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We investigate the effect of a Heaviside cut-off on the front propagation dynamics of the so-called Burgers-FisherKolmogoroff-Petrowskii-Piscounov (Burgers-FKPP) advection-reaction-diffusion equation. We prove the existence and uniqueness…

Dynamical Systems · Mathematics 2026-05-25 Nikola Popovic , Mariya Ptashnyk , Zak Sattar

We study the mass-conserved reaction-diffusion system known as the wave-pinning model, which serves as a minimal framework for describing cell polarity. In this model, the interplay between reaction kinetics and slow diffusion forms a sharp…

Dynamical Systems · Mathematics 2026-01-09 Shunsuke Kobayashi , Koya Sakakibara , Taikei Uechi

The present work introduces curvature-based rejection sampling (CURS). This is a method for sampling from a general class of probability densities defined on Riemannian manifolds. It can be used to sample from any probability density which…

Statistics Theory · Mathematics 2025-11-06 Isabella Costa Maia , Marco Congedo , Pedro L. C. Rodrigues , Salem Said

In Cao, Du, Li and Li [8], a nonlocal diffusion model with free boundaries extending the local diffusion model of Du and Lin [12] was introduced and studied. For Fisher-KPP type nonlinearities, its long-time dynamical behaviour is shown to…

Analysis of PDEs · Mathematics 2020-01-28 Yihong Du , Fang Li , Maolin Zhou

Detectors often suffer from performance drop due to domain gap between training and testing data. Recent methods explore diffusion models applied to domain generalization (DG) and adaptation (DA) tasks, but still struggle with large…

Computer Vision and Pattern Recognition · Computer Science 2025-07-01 Boyong He , Yuxiang Ji , Zhuoyue Tan , Liaoni Wu

In the present work, we investigate a model of the invasion of healthy tissue by cancer cells which is described by a system of nonlinear PDEs consisting of a cross-diffusion-reaction equation and two additional nonlinear ordinary…

Numerical Analysis · Mathematics 2023-07-18 Shahin Heydari , Petr Knobloch , Thoma Wick

Invasiveness, one of the hallmarks of tumor progression, represents the tumor's ability to expand into the host tissue by means of several complex biochemical and biomechanical processes. Since certain aspects of the problem present a…

Biological Physics · Physics 2009-11-13 Caterina Guiot , Nicola Pugno , Pier Paolo Delsanto , Thomas S. Deisboeck

The limited ability of Convolutional Neural Networks to generalize to images from previously unseen domains is a major limitation, in particular, for safety-critical clinical tasks such as dermoscopic skin cancer classification. In order to…

Computer Vision and Pattern Recognition · Computer Science 2023-07-04 Katharina Fogelberg , Sireesha Chamarthi , Roman C. Maron , Julia Niebling , Titus J. Brinker

Since its foundations, more than one hundred years ago, the field of structural biology has strived to understand and analyze the properties of molecules and their interactions by studying the structure that they take in 3D space. However,…

Biomolecules · Quantitative Biology 2023-02-27 Gabriele Corso

Modeling of DNA-protein interactions is a complex process involving many important time and length scales. This can be facilitated through the use of coarse-grained models which reduce the number of degrees of freedom and allow efficient…

Geometric data analysis and learning has emerged as a distinct and rapidly developing research area, increasingly recognized for its effectiveness across diverse applications. At the heart of this field lies curvature, a powerful and…

Machine Learning · Computer Science 2025-10-28 Yasharth Yadav , Kelin Xia

Mathematical modelling of tumor growth is one of the most useful and inexpensive approaches to determine and predict the stage, size and progression of tumors in realistic geometries. Moreover, these models has been used to get an insight…

Medical Physics · Physics 2017-08-01 Miguel Martín-Landrove

Advection of entities induced by gradients in attractant concentration fields is observed via diffusiophoresis in colloids and via chemotaxis in microorganisms. Mathematically, both diffusiophoresis and chemotaxis follow similar…

Populations and Evolution · Quantitative Biology 2024-10-07 Benjamin M. Alessio , Ankur Gupta

In this work, we develop new generalization bounds for neural networks trained on data supported on Riemannian manifolds. Existing generalization theories often rely on complexity measures derived from Euclidean geometry, which fail to…

Machine Learning · Computer Science 2025-07-08 Krisanu Sarkar

G-equation is a popular level set model in turbulent combustion, and becomes an advective mean curvature type evolution equation when curvature of a moving flame in a fluid flow is considered: $$ G_t + \left(1-d\,…

Analysis of PDEs · Mathematics 2023-12-20 Hongwei Gao , Ziang Long , Jack Xin , Yifeng Yu

Modern classification algorithms are susceptible to adversarial examples--perturbations to inputs that cause the algorithm to produce undesirable behavior. In this work, we seek to understand and extend adversarial examples across domains…

Machine Learning · Computer Science 2021-12-14 Volodymyr Kuleshov , Evgenii Nikishin , Shantanu Thakoor , Tingfung Lau , Stefano Ermon

For the sake of computational efficiency and for theoretical purposes, in mathematical modelling, the Dirac Delta distributions are often utilized as a replacement for cells or vesicles, since the size of cells or vesicles is much smaller…

Numerical Analysis · Mathematics 2023-11-09 Qiyao Peng , Sander C. Hille

Enhanced diffusion, which describes the accelerated spread of passive scalars due to the interaction between advection and molecular diffusion, has been extensively studied in simplified geometries, such as uniform shear and radial flows.…

Analysis of PDEs · Mathematics 2024-11-04 Rômulo Damasclin Chaves dos Santos , Jorge Henrique de Oliveira Sales

The patch dynamics scheme in equation-free multiscale modelling can efficiently predict the macroscopic behaviours by simulating the microscale problem in a fraction of the space-time domain. The patch dynamics schemes developed so far, are…

Numerical Analysis · Mathematics 2024-05-15 Tanay Kumar Karmakar , Durga Charan Dalal

This paper deals with the existence of traveling fronts guided by the medium for a KPP reaction-diffusion equation coming from a model in population dynamics in which there is spatial spreading as well as genetic mutation of a quantitative…

Analysis of PDEs · Mathematics 2016-03-10 Henri Berestycki , Guillemette Chapuisat