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The extracellular space has an ambiguous role in neuroscience. It is present in every physiologically relevant system and often used as a measurement site in experimental recordings, but it has received subordinate attention compared to the…

Neurons and Cognition · Quantitative Biology 2017-05-02 Jurgis Pods

When a quantum particle moves in a curved space, a geometric potential can arise. In spite of a long history of extensive theoretical studies, to experimentally observe the geometric potential remains to be a challenge. What are the…

Quantum Physics · Physics 2024-08-23 Li-Li Ye , Chen-Di Han , Liang Huang , Ying-Cheng Lai

Calculus and geometry are ubiquitous in the theoretical modelling of scientific phenomena, but have historically been very challenging to apply directly to real data as statistics. Diffusion geometry is a new theory that reformulates…

Differential Geometry · Mathematics 2026-02-09 Iolo Jones , David Lanners

Reaction-diffusion models have been used over decades to study biological systems. In this context, evolution equations for probability distribution functions and the associated stochastic differential equations have nowadays become…

Statistical Mechanics · Physics 2018-10-09 C. Escudero , S. B. Yuste , E. Abad , F. Le Vot

We study reaction-diffusion waves on curved two-dimensional surfaces, and determine the influence of curvature upon the nucleation and propagation of spatially localized waves in an excitable medium modelled by the generic FitzHugh-Nagumo…

Pattern Formation and Solitons · Physics 2014-08-13 Frederike Kneer , Eckehard Schöll , Markus A. Dahlem

A pair of Direct Numerical Simulations is used to investigate curvature and pressure effects. One has a Gaussian test bump and a straight opposite wall, while the other has a straight test wall and a blowing/suction distribution on an…

Fluid Dynamics · Physics 2024-09-04 Philippe Spalart , Kenneth Jansen , Gary Coleman

Shape inference is classically ill-posed, because it involves a map from the (2D) image domain to the (3D) world. Standard approaches regularize this problem by either assuming a prior on lighting and rendering or restricting the domain,…

Computer Vision and Pattern Recognition · Computer Science 2020-08-21 Steven W Zucker

The FKPP equation with a variable growth rate and advection by an incompressible velocity field is considered as a model for plankton dispersed by ocean currents. If the average growth rate is negative then the model has a…

Populations and Evolution · Quantitative Biology 2007-09-04 Daniel A. Birch , Yue-Kin Tsang , William R. Young

We consider the Fisher-KPP equation on a three-dimensional domain surrounded by a thin layer whose diffusion rates are drastically different from that in the bulk. The bulk is isotropic, while the layer is considered to be anisotropic and…

Analysis of PDEs · Mathematics 2023-07-21 Xingri Geng

Domain generalization typically requires data from multiple source domains for model learning. However, such strong assumption may not always hold in practice, especially in medical field where the data sharing is highly concerned and…

Computer Vision and Pattern Recognition · Computer Science 2022-06-30 Quande Liu , Cheng Chen , Qi Dou , Pheng-Ann Heng

Cellular nuclei recognition serves as a fundamental and essential step in the workflow of digital pathology. However, with disparate source organs and staining procedures among histology image clusters, the scanned tiles inherently conform…

Quantitative Methods · Quantitative Biology 2024-07-22 Jianan Fan , Dongnan Liu , Canran Li , Hang Chang , Heng Huang , Filip Braet , Mei Chen , Weidong Cai

We consider a continuum mechanical model of cell invasion through thin membranes. The model consists of a transmission problem for cell volume fraction complemented with continuity of stresses and mass flux across the surfaces of the…

Tissues and Organs · Quantitative Biology 2019-08-06 Mark A. J. Chaplain , Chiara Giverso , Tommaso Lorenzi , Luigi Preziosi

This paper studies the phenomenon of invasion for heterogeneous reaction-diffusion equations in periodic domains with monostable and combustion reaction terms. We give an answer to a question rised by Berestycki, Hamel and Nadirashvili in…

Analysis of PDEs · Mathematics 2020-12-30 Romain Ducasse

We consider a Fisher-KPP equation with density-dependent diffusion and advection, arising from a chemotaxis-growth model. We study its behavior as a small parameter, related to the thickness of a diffuse interface, tends to zero. We…

Analysis of PDEs · Mathematics 2011-04-20 Matthieu Alfaro , Elisabeth Logak

We present a second-order algorithm for approximating solutions to nonlocal diffusive processes in reaction-diffusion equations. The numerical scheme relies on a quadrature method for the spatial discretization and a second-order…

Numerical Analysis · Mathematics 2025-12-24 Loic Cappanera , Gabriela Jaramillo

Incorporating free boundary into time-delayed reaction-diffusion equations yields a compatible condition that guarantees the well-posedness of the initial value problem. With the KPP type nonlinearity we then establish a vanishing-spreading…

Analysis of PDEs · Mathematics 2021-08-03 Ningkui Sun , Jian Fang

We present a simple derivation of the interference pattern in matter-wave interferometry as predicted by a class of master equations, by using the density matrix formalism. We apply the obtained formulae to the most relevant collapse…

Quantum Physics · Physics 2018-02-19 Marko Toroš , Angelo Bassi

The effect of molecule size (excluded volume) and the range of interaction on the surface tension, phase diagram and nucleation properties of a model globular protein is investigated using a combinations of Monte Carlo simulations and…

Statistical Mechanics · Physics 2015-03-13 Patrick Grosfils , James F. Lutsko

Closure modeling - the statistical modeling of missing dynamics in the natural sciences and engineering - is a growing and active area of research. Existing methods for closure modeling are often computationally prohibitive, lack…

Methodology · Statistics 2025-11-27 Eric Crislip , Mohammad Khalil , Teresa Portone , Oksana Chkrebtii , Kyle Neal

Diffusion-driven patterns appear on curved surfaces in many settings, initiated by unstable modes of an underlying Laplacian operator. On a flat surface or perfect sphere, the patterns are degenerate, reflecting translational/rotational…

Soft Condensed Matter · Physics 2025-09-09 John R. Frank , Jemal Guven , Mehran Kardar , Leyna Shackleton
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