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Deep learning methods are widely used for medical applications to assist medical doctors in their daily routines. While performances reach expert's level, interpretability (highlight how and what a trained model learned and why it makes a…

Being able to explain the prediction to clinical end-users is a necessity to leverage the power of AI models for clinical decision support. For medical images, saliency maps are the most common form of explanation. The maps highlight…

Medical brain image analysis is a necessary step in Computer Assisted /Aided Diagnosis (CAD) systems. Advancements in both hardware and software in the past few years have led to improved segmentation and classification of various diseases.…

Segmentation of both large and small white matter hyperintensities/lesions in brain MR images is a challenging task which has drawn much attention in recent years. We propose a multi-scale aggregation model framework to deal with…

Weakly supervised nuclei segmentation is a critical problem for pathological image analysis and greatly benefits the community due to the significant reduction of labeling cost. Adopting point annotations, previous methods mostly rely on…

Deep learning techniques have shown great potential in medical image processing, particularly through accurate and reliable image segmentation on magnetic resonance imaging (MRI) scans or computed tomography (CT) scans, which allow the…

In pre-clinical pathology, there is a paradox between the abundance of raw data (whole slide images from many organs of many individual animals) and the lack of pixel-level slide annotations done by pathologists. Due to time constraints and…

In this paper, we address the challenge of few-shot classification in histopathology whole slide images (WSIs) by utilizing foundational vision-language models (VLMs) and slide-level prompt learning. Given the gigapixel scale of WSIs,…

In this work, we present a comparison of a shallow and a deep learning architecture for the automated segmentation of white matter lesions in MR images of multiple sclerosis patients. In particular, we train and test both methods on early…

Multiple Instance Learning (MIL) methods have become increasingly popular for classifying giga-pixel sized Whole-Slide Images (WSIs) in digital pathology. Most MIL methods operate at a single WSI magnification, by processing all the tissue…

Explainable artificial intelligence (AI) techniques are increasingly being explored to provide insights into why AI and machine learning (ML) models provide a certain outcome in various applications. However, there has been limited…

Although machine learning (ML) models of AI achieve high performances in medicine, they are not free of errors. Empowering clinicians to identify incorrect model recommendations is crucial for engendering trust in medical AI. Explainable AI…

Ultra-high field 7-tesla (7T) MRI improves visualization of multiple sclerosis (MS) white matter lesions (WML) but differs sufficiently in contrast and artifacts from 1.5-3T imaging - suggesting that widely used automated segmentation tools…

Objective: Multiple Sclerosis (MS) is an autoimmune, and demyelinating disease that leads to lesions in the central nervous system. This disease can be tracked and diagnosed using Magnetic Resonance Imaging (MRI). Up to now a multitude of…

Multiple sclerosis is an inflammatory autoimmune demyelinating disease that is characterized by lesions in the central nervous system. Typically, magnetic resonance imaging (MRI) is used for tracking disease progression. Automatic image…

Robustness has become one of the most critical problems in machine learning (ML). The science of interpreting ML models to understand their behavior and improve their robustness is referred to as explainable artificial intelligence (XAI).…

Magnetic resonance imaging is a fundamental tool to reach a diagnosis of multiple sclerosis and monitoring its progression. Although several attempts have been made to segment multiple sclerosis lesions using artificial intelligence, fully…

Structural magnetic resonance imaging (MRI) can be used to detect lesions in the brains of multiple sclerosis (MS) patients. The formation of these lesions is a complex process involving inflammation, tissue damage, and tissue repair, all…

There has been a significant surge of interest recently around the concept of explainable artificial intelligence (XAI), where the goal is to produce an interpretation for a decision made by a machine learning algorithm. Of particular…

The current study investigated the use of Explainable Artificial Intelligence (XAI) to improve the accuracy of brain tumor segmentation in MRI images, with the goal of assisting physicians in clinical decision-making. The study focused on…