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Learning high-quality, self-supervised, visual representations is essential to advance the role of computer vision in biomedical microscopy and clinical medicine. Previous work has focused on self-supervised representation learning (SSL)…

Computer Vision and Pattern Recognition · Computer Science 2023-03-06 Cheng Jiang , Xinhai Hou , Akhil Kondepudi , Asadur Chowdury , Christian W. Freudiger , Daniel A. Orringer , Honglak Lee , Todd C. Hollon

Recent advances in whole slide imaging (WSI) technology have led to the development of a myriad of computer vision and artificial intelligence (AI) based diagnostic, prognostic, and predictive algorithms. Computational Pathology (CPath)…

Developing self-supervised learning (SSL) models that can learn universal and transferable representations of H&E gigapixel whole-slide images (WSIs) is becoming increasingly valuable in computational pathology. These models hold the…

Image and Video Processing · Electrical Eng. & Systems 2024-08-07 Guillaume Jaume , Anurag Vaidya , Andrew Zhang , Andrew H. Song , Richard J. Chen , Sharifa Sahai , Dandan Mo , Emilio Madrigal , Long Phi Le , Faisal Mahmood

Superpixels offer a compact image representation by grouping pixels into coherent regions. Recent methods have reached a plateau in terms of segmentation accuracy by generating noisy superpixel shapes. Moreover, most existing approaches…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Julien Walther , Rémi Giraud , Michaël Clément

Digital pathology provides an excellent opportunity for applying fully convolutional networks (FCNs) to tasks, such as semantic segmentation of whole slide images (WSIs). However, standard FCNs face challenges with respect to…

Computer Vision and Pattern Recognition · Computer Science 2018-07-26 Feng Gu , Nikolay Burlutskiy , Mats Andersson , Lena Kajland Wilen

Understanding the context of complex and cluttered scenes is a challenging problem for semantic segmentation. However, it is difficult to model the context without prior and additional supervision because the scene's factors, such as the…

Computer Vision and Pattern Recognition · Computer Science 2021-04-06 Hiroaki Aizawa , Yukihiro Domae , Kunihito Kato

Image synthesis and image-to-image translation are two important generative learning tasks. Remarkable progress has been made by learning Generative Adversarial Networks (GANs)~\cite{goodfellow2014generative} and cycle-consistent GANs…

Computer Vision and Pattern Recognition · Computer Science 2019-01-21 Wei Sun , Tianfu Wu

Representation learning from Gigapixel Whole Slide Images (WSI) poses a significant challenge in computational pathology due to the complicated nature of tissue structures and the scarcity of labeled data. Multi-instance learning methods…

Image and Video Processing · Electrical Eng. & Systems 2024-05-28 Ali Nasiri-Sarvi , Vincent Quoc-Huy Trinh , Hassan Rivaz , Mahdi S. Hosseini

Modern medical image segmentation methods primarily use discrete representations in the form of rasterized masks to learn features and generate predictions. Although effective, this paradigm is spatially inflexible, scales poorly to…

Computer Vision and Pattern Recognition · Computer Science 2024-03-22 Yejia Zhang , Pengfei Gu , Nishchal Sapkota , Danny Z. Chen

The cancer prognosis on gigapixel Whole-Slide Images (WSIs) has always been a challenging task. To further enhance WSI visual representations, existing methods have explored image pyramids, instead of single-resolution images, in WSIs. In…

Image and Video Processing · Electrical Eng. & Systems 2023-05-15 Pei Liu , Bo Fu , Feng Ye , Rui Yang , Bin Xu , Luping Ji

The Segment Anything Model (SAM) marks a significant advancement in segmentation models, offering robust zero-shot abilities and dynamic prompting. However, existing medical SAMs are not suitable for the multi-scale nature of whole-slide…

Computer Vision and Pattern Recognition · Computer Science 2024-03-19 Hong Liu , Haosen Yang , Paul J. van Diest , Josien P. W. Pluim , Mitko Veta

Recent breakthroughs in object detection and image classification using Convolutional Neural Networks (CNNs) are revolutionizing the state of the art in medical imaging, and microscopy in particular presents abundant opportunities for…

Image and Video Processing · Electrical Eng. & Systems 2020-07-07 Rui Aguiar , Jon Braatz

Recent developments in the field of non-local attention (NLA) have led to a renewed interest in self-similarity-based single image super-resolution (SISR). Researchers usually used the NLA to explore non-local self-similarity (NSS) in SISR…

Computer Vision and Pattern Recognition · Computer Science 2023-05-26 Jian-Nan Su , Min Gan , Guang-Yong Chen , Wenzhong Guo , C. L. Philip Chen

We propose a weakly-supervised framework for the semantic segmentation of circular-scan synthetic-aperture-sonar (CSAS) imagery. The first part of our framework is trained in a supervised manner, on image-level labels, to uncover a set of…

Recently there have been many algorithms proposed for the classification of very high resolution whole slide images (WSIs). These new algorithms are mostly focused on finding novel ways to combine the information from small local patches…

Computer Vision and Pattern Recognition · Computer Science 2023-10-06 Long Nguyen , Aiden Nibali , Joshua Millward , Zhen He

Deep learning enables the modelling of high-resolution histopathology whole-slide images (WSI). Weakly supervised learning of tile-level data is typically applied for tasks where labels only exist on the patient or WSI level (e.g. patient…

Image and Video Processing · Electrical Eng. & Systems 2025-06-09 Abhinav Sharma , Bojing Liu , Mattias Rantalainen

Delineation of cancerous regions in gigapixel whole slide images (WSIs) is a crucial diagnostic procedure in digital pathology. This process is time-consuming because of the large search space in the gigapixel WSIs, causing chances of…

Image and Video Processing · Electrical Eng. & Systems 2020-07-21 Hsien-Tzu Cheng , Chun-Fu Yeh , Po-Chen Kuo , Andy Wei , Keng-Chi Liu , Mong-Chi Ko , Kuan-Hua Chao , Yu-Ching Peng , Tyng-Luh Liu

This paper investigates a fundamental problem of scene understanding: how to parse a scene image into a structured configuration (i.e., a semantic object hierarchy with object interaction relations). We propose a deep architecture…

Computer Vision and Pattern Recognition · Computer Science 2018-01-30 Ruimao Zhang , Liang Lin , Guangrun Wang , Meng Wang , Wangmeng Zuo

Single Image Super-Resolution (SISR) reconstructs high-resolution images from low-resolution inputs, enhancing image details. While Vision Transformer (ViT)-based models improve SISR by capturing long-range dependencies, they suffer from…

Computer Vision and Pattern Recognition · Computer Science 2025-04-10 Junyoung Kim , Youngrok Kim , Siyeol Jung , Donghyun Min

Digital histopathology whole slide images (WSIs) provide gigapixel-scale high-resolution images that are highly useful for disease diagnosis. However, digital histopathology image analysis faces significant challenges due to the limited…

Computer Vision and Pattern Recognition · Computer Science 2026-02-13 Bodong Zhang , Xiwen Li , Hamid Manoochehri , Xiaoya Tang , Deepika Sirohi , Beatrice S. Knudsen , Tolga Tasdizen
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