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Whole Slide Images (WSIs) in digital pathology are used to diagnose cancer subtypes. The difference in procedures to acquire WSIs at various trial sites gives rise to variability in the histopathology images, thus making consistent…

Image and Video Processing · Electrical Eng. & Systems 2022-04-07 Milad Sikaroudi , Shahryar Rahnamayan , H. R. Tizhoosh

Whole-slide images (WSI) in computational pathology have high resolution with gigapixel size, but are generally with sparse regions of interest, which leads to weak diagnostic relevance and data inefficiency for each area in the slide. Most…

Computer Vision and Pattern Recognition · Computer Science 2022-12-14 Boxuan Zhao , Jun Zhang , Deheng Ye , Jian Cao , Xiao Han , Qiang Fu , Wei Yang

Recently, convolutional neural network (CNN) based image super-resolution (SR) methods have achieved significant performance improvement. However, most CNN-based methods mainly focus on feed-forward architecture design and neglect to…

Image and Video Processing · Electrical Eng. & Systems 2021-06-15 Huapeng Wu , Jie Gui , Jun Zhang , James T. Kwok , Zhihui Wei

Semantic segmentation for spherical data is a challenging problem in machine learning since conventional planar approaches require projecting the spherical image to the Euclidean plane. Representing the signal on a fundamentally different…

Computer Vision and Pattern Recognition · Computer Science 2023-07-07 Thomas Walker , Varun Anand , Pavlos Andreadis

In recent years, the availability of digitized Whole Slide Images (WSIs) has enabled the use of deep learning-based computer vision techniques for automated disease diagnosis. However, WSIs present unique computational and algorithmic…

Image and Video Processing · Electrical Eng. & Systems 2021-06-15 Yash Sharma , Aman Shrivastava , Lubaina Ehsan , Christopher A. Moskaluk , Sana Syed , Donald E. Brown

High-resolution wide-angle fisheye images are becoming more and more important for robotics applications such as autonomous driving. However, using ordinary convolutional neural networks or vision transformers on this data is problematic…

Computer Vision and Pattern Recognition · Computer Science 2024-05-09 Oscar Carlsson , Jan E. Gerken , Hampus Linander , Heiner Spieß , Fredrik Ohlsson , Christoffer Petersson , Daniel Persson

With the development of computer-aided diagnosis (CAD) and image scanning technology, Whole-slide Image (WSI) scanners are widely used in the field of pathological diagnosis. Therefore, WSI analysis has become the key to modern digital…

Computer Vision and Pattern Recognition · Computer Science 2021-02-23 Chen Li , Xintong Li , Md Rahaman , Xiaoyan Li , Hongzan Sun , Hong Zhang , Yong Zhang , Xiaoqi Li , Jian Wu , Yudong Yao , Marcin Grzegorzek

Whole slide image (WSI) classification requires repetitive zoom-in and out for pathologists, as only small portions of the slide may be relevant to detecting cancer. Due to the lack of patch-level labels, multiple instance learning (MIL) is…

Computer Vision and Pattern Recognition · Computer Science 2023-11-30 Seongho Keum , Sanghyun Kim , Soojeong Lee , Juho Lee

Analyzing high resolution whole slide images (WSIs) with regard to information across multiple scales poses a significant challenge in digital pathology. Multi-instance learning (MIL) is a common solution for working with high resolution…

How do computers and intelligent agents view the world around them? Feature extraction and representation constitutes one the basic building blocks towards answering this question. Traditionally, this has been done with carefully engineered…

Computer Vision and Pattern Recognition · Computer Science 2020-03-31 Jaime Spencer , Richard Bowden , Simon Hadfield

In this article, we present SWAN: a three-stage, self-supervised wavelet neural network for joint estimation of endmembers and abundances from hyperspectral imagery. The contiguous and overlapping hyperspectral band images are first…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Yassh Ramchandani , Vijayashekhar S S , Jignesh S. Bhatt

Accurate cancer diagnosis remains a critical challenge in digital pathology, largely due to the gigapixel size and complex spatial relationships present in whole slide images. Traditional multiple instance learning (MIL) methods often…

Computer Vision and Pattern Recognition · Computer Science 2024-04-18 Kechun Liu , Wenjun Wu , Joann G. Elmore , Linda G. Shapiro

Deep reinforcement learning (RL) is increasingly deployed in resource-constrained environments, yet the go-to function approximators - multilayer perceptrons (MLPs) - are often parameter-inefficient due to an imperfect inductive bias for…

Machine Learning · Computer Science 2026-02-02 Rajib Mostakim , Reza T. Batley , Sourav Saha

Pathology computing has dramatically improved pathologists' workflow and diagnostic decision-making processes. Although computer-aided diagnostic systems have shown considerable value in whole slide image (WSI) analysis, the problem of…

Computer Vision and Pattern Recognition · Computer Science 2024-11-19 Yonghuang Wu , Xuan Xie , Xinyuan Niu , Chengqian Zhao , Jinhua Yu

We introduce a class of Sparse, Physics-based, and partially Interpretable Neural Networks (SPINN) for solving ordinary and partial differential equations (PDEs). By reinterpreting a traditional meshless representation of solutions of PDEs…

Machine Learning · Computer Science 2021-08-13 Amuthan A. Ramabathiran , Prabhu Ramachandran

Using features extracted from networks pretrained on ImageNet is a common practice in applications of deep learning for digital pathology. However it presents the downside of missing domain specific image information. In digital pathology,…

Computer Vision and Pattern Recognition · Computer Science 2020-01-14 Jacob Gildenblat , Eldad Klaiman

Whole Slide Images (WSIs) play a crucial role in accurate cancer diagnosis and prognosis, as they provide tissue details at the cellular level. However, the rapid growth of computational tasks involving WSIs poses significant challenges.…

Computer Vision and Pattern Recognition · Computer Science 2025-10-30 Doanh C. Bui , Hoai Luan Pham , Vu Trung Duong Le , Tuan Hai Vu , Van Duy Tran , Khang Nguyen , Yasuhiko Nakashima

Graph representation learning seeks to transform complex, high-dimensional graph structures into compact vector spaces that preserve both topology and semantics. Among the various strategies, subgraph-based methods provide an interpretable…

Machine Learning · Computer Science 2025-12-05 Yeamin Kaiser , Muhammed Tasnim Bin Anwar , Bholanath Das

Spatial Transcriptomics (ST) profiles thousands of gene expression values at discrete spots with precise coordinates on tissue sections, preserving spatial context essential for clinical and pathological studies. With rising sequencing…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Yishun Zhu , Jiaxin Qi , Jian Wang , Yuhua Zheng , Jianqiang Huang

Mass spectrometry imaging (MSI) enables label-free visualization of molecular distributions across tissue samples but generates large and complex datasets that require effective peak picking to reduce data size while preserving meaningful…

Computer Vision and Pattern Recognition · Computer Science 2026-03-12 Philipp Weigand , Nikolas Ebert , Shad A. Mohammed , Denis Abu Sammour , Carsten Hopf , Oliver Wasenmüller