other Quantitative Biology · Quantitative Biology 2026-05-28 Alberto Calderone

In the context of time-series forecasting, we propose a LSTM-based recurrent neural network architecture and loss function that enhance the stability of the predictions. In particular, the loss function penalizes the model, not only on the…

Signal Processing · Electrical Eng. & Systems 2020-09-09 Maxime De Bois , Mounîm A. El Yacoubi , Mehdi Ammi

The integration of compressive sensing with real-time embedded systems opens new possibilities for efficient, low-power biomedical signal acquisition. This paper presents a custom hardware platform based on the RP2350 micro-controller,…

Systems and Control · Electrical Eng. & Systems 2025-07-11 Rens Baeyens , Dennis Laurijssen , Jan Steckel , Walter Daems
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